scholarly journals High virological failure rates in HIV-1 perinatally infected children in South Africa: A retrospective cohort study

2021 ◽  
Vol 111 (3) ◽  
pp. 255
Author(s):  
Z N Makatini ◽  
J T Blackard ◽  
S Mda ◽  
P Miles ◽  
O Towobola
Keyword(s):  
South Africa ◽  
Cohort Study ◽  
Virological Failure ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Failure Rates ◽  
Perinatally Infected ◽  
Hiv 1

scholarly journals Risk factors for tuberculosis smear non-conversion in Eden district, Western Cape, South Africa, 2007–2013: a retrospective cohort study

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Mandla Mlotshwa ◽  
Natasha Abraham ◽  
Moira Beery ◽  
Seymour Williams ◽  
Sandra Smit ◽  
...  
Keyword(s):  
Risk Factors ◽  
South Africa ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Western Cape

scholarly journals Female Genital Schistosomiasis and HIV-1 incidence in Zambian women: a retrospective cohort study

2021 ◽  
Author(s):  
Amy S Sturt ◽  
Emily L Webb ◽  
Comfort R Phiri ◽  
Maina Mudenda ◽  
Joyce Mapani ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Poisson Regression ◽  
Retrospective Cohort ◽  
Statistical Evidence ◽  
Sexually Active ◽  
Hiv Seroconversion ◽  
Hiv 1 ◽  
Female Genital

Abstract Background Female genital schistosomiasis (FGS) has been associated with prevalent HIV-1. We estimated the incidence of HIV-1 infection in Zambian women with and without FGS. Methods Women (aged 18-31, non-pregnant, sexually active) were invited to participate in this study in January-August 2018 at final follow-up of the HPTN 071 (PopART) Population Cohort. HIV-1 negative participants at enrolment (n=492) were included in this analysis with testing to confirm incident HIV-1 performed in HPTN 071 (PopART). Association of incident HIV-1 infection with FGS (Schistosoma DNA detected by PCR in any genital specimen) was assessed with exact Poisson regression. Results Incident HIV-1 infections were observed in 4.1% (20/492) participants. Women with FGS were twice as likely to seroconvert as women without FGS but with no statistical evidence for a difference (aRR 2.16, 95%CI[0.21–12.30], p=0.33). Exploratory analysis suggested an association with HIV-1 acquisition among women with ≥2 positive genital PCR specimens (RR 6.02, [0.58–34.96]), p=0.13). Conclusions Despite higher HIV seroconversion rates in women with FGS, there was no statistical evidence of association, possibly due to low power. Further longitudinal studies should investigate this association in a setting with higher schistosomiasis endemicity.

scholarly journals Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study

2016 ◽  
Vol 16 (5) ◽  
pp. 565-575 ◽  
Author(s):  
John Gregson ◽  
Michele Tang ◽  
Nicaise Ndembi ◽  
Raph L Hamers ◽  
Soo-Yon Rhee ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
First Line ◽  
Global Epidemiology ◽  
Hiv 1

Increasing body mass index increases complications but not failure rates in microvascular breast reconstruction: A retrospective cohort study

2019 ◽  
Vol 72 (9) ◽  
pp. 1518-1524 ◽  
Author(s):  
Anne C. O'Neill ◽  
Stephanie Sebastiampillai ◽  
Toni Zhong ◽  
Stefan O.P. Hofer
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Breast Reconstruction ◽  
Body Mass ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Failure Rates

scholarly journals Severe adverse events during second-line tuberculosis treatment in the context of high HIV Co-infection in South Africa: a retrospective cohort study

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Kathryn Schnippel ◽  
Rebecca H. Berhanu ◽  
Andrew Black ◽  
Cynthia Firnhaber ◽  
Norah Maitisa ◽  
...  
Keyword(s):  
South Africa ◽  
Cohort Study ◽  
Adverse Events ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Tuberculosis Treatment ◽  
Second Line ◽  
Severe Adverse Events
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