Aflatoxin Contamination of Red Chili Pepper From Bolivia and Peru, Countries with High Gallbladder Cancer Incidence Rates

Abstract Background There have been reports on regional variation in prevalence of hepatitis B and C, and Clonorchis sinensis (C. sinensis) infection, which indicates potential of spatial variation in liver cancer and gallbladder cancer incidence in Korea. Therefore, we aimed to assess the regional variation of liver and gallbladder cancer incidence and its determinants based on the regional distribution of risk factors, including hepatitis B infection in Korea. Methods This study used an ecological study design and district-level cancer incidence statistics generated by the National Cancer Center. Spatial clusters of liver and gallbladder cancer incidence were detected based on spatial scan statistics using SaTScan™ software. We set the size of maximum spatial scanning window of 25 and 35% of the population at risk for analyses of liver and gallbladder cancer, respectively. Significance level of 0.05 was used to reject the null hypothesis of no cluster. We fitted the Besag-York-Mollie model using integrated nested Laplace approximations to assess factors that influence the regional variation in cancer incidence. Results Spatial clusters with high liver cancer incidence rates were detected in the southwestern and southeastern regions of Korea. High gallbladder cancer incidence rates are clustered in the southeastern region. Regional liver cancer incidence can be accounted for the prevalence of high household income (coefficient, − 0.10; 95% credible interval [CI], − 0.18 to − 0.02), marital status (coefficient, − 0.14; 95% CI, − 0.25 to − 0.03), the incidence of hepatitis B (coefficient, 0.87; 95% CI, 0.29 to 1.44), and liver cancer screening (coefficient, 0.06; 95% CI, 0.00 to 0.12), while gallbladder cancer incidence was related to the prevalence of high household income (coefficient, − 0.03; 95% CI, − 0.05 to 0.00) and living close to a river with a high prevalence of liver fluke infection (coefficient, 0.55; 95% CI, 0.14 to 0.96). Conclusions This study demonstrated geographic variation in liver and gallbladder cancer incidence, which can be explained by determinants such as hepatitis B, income, marital status, and living near a river.

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Time Series Analysis and Prediction on Cancer Incidence Rates

Journal of Medical Discovery ◽

10.24262/jmd.2.3.17030 ◽

2017 ◽

Vol 2 (3) ◽

Author(s):

Liming Xie ◽

Keyword(s):

Time Series ◽

Time Series Analysis ◽

Cancer Incidence ◽

Incidence Rates ◽

Series Analysis ◽

Cancer Incidence Rates

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Faculty Opinions recommendation of Age-related crossover in breast cancer incidence rates between black and white ethnic groups.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1137991.595098 ◽

2008 ◽

Author(s):

Ellen Chang

Keyword(s):

Breast Cancer ◽

Ethnic Groups ◽

Cancer Incidence ◽

Breast Cancer Incidence ◽

Incidence Rates ◽

Black And White ◽

Age Related ◽

White Ethnic ◽

Cancer Incidence Rates

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Prevalence-corrected Prostate Cancer Incidence Rates and Trends

American Journal of Epidemiology ◽

10.1093/aje/155.2.148 ◽

2002 ◽

Vol 155 (2) ◽

pp. 148-152 ◽

Cited By ~ 11

Author(s):

R. M. Merrill

Keyword(s):

Prostate Cancer ◽

Cancer Incidence ◽

Incidence Rates ◽

Prostate Cancer Incidence ◽

Cancer Incidence Rates

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Influence of Diet and Tobacco Smoking on Pancreatic Cancer Incidence in Poland in 1960–2008

Gastroenterology Research and Practice ◽

10.1155/2012/682156 ◽

2012 ◽

Vol 2012 ◽

pp. 1-9 ◽

Cited By ~ 8

Author(s):

Mirosław Jarosz ◽

Włodzimierz Sekuła ◽

Ewa Rychlik

Keyword(s):

Pancreatic Cancer ◽

Cancer Incidence ◽

Tobacco Smoking ◽

Red Meat ◽

Incidence Rates ◽

Dietary Factors ◽

Balance Sheets ◽

Animal Fats ◽

The Relationship ◽

Cancer Incidence Rates

The aim of the study was to investigate the relationship between pancreatic cancer incidence and selected dietary factors, alcohol consumption, and tobacco smoking in Poland in 1960–2008. Data on pancreatic cancer morbidity were derived from the National Cancer Registry and on food consumption from the national food balance sheets. In 1960–1989 correlations were found between pancreatic cancer incidence rates and energy (0.60 for males and 0.57 for females), cholesterol (0.87 and 0.80), fibre (−0.84 and −0.89) and folate (−0.45 and −0.49) intake, the consumption of total fats (0.94 and 0.91), animal fats (0,90 and 0,82), sugar (0.88 and 0.87), cereals (−0.93 and −0.91), and alcohol (0.86 and 0.82). In 1990–2008 morbidity correlated with the consumption of red meat (0.67 and 0.48), poultry (−0.88 and −0.57), and fruit (−0.62 and −0.50). Correlation with tobacco smoking was observed in the whole studied period (0.55 and 0.44). Increased incidence of pancreatic cancer in 1960–1995 was probably related to adverse dietary patterns up to 1989, especially high consumption of fats, sugar, and alcohol. Further positive changes in the diet such as lowering red meat consumption and increasing fruit consumption could influence incidence reduction in recent years. Also changes in tobacco smoking could affect the morbidity.

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