Antipsychotic Medication-Induced Hyperthermia Leading to Cerebrovascular Accident: A Case Report

Objective: Neuroleptic malignant syndrome (NMS) is a rare but severe side effect of antipsychotic medication. Neutrophil-lymphocyte ratio (NLR) is a simple marker used to measure systemic inflammation. Method: In this case report we explore the relationship of inflammation in the etiology of NMS. In our case involving NMS, although there was no leukocytosis, the NLR was increased up to systemic infection levels. Conclusion: We hypothesized that systemic inflammation may take a role in developing NMS. If so, NLR could be a new marker of NMS that may be able to provide more sensitive results than leukocyte levels.

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Gluteal muscle damage and rhabdomyolysis after olanzapine poisoning: a case report

Journal of International Medical Research ◽

10.1177/03000605211047761 ◽

2021 ◽

Vol 49 (10) ◽

pp. 030006052110477

Author(s):

Guangcai Yu ◽

Siqi Cui ◽

Tianzi Jian ◽

Cece Sun ◽

Longke Shi ◽

...

Keyword(s):

Case Report ◽

Antipsychotic Medication ◽

Paralytic Ileus ◽

Adverse Reactions ◽

Serum Amylase ◽

Critical Role ◽

Elevated Serum ◽

Gluteal Muscle ◽

Antipsychotic Medications ◽

Atypical Antipsychotic Medication

Olanzapine is a widely adopted atypical antipsychotic medication used to manage schizophrenia. Reports show that the incidence rate of adverse reactions to olanzapine is significantly lower than those of other classic antipsychotic medications. However, olanzapine overdose may be associated with severe consequences. Herein, we report a 21-year-old female patient who had taken nearly 700 mg (70 tablets) of olanzapine; she was found after 30 hours. As her condition progressed, she presented with rhabdomyolysis, swelling in the thighs and hips, paralytic ileus, digestive tract hemorrhage, and elevated serum amylase and lipase levels; notably, she recovered after treatment. This intractable case is of great clinical significance and suggests that early-phase hemoperfusion plays a critical role in olanzapine poisoning-related rhabdomyolysis.

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Haemorrhagic Cerebrovascular Accident (CVA) Etiology and Case Report

Acta Medica Transilvanica ◽

10.2478/amtsb-2020-0061 ◽

2020 ◽

Vol 25 (4) ◽

pp. 16-18

Author(s):

Mihaela Luchian ◽

Adriana Săceleanu

Keyword(s):

Case Report ◽

Medical Treatment ◽

Intracerebral Haemorrhage ◽

Vascular Malformation ◽

Cerebrovascular Accident ◽

Intracranial Haemorrhage ◽

Spontaneous Bleeding ◽

The Third ◽

Cerebral Parenchyma ◽

Spontaneous Intracerebral Haemorrhage

Abstract A haemorrhagic cerebrovascular accident refers to a spontaneous bleeding in the cerebral parenchyma, located either supratentorial or infratentorial, that occurs in the absence of a surgical or traumatic cause. The incidence is estimated at 12-15 new cases per 100.000 inhabitants per year. Intracranial haemorrhage is the third most frequent cause of stroke, the vast majority being represented by primary/hypertensive (spontaneous) intracerebral haemorrhage, ruptured saccular aneurysm, a vascular malformation or haemorrhage associated with the use of anticoagulants or thrombolytic agents. A cerebral tomography computer examination is the examination of choice in diagnosis of haemorrhagic CVAs. The treatment can be either therapeutic or surgical, depending on the case, with the consideration that an immediate medical treatment is mandatory for the best odds of recovery.(1)

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Meditation – a two edged sword for psychosis: a case report

Irish Journal of Psychological Medicine ◽

10.1017/ipm.2015.73 ◽

2016 ◽

Vol 33 (4) ◽

pp. 247-249 ◽

Cited By ~ 6

Author(s):

P. Sharma ◽

S. Singh ◽

S. Gnanavel ◽

N. Kumar

Keyword(s):

Case Report ◽

Antipsychotic Medication ◽

Health Benefits ◽

Temporal Correlation ◽

Spiritual Health ◽

Psychotic Symptoms ◽

Beneficial Effects ◽

Precipitating Factor

Meditation is believed to have many health benefits apart from enhancing spiritual health. However, there is evidence that meditation may even lead to psychosis or worsen it in some cases. The aim of this paper is to present a case and discuss the role of meditation as a precipitating factor to psychosis. A 27-year-old male presented with psychotic symptoms with a temporal correlation with meditation. He was then successfully treated with antipsychotic medication and is maintaining well. This case report highlights the possibility that intense meditation could precipitate psychosis in vulnerable individuals. However, there are several beneficial effects of meditation in patients with psychosis if practiced with caution.

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