scholarly journals Clinical Characteristics of HIV-Infected Patients Who Survive after the Diagnosis of HIV Infection for More Than 10 Years in a Resource-Limited Setting

2012 ◽  
Vol 11 (6) ◽  
pp. 361-365 ◽  
Author(s):  
Sasisopin Kiertiburanakul ◽  
Pawinee Luengroongroj ◽  
Somnuek Sungkanuparph
Keyword(s):  
Adverse Events ◽  
Hiv Infection ◽  
Resource Limited Setting ◽  
Hiv Care ◽  
Hiv Diagnosis ◽  
Cd4 Counts ◽  
Hiv Rna ◽  
Resource Limited ◽  
Limited Setting

A retrospective cohort study was conducted and 129 patients with a diagnosis of HIV infection for more than 10 years were identified. Half the patients were men and mean (standard deviation, SD) age at HIV diagnosis was 33.2 (9.2) years. One third had a diagnosis of AIDS at cohort entry with median (interquartile range, IQR) CD4 counts of 259 (112-430) cells/mm3. All received antiretroviral therapy with median (IQR) current CD4 counts of 502 (363-607) cells/mm3 and 95% had HIV RNA <50 copies/mL. For adverse events, 28% experienced drug resistance, 27% experienced hospitalization, 59% had dyslipidemia, 35% had creatinine >1.0 mg/dL, and 5% had glucose >126 mg/dL. In conclusion, immunological and virological responses can be achieved among patients with a diagnosis of HIV infection for more than 10 years even in a resource-limited setting. Adverse events are common. Preparation for monitoring and management of these adverse events is a crucial part of successful long-term HIV care.

Late and Low Compliance with Hepatitis B Serology Screening Among HIV-Infected Patients in a Resource-Limited Setting: An Issue to Improve HIV Care

2011 ◽  
Vol 9 (1) ◽  
pp. 54-60 ◽  
Author(s):  
Sasisopin Kiertiburanakul ◽  
Darunee Chotiprasitsakul ◽  
Kalayanee Atamasirikul ◽  
Somnuek Sungkanuparph
Keyword(s):  
Hepatitis B ◽  
Resource Limited Setting ◽  
Hiv Care ◽  
Resource Limited ◽  
Limited Setting

scholarly journals Long-term survival of children following acute peritoneal dialysis in a resource-limited setting

2020 ◽  
Vol 39 (4) ◽  
pp. 469-478
Author(s):  
Michael Abel Alao ◽  
Olayinka Rasheed Ibrahim ◽  
Adanze Onyenonachi Asinobi ◽  
Akinwale Akinsola
Keyword(s):  
Peritoneal Dialysis ◽  
Resource Limited Setting ◽  
Term Survival ◽  
Long Term Survival ◽  
Resource Limited ◽  
Limited Setting

Thyroid Surgery in a Resource-Limited Setting: Feasibility and Analysis of Short- and Long-term Outcomes

2016 ◽  
Vol 156 (3) ◽  
pp. 464-471 ◽  
Author(s):  
Aria Jafari ◽  
David Campbell ◽  
Bruce H. Campbell ◽  
Henry Nono Ngoitsi ◽  
Titus M. Sisenda ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Thyroid Surgery ◽  
Outcomes Research ◽  
Chart Review ◽  
Resource Limited Setting ◽  
Resource Limited ◽  
Sf 36 ◽  
Limited Setting

Objective The present study reviews a series of patients who underwent thyroid surgery in Eldoret, Kenya, to demonstrate the feasibility of conducting long-term (>1 year) outcomes research in a resource-limited setting, impact on the quality of life of the recipient population, and inform future humanitarian collaborations. Study Design Case series with chart review. Setting Tertiary public referral hospital in Eldoret, Kenya. Subjects and Methods Twenty-one patients were enrolled during the study period. A retrospective chart review was performed for all adult patients who underwent thyroid surgery during humanitarian trips (2010-2015). Patients were contacted by mobile telephone. Medical history and physical examination, including laryngoscopy, were performed, and the SF-36 was administered (a quality-of-life questionnaire). Laboratory measurements of thyroid function and neck ultrasound were obtained. Results The mean follow-up was 33.6 ± 20.2 months after surgery: 37.5% of subtotal thyroidectomy patients and 15.4% of lobectomy patients were hypothyroid postoperatively according to serologic studies. There were no cases of goiter recurrence or malignancy. All patients reported postoperative symptomatic improvement and collectively showed positive pre- and postoperative score differences on the SF-36. Conclusion Although limited by a small sample size and the retrospective nature, our study demonstrates the feasibility of long-term surgical and quality-of-life outcomes research in a resource-limited setting. The low complication rates suggest minimal adverse effects of performing surgery in this context. Despite a considerable rate of postoperative hypothyroidism, it is in accordance with prior studies and emphasizes the need for individualized, longitudinal, and multidisciplinary care. Quality-of-life score improvements suggest benefit to the recipient population.

scholarly journals Building laboratory capacity to support HIV care in Nigeria: Harvard/APIN PEPFAR, 2004–2012

2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Donald J. Hamel ◽  
Jean-Louis Sankalé ◽  
Jay O. Samuels ◽  
Abdoulaye D. Sarr ◽  
Beth Chaplin ◽  
...  
Keyword(s):  
Viral Load ◽  
Scale Up ◽  
Hiv Treatment ◽  
Resource Limited Setting ◽  
World Health ◽  
Hiv Care ◽  
Future Health ◽  
Laboratory Capacity ◽  
Resource Limited ◽  
Limited Setting

Introduction: From 2004–2012, the Harvard/AIDS Prevention Initiative in Nigeria, funded through the US President’s Emergency Plan for AIDS Relief programme, scaled up HIV care and treatment services in Nigeria. We describe the methodologies and collaborative processes developed to improve laboratory capacity significantly in a resource-limited setting. These methods were implemented at 35 clinic and laboratory locations.Methods: Systems were established and modified to optimise numerous laboratory processes. These included strategies for clinic selection and management, equipment and reagent procurement, supply chains, laboratory renovations, equipment maintenance, electronic data management, quality development programmes and trainings.Results: Over the eight-year programme, laboratories supported 160 000 patients receiving HIV care in Nigeria, delivering over 2.5 million test results, including regular viral load quantitation. External quality assurance systems were established for CD4+ cell count enumeration, blood chemistries and viral load monitoring. Laboratory equipment platforms were improved and standardised and use of point-of-care analysers was expanded. Laboratory training workshops supported laboratories toward increasing staff skills and improving overall quality. Participation in a World Health Organisation-led African laboratory quality improvement system resulted in significant gains in quality measures at five laboratories.Conclusions: Targeted implementation of laboratory development processes, during simultaneous scale-up of HIV treatment programmes in a resource-limited setting, can elicit meaningful gains in laboratory quality and capacity. Systems to improve the physical laboratory environment, develop laboratory staff, create improvements to reduce costs and increase quality are available for future health and laboratory strengthening programmes. We hope that the strategies employed may inform and encourage the development of other laboratories in resource-limited settings.

scholarly journals Computer-Generated Reminders and Quality of Pediatric HIV Care in a Resource-Limited Setting

PEDIATRICS ◽  
2013 ◽  
Vol 131 (3) ◽  
pp. e789-e796 ◽  
Author(s):  
M. C. Were ◽  
W. M. Nyandiko ◽  
K. T. L. Huang ◽  
J. E. Slaven ◽  
C. Shen ◽  
...  
Keyword(s):  
Resource Limited Setting ◽  
Pediatric Hiv ◽  
Hiv Care ◽  
Resource Limited ◽  
Pediatric Hiv Care ◽  
Limited Setting
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