scholarly journals Peer Review #1 of "Factors associated with delayed entry into HIV medical care after HIV diagnosis in a resource-limited setting: Data from a cohort study in India (v0.1)"

2013 ◽  
Keyword(s):  
Cohort Study ◽  
Medical Care ◽  
Peer Review ◽  
Resource Limited Setting ◽  
Hiv Diagnosis ◽  
Delayed Entry ◽  
Factors Associated ◽  
Resource Limited ◽  
Limited Setting

scholarly journals Predictors of Delayed Entry into Medical Care of Children Diagnosed with HIV Infection: Data from an HIV Cohort Study in India

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Gerardo Alvarez-Uria ◽  
Praveen Kumar Naik ◽  
Manoranjan Midde ◽  
Raghavakalyan Pakam
Keyword(s):  
Cohort Study ◽  
Medical Care ◽  
Female Gender ◽  
Hiv Care ◽  
Hiv Diagnosis ◽  
Middle Income ◽  
Delayed Entry ◽  
Middle Income Countries ◽  
Scheduled Castes ◽  
One Year

Data about the attrition before entry into care of children diagnosed with HIV in low- or middle-income countries are scarce. The aim of this study is to describe the attrition before engagement in HIV medical care in 523 children who were diagnosed with HIV from 2007 to 2012 in a cohort study in India. The cumulative incidence of children who entered into care was 87.2% at one year, but most children who did not enter into care within one year were lost to followup. The mortality before entry into care was low (1.3% at one year) and concentrated during the first three months after HIV diagnosis. Factors associated with delayed entry into care were being diagnosed after mother’s HIV diagnosis, belonging to scheduled castes, age <18 months, female gender, and living >90 minutes from the HIV centre. Children whose parents were alive and were living in a rented house were at a higher risk of delayed entry into care than those who were living in an owned house. The results of this study can be used to improve the linkage between HIV testing and HIV care of children diagnosed with HIV in India.

scholarly journals Clinical Characteristics of HIV-Infected Patients Who Survive after the Diagnosis of HIV Infection for More Than 10 Years in a Resource-Limited Setting

2012 ◽  
Vol 11 (6) ◽  
pp. 361-365 ◽  
Author(s):  
Sasisopin Kiertiburanakul ◽  
Pawinee Luengroongroj ◽  
Somnuek Sungkanuparph
Keyword(s):  
Adverse Events ◽  
Hiv Infection ◽  
Resource Limited Setting ◽  
Hiv Care ◽  
Hiv Diagnosis ◽  
Cd4 Counts ◽  
Hiv Rna ◽  
Resource Limited ◽  
Limited Setting

A retrospective cohort study was conducted and 129 patients with a diagnosis of HIV infection for more than 10 years were identified. Half the patients were men and mean (standard deviation, SD) age at HIV diagnosis was 33.2 (9.2) years. One third had a diagnosis of AIDS at cohort entry with median (interquartile range, IQR) CD4 counts of 259 (112-430) cells/mm3. All received antiretroviral therapy with median (IQR) current CD4 counts of 502 (363-607) cells/mm3 and 95% had HIV RNA <50 copies/mL. For adverse events, 28% experienced drug resistance, 27% experienced hospitalization, 59% had dyslipidemia, 35% had creatinine >1.0 mg/dL, and 5% had glucose >126 mg/dL. In conclusion, immunological and virological responses can be achieved among patients with a diagnosis of HIV infection for more than 10 years even in a resource-limited setting. Adverse events are common. Preparation for monitoring and management of these adverse events is a crucial part of successful long-term HIV care.

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