Changes in the Hydrophobization Efficiency of Paper by Humidification Pretreatment during Gas Grafting Treatment Using Palmitoyl Chloride

2020 ◽  
Vol 52 (6) ◽  
pp. 25-33
Author(s):  
Kyoung-Hwa Choi ◽  
Ji-Seon Choi ◽  
Kwang-Seob Lee ◽  
Eun-Seon Lee ◽  
Jeong-Yong Ryu
Keyword(s):  
Palmitoyl Chloride

scholarly journals A method for S- and O-palmitoylation of peptides: synthesis of pulmonary surfactant protein-C models

1999 ◽  
Vol 343 (3) ◽  
pp. 557-562 ◽  
Author(s):  
Esmail YOUSEFI-SALAKDEH ◽  
Jan JOHANSSON ◽  
Roger STRÖMBERG
Keyword(s):  
Pulmonary Surfactant ◽  
Protein C ◽  
Surfactant Protein ◽  
Cd Spectroscopy ◽  
Reversed Phase ◽  
Prolonged Treatment ◽  
Surfactant Protein C ◽  
Palmitoyl Chloride ◽  
Α Helix ◽  
Pulmonary Surfactant Protein

A method for O- and S-palmitoylation of non-protected peptides has been developed. The peptides are treated with excess of palmitoyl chloride in 100% trifluoroacetic acid for 10 min at room temperature. The acidic conditions prevent acylation of amino groups, which is only significant after prolonged treatment (hours to days). The tripeptides Gly-Cys-Phe and Gly-Ser-Phe were converted into the respective S- and O-palmitoylated compounds, and the hydrophobic pulmonary surfactant protein-C model peptides, LRIPCCPVNLKRLLVVV [SP-C(1-17)] and FGIPSSPVLKRLLILLLLLLLILLLILGALLMGL [SP-C(Leu)] were converted into their respective S,S- and O,O-dipalmitoylated peptides. The reactions were virtually quantitative, and the palmitoylated peptides were isolated in about 75-80% yield after reversed-phase HPLC purification. CD spectroscopy showed that S,S-dipalmitoylation of SP-C(1-17) affects the peptide secondary structure (substantial increase in the α-helix content) in dodecylphosphocholine micelles.

THE PREPARATION OF LECITHIN FROM L-α-GLYCERYLPHOSPHORYLCHOLINE

1957 ◽  
Vol 35 (1) ◽  
pp. 1165-1170 ◽  
Author(s):  
N. H. Tattrie ◽  
C. S. McArthur
Keyword(s):  
Snake Venom ◽  
Hemolytic Activity ◽  
Anhydrous Chloroform ◽  
Palmitoyl Chloride ◽  
By Products

L-α-Lecithin (dipalmitoyl) has been prepared from L-α-glycerylphosphoryl-choline by acylation with palmitoyl chloride in anhydrous chloroform in a yield of about 31%. This reaction also gives rise to two by-products having hemolytic activity. One of these, although not yet completely characterized, is chromatographically comparable with lysolecithin formed from lecithin by the action of snake venom lecithinase. The second by-product possessing hemolytic activity but chromatographically different from common lysolecithin was shown to be a monoacyl derivative of L-α-glycerylphosphorylcholine.

scholarly journals Bio-Polyethylene-Based Composites Reinforced with Alkali and Palmitoyl Chloride-Treated Coffee Silverskin

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3113 ◽  
Author(s):  
Franco Dominici ◽  
Daniel García García ◽  
Vicent Fombuena ◽  
Francesca Luzi ◽  
Debora Puglia ◽  
...  
Keyword(s):  
Elastic Moduli ◽  
Maximum Stress ◽  
Substantial Reduction ◽  
Absorption Capacity ◽  
Oh Groups ◽  
Coffee Silverskin ◽  
Palmitoyl Chloride ◽  
Reinforcing Agent ◽  
The Matrix ◽  
Poor Adhesion

This work investigates the feasibility of using coffee silverskin (CSS) as a reinforcing agent in biobased polyethylene (BioPE) composites, by adding it in bulk and thin film samples. The effect of two different treatments, alkali bleaching (CSS_A) and esterification with palmitoyl chloride (CSS_P), on mechanical, thermal, morphological and water absorption behavior of produced materials at different CSS loading (10, 20 and 30 wt %) was investigated. A reactive graft copolymerization of BioPE with maleic anhydride was considered in the case of alkali treated CSS. It was found that, when introduced in bulk samples, improvement in the elastic modulus and a reduction in strain at maximum stress were observed with the increase in CSS fraction for the untreated and treated CSS composites, while the low aspect ratio of the CSS particles and their poor adhesion with the polymeric matrix were responsible for reduced ductility in films, decreasing crystallinity values and reduction of elastic moduli. When CSS_A and CSS_P are introduced in the matrix, a substantial reduction in the water uptake is also obtained in films, mainly due to presence of maleated PE, that builds up some interactions to eliminate the amounts of OH groups and hydrophobized CSS, due to the weakened absorption capacity of the functionalized CSS.

scholarly journals Preparation of Benzothiazolyl-Decorated Nanoliposomes

Molecules ◽  
2019 ◽  
Vol 24 (8) ◽  
pp. 1540 ◽  
Author(s):  
Spyridon Mourtas ◽  
Panayiota Christodoulou ◽  
Pavlos Klepetsanis ◽  
Dimitrios Gatos ◽  
Kleomenis Barlos ◽  
...  
Keyword(s):  
Plasma Proteins ◽  
Hplc Analysis ◽  
Physical Stability ◽  
Membrane Integrity ◽  
Amyloid Β ◽  
Subsequent Reduction ◽  
High Affinity ◽  
Palmitoyl Chloride ◽  
High Integrity ◽  
First Time

Amyloid β (Aβ) species are considered as potential targets for the development of diagnostics/therapeutics towards Alzheimer’s disease (AD). Nanoliposomes which are decorated with molecules having high affinity for Aβ species may be considered as potential carriers for AD theragnostics. Herein, benzothiazolyl (BTH) decorated nanoliposomes were prepared for the first time, after synthesis of a lipidic BTH derivative (lipid-BTH). The synthetic pathway included acylation of bis(2-aminophenyl) disulfide with palmitic acid or palmitoyl chloride and subsequent reduction of the oxidized dithiol derivative. The liberated thiols were able to cyclize to the corresponding benzothiazolyl derivatives only after acidification of the reaction mixture. Each step of the procedure was monitored by HPLC analysis in order to identify all the important parameters for the formation of the BTH-group. Finally, the optimal methodology was identified, and was applied for the synthesis of the lipid-BTH derivative. BTH-decorated nanoliposomes were then prepared and characterized for physicochemical properties (size distribution, surface charge, physical stability, and membrane integrity during incubation in presence of buffer and plasma proteins). Pegylated BTH-nanoliposomes were demonstrated to have high integrity in the presence of proteins (in comparison to non-peglated ones) justifying their further exploitation as potential theragnostic systems for AD.

Artificial Aging Characteristics of Hydrophobic Hanjis Grafted by Gaseous Palmitoyl Chloride

2019 ◽  
Vol 51 (3) ◽  
pp. 98-107
Author(s):  
Kyoung-Hwa Choi ◽  
Kwang Seob Lee ◽  
Jae-Hoon Lee ◽  
Myoung-Ku Lee ◽  
Jeong-Yong Ryu
Keyword(s):  
Artificial Aging ◽  
Palmitoyl Chloride

Efficiency of Hydrophobization of PVA Coating Layer Gas-Grafted with Palmitoyl Chloride

2018 ◽  
Vol 50 (4) ◽  
pp. 123-134
Author(s):  
Kwang-Seob Lee ◽  
Jae-Hun Lee ◽  
Myoung-Ku Lee ◽  
Jeong-Yong Ryu
Keyword(s):  
Coating Layer ◽  
Palmitoyl Chloride

scholarly journals Synthesis, Stability, and Antidiabetic Activity Evaluation of (−)-Epigallocatechin Gallate (EGCG) Palmitate Derived from Natural Tea Polyphenols

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 393
Author(s):  
Bingbing Liu ◽  
Zhengzhong Kang ◽  
Weidong Yan
Keyword(s):  
Synthesis Method ◽  
Epigallocatechin Gallate ◽  
Antidiabetic Activity ◽  
Molar Ratio ◽  
Synthetic Approach ◽  
Vitro Assay ◽  
Docking Simulations ◽  
Palmitoyl Chloride ◽  
Novel Approach

This work describes a novel approach for the synthesis of (−)-epigallocatechin gallate (EGCG) palmitate by a chemical-synthesis method, where the elevated stability of the EGCG derivative is achieved. Various parameters affecting the acylation process, such as the base, solvent, as well as the molar ratio of palmitoyl chloride, have been studied to optimize the acylation procedure. The optimized reaction condition was set as follows: EGCG/palmitoyl chloride/sodium acetate was under a molar ratio of 1:2:2, with acetone as the solvent, and the reaction temperature was 40 °C. Under the optimized condition, the yield reached 90.6%. The EGCG palmitate (PEGCG) was isolated and identified as 4′-O-palmitoyl EGCG. Moreover, the stability of PEGCG under different conditions was proved significantly superior to EGCG. Finally, PEGCG showed better inhibition towards α-amylase and α-glucosidase, which was 4.5 and 52 times of EGCG, respectively. Molecular docking simulations confirmed the in vitro assay results. This study set a novel and practical synthetic approach for the derivatization of EGCG, and suggest that PEGCG may act as an antidiabetic agent.

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