scholarly journals A quantization assisted U-Net study with ICA and deep features fusion for breast cancer identification using ultrasonic data

2021 ◽  
Vol 7 ◽  
pp. e805
Author(s):  
Talha Meraj ◽  
Wael Alosaimi ◽  
Bader Alouffi ◽  
Hafiz Tayyab Rauf ◽  
Swarn Avinash Kumar ◽  
...  

Breast cancer is one of the leading causes of death in women worldwide—the rapid increase in breast cancer has brought about more accessible diagnosis resources. The ultrasonic breast cancer modality for diagnosis is relatively cost-effective and valuable. Lesion isolation in ultrasonic images is a challenging task due to its robustness and intensity similarity. Accurate detection of breast lesions using ultrasonic breast cancer images can reduce death rates. In this research, a quantization-assisted U-Net approach for segmentation of breast lesions is proposed. It contains two step for segmentation: (1) U-Net and (2) quantization. The quantization assists to U-Net-based segmentation in order to isolate exact lesion areas from sonography images. The Independent Component Analysis (ICA) method then uses the isolated lesions to extract features and are then fused with deep automatic features. Public ultrasonic-modality-based datasets such as the Breast Ultrasound Images Dataset (BUSI) and the Open Access Database of Raw Ultrasonic Signals (OASBUD) are used for evaluation comparison. The OASBUD data extracted the same features. However, classification was done after feature regularization using the lasso method. The obtained results allow us to propose a computer-aided design (CAD) system for breast cancer identification using ultrasonic modalities.

The choice of cost-effective method of anticorrosive protection of steel structures is an urgent and time consuming task, considering the significant number of protection ways, differing from each other in the complex of technological, physical, chemical and economic characteristics. To reduce the complexity of solving this problem, the author proposes a computational tool that can be considered as a subsystem of computer-aided design and used at the stage of variant and detailed design of steel structures. As a criterion of the effectiveness of the anti-corrosion protection method, the cost of the protective coating during the service life is accepted. The analysis of existing methods of steel protection against corrosion is performed, the possibility of their use for the protection of the most common steel structures is established, as well as the estimated period of effective operation of the coating. The developed computational tool makes it possible to choose the best method of protection of steel structures against corrosion, taking into account the operating conditions of the protected structure and the possibility of using a protective coating.


Author(s):  
S. Minami ◽  
T. Ishida ◽  
S. Yamamoto ◽  
K. Tomita ◽  
M. Odamura

Abstract A concept for the initial stage of the mechanical design and its implementation in the computer-aided design (CAD) are presented. The process of decision making in design is: (1) determining an outline of the whole assembly using a 2-dimensional model that is easy to operate; (2) checking the outline using a 3-dimensional model in which it is easy to identify the spatial relationships; (3) determining details of its sub-assemblies or their components using the 2-dimensional model; and (4) checking the details using the 3-dimensional model. The CAD system must provide consistent relationships through all the steps. For that, following functions are implemented in our prototype system: (1) a 2D and 3D integrated model for consistency between 2- and 3-dimensional shapes, (2) a hierarchical assembly model with dimensional constraints for consistency within an assembly and their components, and (3) a check on constraints for consistency between shapes and designers’ intentions. As a result, the system can provide an environment well fitted to the designers’ decision making process.


Author(s):  
A. M. Andrianov ◽  
G. I. Nikolaev ◽  
I. A. Kashyn ◽  
Yu. V. Kornoushenko ◽  
S. A. Usanov

Computer-aided design of the high-affinity inhibitors of aromatase based on 1,2,4-triazole derivatives was performed by molecular modeling tools. The potential biological activity of the designed compounds was evaluated by molecular docking and quantum chemistry calculations. As a result, six hits that form a coordinate bond with an iron atom of an enzyme hem and effectively interact with its substrate-binding site were identified. The intermolecular interactions appearing in the structural complexes of these ligands with aromatase were analyzed and the enthalpies of their formation were calculated. Based on the data obtained, the identified compounds were suggested to present good scaffolds for the development of novel effective drugs against breast cancer.


Author(s):  
S. N. Trika ◽  
P. Banerjee ◽  
R. L. Kashyap

Abstract A virtual reality (VR) interface to a feature-based computer-aided design (CAD) system promises to provide a simple interface to a designer of mechanical parts, because it allows intuitive specification of design features such as holes, slots, and protrusions in three-dimensions. Given the current state of a part design, the designer is free to navigate around the part and in part cavities to specify the next feature. This method of feature specification also provides directives to the process-planner regarding the order in which the features may be manufactured. In iterative feature-based design, the existing part cavities represent constraints as to where the designer is allowed to navigate and place the new feature. The CAD system must be able to recognize the part cavities and enforce these constraints. Furthermore, the CAD system must be able to update its knowledge of part cavities when the new feature is added. In this paper, (i) we show how the CAD system can enforce the aforementioned constraints by exploiting the knowledge of part cavities and their adjacencies, and (ii) present efficient methods for updates of the set of part cavities when the designer adds a new feature.


Author(s):  
M. J. Jakiela ◽  
P. Y. Papalambros

Abstract System requirements and system design for integrating a production rule program and a computer aided design system are presented. An implementation using a commercially available graphics modeling system is described. A “suggestive mode” interface is programmed as an example with application to design for automated assembly. Initial use of the implementation indicates that encoding production rules is more difficult than with conventional text-only knowledge-based systems, but that this system is a more effective way to use artificial intelligence techniques in design.


Author(s):  
Colin Chong ◽  
Kiyoshi Sogabe ◽  
Kosuke Ishii

Abstract This paper addresses the problem of balancing rotational plastic parts during the early stages of design. The study develops an interactive methodology that uses a solid modeling CAD system and considers injection molding concerns simultaneously with static and dynamic balance. The Transfer Matrix Method evaluates the dynamic characteristics by predicting the approximate critical speed of the part. Design Compatibility Analysis (DCA) checks for injection molding guidelines. Using these evaluation modules interactively, designers can develop a functional and manufacturable part quickly.


Author(s):  
Xun Xu

One of the key activities in any product design process is to develop a geometric model of the product from the conceptual ideas, which can then be augmented with further engineering information pertaining to the application area. For example, the geometric model of a design may be developed to include material and manufacturing information that can later be used in computer-aided process planning and manufacturing (CAPP/CAM) activities. A geometric model is also a must for any engineering analysis, such as finite elopement analysis (FEA). In mathematic terms, geometric modelling is concerned with defining geometric objects using computational geometry, which is often, represented through computer software or rather a geometric modelling kernel. Geometry may be defined with the help of a wire-frame model, surface model, or solid model. Geometric modelling has now become an integral part of any computer-aided design (CAD) system. In this chapter, various geometric modelling approaches, such as wire-frame, surface, and solid modelling will be discussed. Basic computational geometric methods for defining simple entities such as curves, surfaces, and solids are given. Concepts of parametric, variational, history-based, and history-free CAD systems are explained. These topics are discussed in this opening chapter because (a) CAD was the very first computer-aided technologies developed and (b) its related techniques and methods have been pervasive in the other related subjects like computer-aided manufacturing. This chapter only discusses CAD systems from the application point of view; CAD data formats and data exchange issues are covered in the second chapter.


2020 ◽  
Vol 7 (5) ◽  
pp. 603-614 ◽  
Author(s):  
Mutahar Safdar ◽  
Tahir Abbas Jauhar ◽  
Youngki Kim ◽  
Hanra Lee ◽  
Chiho Noh ◽  
...  

Abstract Feature-based translation of computer-aided design (CAD) models allows designers to preserve the modeling history as a series of modeling operations. Modeling operations or features contain information that is required to modify CAD models to create different variants. Conventional formats, including the standard for the exchange of product model data or the initial graphics exchange specification, cannot preserve design intent and only geometric models can be exchanged. As a result, it is not possible to modify these models after their exchange. Macro-parametric approach (MPA) is a method for exchanging feature-based CAD models among heterogeneous CAD systems. TransCAD, a CAD system for inter-CAD translation, is based on this approach. Translators based on MPA were implemented and tested for exchange between two commercial CAD systems. The issues found during the test rallies are reported and analyzed in this work. MPA can be further extended to remaining features and constraints for exchange between commercial CAD systems.


Author(s):  
Ali Fazli ◽  
Behrooz Arezoo ◽  
Mohammad H. Hasanniya

A computer-aided design (CAD) system is developed for automatic process design and finite element (FE) modeling of axisymmetric deep drawn components. Using the theoretical and experimental rules, the system initially designs the process sequence of the component. The obtained process sequence is automatically modeled in abaqus software and the system tests whether failure occurs. The failure is supposed to happen when the fracture is predicted in FE simulation. If failure is predicted, the system changes the appropriate process parameters and carries out the simulation process again until all drawing stages are successful. The system returns the requested parameters for die design such as part geometries in middle stages, drawing forces, blank-holder forces, die, and punch profiles radii. The system is successfully tested for some components found in industry and handbooks.


2004 ◽  
Vol 4 (1) ◽  
pp. 67-78 ◽  
Author(s):  
Li Chen, ◽  
Tingjin Wang, and ◽  
Zhijie Song

Collaborative CAD systems enabling collaboration in computer-aided design processes among distributed designers are gaining more and more attention. Yet, such systems, especially in support of collaborative assembly modeling, are hardly achievable. In an effort to bridge this gap, we are dedicated to developing a collaborative CAD system with aim at 3D assembly modeling. As part of this effort, this paper addresses one function module of the system, a Web-based Product Structure Manager, which enables the Collaborative Product Structure Management (CPSM) in collaborative assembly modeling. In particular, CPSM facilitates product data sharing among distributed designers and supports collaboration in product structure creation and modification. A bench clamp assembly is used as an example to illustrate the Product Structure Manager for supporting collaborative assembly modeling.


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