scholarly journals A REVIEW ON PROMISING ANTI-DIABETIC MEDICINAL PLANTS FOR TREATMENT OF DIABETES MELLITUS

2019 ◽  
Vol 10 (3) ◽  
pp. 20-24
Author(s):  
V S Mule ◽  
N S Naikwade
Keyword(s):  
Diabetes Mellitus ◽  
Medicinal Plants ◽  
Treatment Of Diabetes

scholarly journals Glycogen Phosphorylase-a is a Common Target for Anti-Diabetic Effect of Iridoid and Secoiridoid Glycosides

2013 ◽  
Vol 16 (4) ◽  
pp. 530 ◽  
Author(s):  
Hitesh B Vaidya ◽  
Abeer A Ahmed ◽  
Ramesh K Goyal ◽  
Sukhinder K Cheema
Keyword(s):  
Diabetes Mellitus ◽  
Medicinal Plants ◽  
Glycogen Phosphorylase ◽  
Docking Studies ◽  
Chemical Components ◽  
Active Components ◽  
Active Chemical ◽  
Treatment Of Diabetes ◽  
Secoiridoid Glycosides ◽  
Common Target

Purpose. Diabetes mellitus is characterized by hyperglycemia resulting from defects in insulin secretion, action or both. The use of medicinal plants for the treatment of diabetes mellitus dates back from the Ebers papyrus of about 1550 B.C. One of the major problems with herbal drugs is that the active ingredients are not well defined. It is important to know the active components and their molecular interactions which will help to analyze their therapeutic efficacy and also to standardize the product. There are a number of medicinal plants known for their anti-diabetic effect that possess similarities in their active chemical components, e.g. iridoid and secoiridoid glycosides. Methods. In this study, we have compared the structure of various iridoid and secoiridoid glycosides to design a novel pharmacophore. We further developed a structure-activity relationship for the inhibition of glycogen phosphorylase-a. Conclusion. By using docking studies, we are proposing, for the first time, that inhibition of glycogen phosphorylase-a activity is a common target for iridoids and secoiridoids to elicit anti-diabetic effects. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

Antidiabetic Activity (Anti-Hyperglycemic Activity, Anti-Hyperlipidemic Activity)/Agents From Medicinal Plants

2020 ◽  
pp. 25-48
Author(s):  
Manish Singh Sansi ◽  
Daraksha Iram ◽  
Kapil Singh Narayan ◽  
Sandeep Kumar ◽  
Om Prakash ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Secretion ◽  
Medicinal Plants ◽  
Insulin Receptor ◽  
Antidiabetic Activity ◽  
Insulin Deficiency ◽  
Receptor Function ◽  
Synthetic Drugs ◽  
Treatment Of Diabetes ◽  
Insulin Receptor Kinase

Diabetes mellitus (DM) is a chronic disease caused by inherited or acquired deficiency in insulin secretion and by decreased insulin secretion by the organ. Insulin deficiency causes the DM. Synthetic drugs are widely used in the treatment of diabetes, but they have some side effects. The antihyperglycemic and antihyperlipedemic effects of the plants are related to their ability to maintain pancreatic function. Medicinal plants constituents such as glycosides, alkaloids, terpenoids, and flavonoids mitigate DM. B. ciliata inhibits the α-glucosidase and α-amylase. Cinnamon extracts improve insulin receptor function by activating insulin receptor kinase and inhibiting insulin receptor phosphatase, which lead to an increase in insulin sensitivity. Morinda lucida also had the highest antioxidant activity, and it also inhibited the α-glucosidase. Many plants have also been shown to antihyperlipedemic effects. Finally, it can be concluded that medicinal plants have that ability to treat or prevent DM.

scholarly journals Medicinal plants for treatment of diabetes mellitus

2000 ◽  
Vol 15 (S1) ◽  
pp. 169-177 ◽  
Author(s):  
R. Shukia ◽  
S. B. Sharma ◽  
D. Puri ◽  
K. M. Prabhu ◽  
P. S. Murthy
Keyword(s):  
Diabetes Mellitus ◽  
Medicinal Plants ◽  
Treatment Of Diabetes

Medicinal plants in the supplementary treatment of diabetes mellitus

2011 ◽  
Vol 5 (7) ◽  
pp. 1738
Author(s):  
Manuelle Arias Piriz ◽  
Marcos Klering Mesquita ◽  
Teila Ceolin ◽  
Caroline Vasconcellos Lopes ◽  
Rita Maria Heck
Keyword(s):  
Diabetes Mellitus ◽  
Medicinal Plants ◽  
Rio Grande ◽  
Ethics Committee ◽  
Rio Grande Do Sul ◽  
Treatment Of Diabetes ◽  
Supplementary Treatment ◽  
Positive Results ◽  
De Medicina ◽  
Structured Questionnaire

ABSTRACTObjective: to list the main medicinal plants used by ecological farmers from southern Rio Grande do Sul in the supplementary treatment of diabetes mellitus. Method: it was performed a study with qualitative approach of  exploratory and descriptive kind. The study subjects were farmers who sell their products at the ecological fair of Pelotas. Data were collected using semi-structured questionnaire. The interviews were recorded with consent of farmers and the plants were georeferenced and photographed for taxonomic  identification. The project was approved by the Ethics Committee of the Faculty of Medicine at 072/2007 opinion. Results: ten plants were mentioned in the treatment of diabetes mellitus. According to the literature, six of them had positive results in animals or humans as hypoglycemiants, and the other plants are indicated to treat various other symptoms. Conclusion: medicinal plants can act as an adjuvant of the medicamentous therapy in reducing glicemy of the disease carriers, taking into account the legal and safe precepts for using and importance of nurses in advising on the correct use of these therapies. Descriptors: phytotherapy; rural health; diabetes mellitus; nursing.RESUMOObjetivo: listar as principais plantas medicinais utilizadas por agricultores ecológicos do sul do Rio Grande do Sul no tratamento complementar do diabetes mellitus. Método: foi realizado um estudo de abordagem qualitativa do tipo exploratório e descritivo. Os sujeitos foram agricultores que comercializam seus produtos na feira ecológica de Pelotas. Os dados foram coletados utilizando questionário semi-estruturado. As entrevistas foram gravadas com consentimento dos agricultores e as plantas georreferenciadas e fotografadas para identificação taxonômica. O projeto foi aprovado pelo Comitê de Ética da Faculdade de Medicina por meio do parecer 072/2007. Resultados: foram citadas dez plantas utilizadas no tratamento de diabetes mellitus. De acordo com a literatura, seis delas obtiveram resultados positivos em animais ou humanos como hipoglicemiantes, as demais são indicadas para tratar outros diversos sintomas. Conclusão: as plantas medicinais podem atuar como adjuvantes da terapia medicamentosa na redução da glicemia de portadores da doença, levando-se em conta os preceitos legais e seguros da utilização e a importância dos enfermeiros no aconselhamento sobre o correto uso destas terapias. Descritores: fitoterapia; saúde da população rural; diabetes mellitus; enfermagem. RESUMENObjetivo: elaborar una lista de las principales plantas medicinales utilizadas por los agricultores ecológicos del sur de Río Grande do Sul en el tratamiento suplementario de la diabetes mellitus. Método: se realizó un estudio com um abordaje cualitativo de naturaleza exploratoria y descriptiva. Los sujetos de estudio fueron los agricultores que venden sus productos en la feria ecológica de Pelotas. Los datos fueron recolectados a través de cuestionario semi-estructurado. Las entrevistas fueron grabadas con el consentimiento de los agricultores y las plantas georeferenciados y fotografiados para su identificación taxonómica. El proyecto fue aprobado por el Comité de Ética de la Facultad de Medicina de la opinión 072/2007. Resultados: diez plantas fueron mencionadas en el tratamiento de la diabetes mellitus. De acuerdo con la literatura, seis de ellos tuvieron resultados positivos en animales o seres humanos como agentes hipoglucemiantes, los otros están indicados para el tratamiento de varios otros síntomas. Conclusión: las plantas medicinales pueden actuar como adyuvante a la terapia medicamentosa en la reducción de la glicemia en los portadores de la enfermedad, teniendo en cuenta los preceptos legales y seguros de la iutilización y la importancia de las enfermeras en el aconsejamiento sobre el correcto uso de estas terapias. Descriptores: fitoterapia; salud rural; diabetes mellitus; enfermería.

scholarly journals A REVIEW ON ROLE OF ANTIOXIDANTS IN DIABETES

2018 ◽  
Vol 11 (2) ◽  
pp. 48 ◽  
Author(s):  
Deepa Rajendiran ◽  
Subbulakshmi Packirisamy ◽  
Krishnamoorthy Gunasekaran
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Metabolic Disease ◽  
Medicinal Plants ◽  
Major Part ◽  
Review Article ◽  
Hypoglycemic Activity ◽  
Antioxidants Activity ◽  
Treatment Of Diabetes

 Diabetes mellitus is a chronic metabolic disease. Oxidative stress plays a major part in the pathogenesis of diabetes. Supplementation with antioxidants and the medicinal plants which possess antioxidants activity have been reported their hypoglycemic activity. The antioxidants are used to treat and reduce the complication of diabetes mellitus. The diet supplementations of antioxidants vitamins are beneficial in the treatment of diabetes. This review article was summarizing the role of antioxidants in diabetes mellitus.

scholarly journals A Review on Anti-diabetic Activity of Medicinal Spices

2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Ramya P ◽  
Lavanya Krishnadhas
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Medicinal Plants ◽  
Human Body ◽  
Metabolic Disorder ◽  
Well Being ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Treatment Of Diabetes

Diabetes mellitus is a common metabolic disorder in which the human body does not produce insulin hormone, this leads to the increase in blood glucose levels. Diabetes infects more than 387 million individuals globally, posing a significant threat to both personal well-being and global economies. Normally, medicinal plants are highly used for the treatment of diabetes mellitus but some spices also have the efficiency to treat diabetes. Still, spices which we are using as ingredients plays important role in foods also have the ability to treat diabetes. This article describes the anti-diabetic activity of those medicinal spices.

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