scholarly journals The Role of Serum Beta h CG in Early Diagnosis and Management Strategy of Ectopic Pregnancy

Author(s):  
Kameswari Surampudi
2020 ◽  
Vol 16 ◽  
Author(s):  
Divya Mirji ◽  
Shubha Rao ◽  
Akhila Vasudeva ◽  
Roopa P.S

Background: Pregnancy of unknown location (PUL) is defined as the absence of intrauterine or extrauterine sac and Beta Human Chorionic Gonadotropin levels (β-HCG) above the discriminatory zone of 1500 mIU/ml. It should be noted that PUL is not always an ectopic; however, by measuring the trends of serum β-HCG, we can determine the outcome of a PUL. Objective: This study aims to identify the various trends β-HCG levels in early pregnancy and evaluate the role of β-HCG in the management strategy. Methods: We conducted a prospective observational study of pregnant women suspected with early pregnancy. Cases were classified as having a pregnancy of unknown location (PUL) by transvaginal ultrasound and ß-HCG greater than 1000 mIU/ml. Expectant management was done until there was a definite outcome. All the collected data were analyzed by employing the chi-square test using SPSS version 20. Results: Among 1200 women who had early first trimester scans, 70 women who fulfilled our criteria of PUL and ß-HCG > 1000 mIU/ml were recruited in this study. In our study, the mean age of the participants was 30±5.6yrs, and the overall mean serum ß-HCG was 3030±522 mIU/ml. The most common outcome observed was an ectopic pregnancy, 47% in our study. We also found the rate of failing pregnancy was 27%, and that of intrauterine pregnancy (IUP) was 25%. Overall, in PUL patients diagnosed with ectopic pregnancy, 9% behaved like IUP, and 4% had an atypical trend in their ß-HCG. Those who had an IUP, 11% had a suboptimal increase in ß-HCG. Conclusion: PUL rate in our unit was 6%. Majority of the outcome of PUL was ectopic in our study. Every case of PUL should be managed based on the initial ß-HCG values, clinical assessments and upon the consent of the patient.


2011 ◽  
Vol 18 (6) ◽  
pp. S156-S157
Author(s):  
A. Shahid ◽  
F. Odejinmi ◽  
L. Baskaran ◽  
N. Deo ◽  
R. Olufowobi ◽  
...  

2010 ◽  
Vol 20 ◽  
pp. S82-S83
Author(s):  
A.A. Solomatina ◽  
A.A. Naumenko ◽  
A.V. Konovalova

2019 ◽  
Vol 104 (5) ◽  
pp. F551-F559 ◽  
Author(s):  
Jacqueline van Druten ◽  
Minesh Khashu ◽  
Sherwin S Chan ◽  
Saeed Sharif ◽  
Hassan Abdalla

Necrotising enterocolitis (NEC) is a leading cause of death and disability in preterm newborns. Early diagnosis through non-invasive investigations is a crucial strategy that can significantly improve outcomes. Hence, this review gives particular attention to the emerging role of abdominal ultrasound (AUS) in the early diagnosis of NEC, its performance against abdominal radiograph and the benefits of AUS use in daily practice. AUS has been used in the diagnosis and management of NEC for a couple of decades. However, its first-line use has been minimal, despite growing evidence demonstrating AUS can be a critical tool in the early diagnosis and management of NEC. In 2018, the NEC group of the International Neonatal Consortium recommended using AUS to detect pneumatosis and/or portal air in preterm NEC as part of the ‘Two out of three’ model. To facilitate widespread adoption, and future improvement in practice and outcomes, collaboration between neonatologists, surgeons and radiologists is needed to generate standard operating procedures and indications for use for AUS. The pace and scale of the benefit generated by use of AUS can be amplified through use of computer-aided detection and artificial intelligence.


2021 ◽  
Vol 11 (7) ◽  
pp. 159-163
Author(s):  
Piyush Dongre ◽  
Tanya Bansal

In surge of the novel corona virus, there is increase in the frequency of fungal infections. Mucormycosis is one of the deep fungal infections which are increasing rapidly in this global pandemic period. Thus the early diagnosis and management is of utmost importance to decline the rate of this fatal infection. The clinical signs and symptoms and the culture reports are strictly considered in the management of oral fungal infection. This review article focuses on the importance of early diagnosis, prevention and management of mucormycosis and the role of the dentist in doing so. Key words: Mucormycosis, diagnosis, management, dentist.


2015 ◽  
Vol 26 (7) ◽  
pp. 1971-1980 ◽  
Author(s):  
Ming-Jue Si ◽  
Shuang Gui ◽  
Qin Fan ◽  
Hong-Xiu Han ◽  
Qian-Qian Zhao ◽  
...  

Radiographics ◽  
1996 ◽  
Vol 16 (4) ◽  
pp. 755-774 ◽  
Author(s):  
M Atri ◽  
C Leduc ◽  
P Gillett ◽  
P M Bret ◽  
C Reinhold ◽  
...  

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