scholarly journals Effect of Sodium-Glucose Cotransporter 2 inhibitors on Weight Reduction in Overweight and Obese Populations without Diabetes: A Systematic Review and a Meta-Analysis

2021 ◽  
Author(s):  
Yun Kyung Cho ◽  
Ye-Jee Kim ◽  
Chang Hee Jung
Keyword(s):  
Systematic Review ◽  
Weight Reduction ◽  
Meta Analysis ◽  
Sodium Glucose Cotransporter

scholarly journals Effects of weight reduction on the breast cancer-related lymphedema: A systematic review and meta-analysis

The Breast ◽  
2020 ◽  
Vol 52 ◽  
pp. 116-121
Author(s):  
Chi-Lin Tsai ◽  
Chih-Yang Hsu ◽  
Wei-Wen Chang ◽  
Yen-Nung Lin
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Weight Reduction ◽  
Meta Analysis ◽  
Breast Cancer Related Lymphedema

scholarly journals Correction to: Sodium–glucose cotransporter 2 inhibitors (SGLT2i) and cardiac arrhythmias: a systematic review and meta‑analysis

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Hang-Long Li ◽  
Gregory Y. H. Lip ◽  
Qi Feng ◽  
Yue Fei ◽  
Yi-Kei Tse ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cardiac Arrhythmias ◽  
Meta Analysis ◽  
Sodium Glucose Cotransporter

scholarly journals Efficacy and safety of sodium-glucose cotransporter 2 inhibitors (SGLT-2is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) in patients with type 2 diabetes: a systematic review and network meta-analysis study protocol

BMJ Open ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. e023206 ◽  
Author(s):  
Humaira Hussein ◽  
Francesco Zaccardi ◽  
Nafeesa N Dhalwani ◽  
Melanie J Davies ◽  
Kamlesh Khunti ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Controlled Trials ◽  
Efficacy And Safety ◽  
Sodium Glucose Cotransporter ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

IntroductionSodium-glucose cotransporter 2 inhibitors (SGLT-2is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) are two classes of glucose-lowering drugs gaining popularity in the treatment of type 2 diabetes mellitus (T2DM). Current guidelines suggest patient-centred approaches when deciding between available hyperglycaemia drugs with no indication to which specific drug should be administered. Despite systematic reviews and meta-analyses being conducted within SGLT-2is and GLP-1RAs, differences across these classes of drugs have not been investigated. Therefore, this systematic review and network meta-analysis (NMA) will aim to compare the efficacy and safety profiles across and within SGLT-2is and GLP-1RAs.MethodsPubMed, the Cochrane Central Register of Controlled Trials and ISI Web of Science will be searched from inception for published randomised controlled trials conducted in patients with T2DM, with at least two arms consisting of SGLT-2is, GLP-1RAs or control/placebo. Title and abstracts will be screened by two independent reviewers with conflicts resolved by a third. Data will be extracted by the primary researcher, a random sample will be checked by an independent reviewer. Risk of bias will be assessed using the Cochrane Risk of Bias Tool and overall quality of evidence will be assessed using the Grading of Recommendations Assessment, Development and Evaluation approach.Study characteristics, participants baseline characteristics, mean change in cardiometabolic outcomes and number of adverse events will be extracted for each study. Primary outcome will be the mean change in glycated haemoglobin (HbA1c) (%, mmol/mol). Initial random-effects pairwise meta-analysis will be conducted for each unique treatment comparison where heterogeneity will be assessed. A Bayesian NMA approach will be adopted where random-effects generalised linear models will be fitted in WinBUGS. Sensitivity analysis will be conducted to assess choices of prior distributions and length of burn-in and sample.Ethics and disseminationEthics approval is not required for this study. Results from this study will be published in a peer-review journal.PROSPERO registration numberCRD42018091306.

scholarly journals Cost Utility of Sodium-Glucose Cotransporter 2 Inhibitors in the Treatment of Metformin Monotherapy Failed Type 2 Diabetes Patients: A Systematic Review and Meta-Analysis

2019 ◽  
Vol 22 (12) ◽  
pp. 1458-1469 ◽  
Author(s):  
Bhavani Shankara Bagepally ◽  
Yogesh Krishnarao Gurav ◽  
Thunyarat Anothaisintawee ◽  
Sitaporn Youngkong ◽  
Usa Chaikledkaew ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Meta Analysis ◽  
Cost Utility ◽  
Sodium Glucose Cotransporter ◽  
Metformin Monotherapy ◽  
Diabetes Patients
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