Research on a diagnostic model of deep learning-based pneumonia using defense medical data

2021 ◽  
Vol 22 (3) ◽  
pp. 509-517
Author(s):  
Tae-Hwan Lim ◽  
Seung-Chul Han
Author(s):  
Naresh Sammeta ◽  
Latha Parthiban

AbstractIn recent times, advanced developments in healthcare sector result in the generation of massive amounts of electronic health records (EHRs). EHR system enables the data owner to control his/her data and share it with designated people. The vast volume of data in the healthcare system makes it difficult for data to ensure security and diagnostic processes. To resolve these issues, this paper develops a new hyperledger blockchain enabled secure medical data management with deep learning (DL)-based diagnosis (HBESDM-DLD) model. The presented model involves distinct stages of operations such as encryption, optimal key generation, hyperledger blockchain-based secure data management, and diagnosis. The presented model allows the user to control access to data, permit the hospital authorities to read/write data, and alert emergency contacts. For encryption, SIMON block cipher technique is applied. At the same time, to improve the efficiency of the SIMON technique, a group teaching optimization algorithm (GTOA) is applied for the optimal key generation of the SIMON technique. Moreover, the sharing of medical data takes place using multi-channel hyperledger blockchain that utilizes a blockchain for storing patient visit data and for the medical institutions to record links for the EHRs saved in external databases. Once the data are decrypted at the receiving end, finally, variational autoencoder (VAE)-based diagnostic model is applied to detect the existence of the diseases. The performance validation of the HBESDM-DLD model takes place on benchmark medical dataset and the results are inspected under various performance measures. The experimental results proves that the HBESDM-DLD methodology is superior to state-of-the-art methods.


2021 ◽  
Vol 15 (8) ◽  
pp. 898-911
Author(s):  
Yongqing Zhang ◽  
Jianrong Yan ◽  
Siyu Chen ◽  
Meiqin Gong ◽  
Dongrui Gao ◽  
...  

Rapid advances in biological research over recent years have significantly enriched biological and medical data resources. Deep learning-based techniques have been successfully utilized to process data in this field, and they have exhibited state-of-the-art performances even on high-dimensional, nonstructural, and black-box biological data. The aim of the current study is to provide an overview of the deep learning-based techniques used in biology and medicine and their state-of-the-art applications. In particular, we introduce the fundamentals of deep learning and then review the success of applying such methods to bioinformatics, biomedical imaging, biomedicine, and drug discovery. We also discuss the challenges and limitations of this field, and outline possible directions for further research.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Steven A. Hicks ◽  
Jonas L. Isaksen ◽  
Vajira Thambawita ◽  
Jonas Ghouse ◽  
Gustav Ahlberg ◽  
...  

AbstractDeep learning-based tools may annotate and interpret medical data more quickly, consistently, and accurately than medical doctors. However, as medical doctors are ultimately responsible for clinical decision-making, any deep learning-based prediction should be accompanied by an explanation that a human can understand. We present an approach called electrocardiogram gradient class activation map (ECGradCAM), which is used to generate attention maps and explain the reasoning behind deep learning-based decision-making in ECG analysis. Attention maps may be used in the clinic to aid diagnosis, discover new medical knowledge, and identify novel features and characteristics of medical tests. In this paper, we showcase how ECGradCAM attention maps can unmask how a novel deep learning model measures both amplitudes and intervals in 12-lead electrocardiograms, and we show an example of how attention maps may be used to develop novel ECG features.


2021 ◽  
Author(s):  
Birgid Schömig-Markiefka ◽  
Alexey Pryalukhin ◽  
Wolfgang Hulla ◽  
Andrey Bychkov ◽  
Junya Fukuoka ◽  
...  

AbstractDigital pathology provides a possibility for computational analysis of histological slides and automatization of routine pathological tasks. Histological slides are very heterogeneous concerning staining, sections’ thickness, and artifacts arising during tissue processing, cutting, staining, and digitization. In this study, we digitally reproduce major types of artifacts. Using six datasets from four different institutions digitized by different scanner systems, we systematically explore artifacts’ influence on the accuracy of the pre-trained, validated, deep learning-based model for prostate cancer detection in histological slides. We provide evidence that any histological artifact dependent on severity can lead to a substantial loss in model performance. Strategies for the prevention of diagnostic model accuracy losses in the context of artifacts are warranted. Stress-testing of diagnostic models using synthetically generated artifacts might be an essential step during clinical validation of deep learning-based algorithms.


2021 ◽  
Vol 11 (2) ◽  
pp. 760
Author(s):  
Yun-ji Kim ◽  
Hyun Chin Cho ◽  
Hyun-chong Cho

Gastric cancer has a high mortality rate worldwide, but it can be prevented with early detection through regular gastroscopy. Herein, we propose a deep learning-based computer-aided diagnosis (CADx) system applying data augmentation to help doctors classify gastroscopy images as normal or abnormal. To improve the performance of deep learning, a large amount of training data are required. However, the collection of medical data, owing to their nature, is highly expensive and time consuming. Therefore, data were generated through deep convolutional generative adversarial networks (DCGAN), and 25 augmentation policies optimized for the CIFAR-10 dataset were implemented through AutoAugment to augment the data. Accordingly, a gastroscopy image was augmented, only high-quality images were selected through an image quality-measurement method, and gastroscopy images were classified as normal or abnormal through the Xception network. We compared the performances of the original training dataset, which did not improve, the dataset generated through the DCGAN, the dataset augmented through the augmentation policies of CIFAR-10, and the dataset combining the two methods. The dataset combining the two methods delivered the best performance in terms of accuracy (0.851) and achieved an improvement of 0.06 over the original training dataset. We confirmed that augmenting data through the DCGAN and CIFAR-10 augmentation policies is most suitable for the classification model for normal and abnormal gastric endoscopy images. The proposed method not only solves the medical-data problem but also improves the accuracy of gastric disease diagnosis.


2020 ◽  
Vol 1 (1) ◽  
pp. 015009 ◽  
Author(s):  
Chang Min Hyun ◽  
Kang Cheol Kim ◽  
Hyun Cheol Cho ◽  
Jae Kyu Choi ◽  
Jin Keun Seo

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Guo-Ping Liu ◽  
Jian-Jun Yan ◽  
Yi-Qin Wang ◽  
Wu Zheng ◽  
Tao Zhong ◽  
...  

In Traditional Chinese Medicine (TCM), most of the algorithms used to solve problems of syndrome diagnosis are superficial structure algorithms and not considering the cognitive perspective from the brain. However, in clinical practice, there is complex and nonlinear relationship between symptoms (signs) and syndrome. So we employed deep leaning and multilabel learning to construct the syndrome diagnostic model for chronic gastritis (CG) in TCM. The results showed that deep learning could improve the accuracy of syndrome recognition. Moreover, the studies will provide a reference for constructing syndrome diagnostic models and guide clinical practice.


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