In vitro Antioxidant Activity of Salacia lehmbachii Ethanol Root Bark Extract

2017 ◽  
Vol 18 (4) ◽  
pp. 1-6
Author(s):  
Godwin Akuodor ◽  
Grace Essiet ◽  
Augustine Essien ◽  
Francis Udoh ◽  
Donald Ogiji ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Bark Extract ◽  
Root Bark ◽  
In Vitro Antioxidant Activity

scholarly journals Evaluation of In-Vitro Antioxidant Activity of Root Bark Extracts of Ventilago Maderspatana Gaertn

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1636-1640
Author(s):  
Manish Deshmukh ◽  
Ashish Budhrani ◽  
Upendra Gandagule ◽  
Sanjay Nagdev ◽  
Mayur Bhurat ◽  
...  
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Bark Extract ◽  
Root Bark ◽  
Anti Oxidant ◽  
Biomedical Potential ◽  
Oxide Inhibition ◽  
In Vitro Antioxidant Activity

Ventilago maderspatana Gaertn. is a plant having enormous biomedical potential. It is a plant in the Indian system of medicine having a plethora of properties and applications and The root barks powder of Ventilago maderspatana Gaertn.  have many properties and applications like it are used as a stomachic, tonic, carminative, stimulant. It is also useful in the treatment of weakness and fever. For further investigations of activities like anti-oxidant activity, In-vitro  anti-oxidant studies were done on root bark extracts of Ventilago maderspatana Gaertn. (Family Rhamnaceae) by using standard methods like Lipid peroxidation Assay, Estimation of total anti-oxidant capacity (TAC), Hydroxyl radical scavenging activity, Nitric oxide inhibition radical activity by p-Nitroso dimethyl aniline method, and ABTS Radical scavenging method. The root barks of plant Ventilago maderspatana Gaertn. Were subjected to cold maceration process in 3-liter Round bottom flask using ethanol and distilled water and nature and yield was noted and stored at 40C in the refrigerator until further use and both the extracts were labelled as Ventilago maderspatana Gaertn. Root Bark aqueous (VMRBA) and Ventilago maderspatana Gaertn. Root Bark Ethanolic (VMRBE) for convenient identification. Ethanolic extract of Root Bark showed the more potent anti-oxidant activity than aqueous Root Bark extract of Ventilago maderspatana Gaertn.

scholarly journals In–vitro antioxidant activity of crataeva magna lour. dc bark extract

2012 ◽  
Vol 2 ◽  
pp. S846-S848 ◽  
Author(s):  
N Sridhar ◽  
S. Manisha Mishra ◽  
S. Venkataraman
Keyword(s):  
Antioxidant Activity ◽  
Bark Extract ◽  
In Vitro Antioxidant Activity

Evaluation of in vitro Antioxidant Activity and Total Phenolic Content of Methanol Bark Extract of Mimusops elengi

2011 ◽  
Vol 1 (2) ◽  
pp. 62-71 ◽  
Author(s):  
K. Srinivasa Rao ◽  
Prameela Rani Munjuluri ◽  
B.V.V. Ravi Kumar ◽  
Nargesh K. Keshar
Keyword(s):  
Antioxidant Activity ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Bark Extract ◽  
Total Phenolic ◽  
Mimusops Elengi ◽  
In Vitro Antioxidant Activity

scholarly journals Comparative Studies On The Phytochemical Screening And In Vitro Antioxidant Activities Of Aqueous Extracts Of Garcinia Kola Stem And Root Barks

2020 ◽  
Vol 1 (3) ◽  
Author(s):  
Philip O. Amira ◽  
Adebayo S. Daramola ◽  
Ayobioloja A. Philomina ◽  
Salau A. Ibukun
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Properties ◽  
Stem Bark ◽  
Bark Extract ◽  
Root Bark ◽  
Aqueous Extracts ◽  
Dpph Assay ◽  
Garcinia Kola ◽  
Total Antioxidant

Phytochemicals are natural chemicals of plant origin that have implicated in anti-disease mechanism. Antioxidant are insulator of the process of the oxidation even at relatively small concentration and this have diverse physiological role in the body. They are naturally occurring in the medicinal plants, vegetables, leaves and roots that have defense mechanism and protect from various diseases as well inhibit, or delay the oxidation of other molecules by inhibiting the initiation or propagation of oxidizing chain reaction. Garcinia kola is a tropical flowering plant grown mainly in West and Central Africa. Garcinia kola is known for its anti-inflammatory and antioxidant properties. Therefore, comparative studies on the phytochemical screening and in vitro antioxidant activity on aqueous extracts of stem and root of Garcinia kola were investigated to assess their antioxidant properties in different antioxidant property determination assays. Aqueous extracts of Garcinia kola stem and root bark revealed the presence of tannins, resin, saponins, flavonoids, phenols, carbohydrates and alkaloids. In addition, the aqueous root bark extract of the plant contained phlobatanins and sterols while its stem bark aqueous extract contained terpenoids. The IC50 (μg/ml) values of the stem bark extract were 108.35 ± 7.70, 122.81 ± 3.98, 0.20 ± 0.01, 0.16 ± 0.01 and 0.43 ±0.01 for total antioxidant capacity (AAE), ferric reducing antioxidant activity (AAE), diphenyl picryl hydrazyl (DPPH) assay, nitric oxide (NO) scavenging activity and metal chelating activity respectively. On the other hand, the IC50 (μg/ml) values of the root bark extract were 31.54 ± 2.72, 30.50 ± 0.96, 2.26 ± 0.13, 4.36 ± 0.52 and 0.75 ± 0.04 for total antioxidant capacity (AAE), ferric reducing antioxidant activity (AAE), diphenyl picryl hydrazyl (DPPH) assay, nitric oxide (NO) scavenging activity and metal chelating activity respectively. Consequently, both the stem bark and root bark extracts generally exhibited remarkable in vitro antioxidant properties with respect to the parameters investigated.

scholarly journals TLC profiling and antioxidant activity of phenolic compound from Sterculia oblongata bark extract

2019 ◽  
Vol 11 (1) ◽  
pp. 44-48 ◽  
Author(s):  
TRI MURNINGSIH ◽  
PRAPTIWI PRAPTIWI ◽  
LIANA LIANA ◽  
AHMAD FATHONI
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Compound ◽  
Total Phenolic Content ◽  
Methanol Extract ◽  
Phenolic Content ◽  
Bark Extract ◽  
Total Phenolic ◽  
Β Carotene ◽  
In Vitro Antioxidant Activity

Abstract. Murningsih T, Praptiwi, Liana, Fathoni A. 2019. TLC profiling and antioxidant activity of phenolic compound from Sterculia oblongata bark extract. Nusantara Bioscience 11: 44-48. In the present study, we investigated the total phenolic content and in- vitro antioxidant activity of Sterculia oblongata. Total phenolic content (TPC) of the methanol extract was examined by Folin-Ciocalteu reagent and gallic acid as standard. The in-vitro antioxidant activity was performed by DPPH free radical scavenging activity and β-carotene bleaching assay. The result showed that the TPC of methanol extract was the highest (P<0.05) compared to other extracts. There is a positive and significantly very high Pearson’s correlation between antioxidant activity index (AAI) and TPC (r = 0.996). A negative and significantly high Pearson’s correlation was obtained between IC50 value and TPC (r = -0.885). The result of β-carotene bleaching assay showed that the rate of the decreased antioxidant activity of S.oblongata extract was lower than that of β-carotene/linoleic acid. The results suggest that the extract of S. oblongata can be used as a natural antioxidant. However, further investigation to isolate and identify the chemical compounds responsible for antioxidant was needed

scholarly journals In Vitro Antioxidant Activity and Effect of Parkia biglobosa Bark Extract on Mitochondrial Redox Status

2014 ◽  
Vol 7 (4) ◽  
pp. 202-210 ◽  
Author(s):  
Kayode Komolafe ◽  
Tolulope Mary Olaleye ◽  
Olaposi Idowu Omotuyi ◽  
Aline Augusti Boligon ◽  
Margareth Linde Athayde ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Redox Status ◽  
Bark Extract ◽  
Parkia Biglobosa ◽  
In Vitro Antioxidant Activity

scholarly journals Evaluation of Andira inermis stem bark extract for hypoglycaemic and antioxidant effects’

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Maxwell Osaronowen Egua ◽  
Florence Chimezie Nwinyi ◽  
Ode Julius Okwoche ◽  
Onakpa Micheal Monday ◽  
Akande Motunrayo Ganiyat ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Blood Glucose ◽  
Acute Toxicity ◽  
Methanolic Extract ◽  
Stem Bark ◽  
Bark Extract ◽  
Albino Rats ◽  
Stem Bark Extract ◽  
In Vitro Antioxidant Activity

Abstract Background The aqueous methanolic extract of Andira inermis(A. inermis) stem bark was screened for phytochemical constituents, antioxidant activity, acute oral toxicity, and preliminary prophylactic normoglycaemic test and effect on Oral Glucose Tolerance in albino rats. Methods Andira inermis was double macerated and extracted with 80% methanol. Phytochemical analysis and acute toxicity were performed using standard methods. The extract was screened for in vitro antioxidant activity using Ferric Reducing/Antioxidant Power (FRAP) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging spectrophotometric assays. Prophylactic control of glucose was evaluated in normoglycaemic and glucose-challenged albino rats. Graded test doses (100–400 mg/kg body weight) of the extract were used in the investigation. The effects observed were compared with that of glibenclamide (0.2 mg/kg) and distilled water control groups. Results The stem bark extract of A. inermis was found to contain saponins, terpenes, tannins, steroids, flavanoids, anthraquinones, carbohydrates and alkaloids. The extract was found to have a significant in vitro antioxidant activity in both methods. The oral acute toxicity study showed the extract had LD50 greater than 5000 mg/kg. The extract significantly (p ≤ 0.05) reduced blood glucose levels in normoglycaemic animal model (the control group seen to have − 5.6(− 8.7%) poor glucose handling; and the glibenclamide& extract treatment group (100 mg/kg) to positively reduce blood glucose 14.8(26.8%) & 16.4(25.9%) respectively). The glucose challenged test, from the 1st hour, showed − 57.4(− 89.4%),-26.8(− 33.8%),-23.8(− 26.3%),-12.8(− 13.9%) and − 9.8(− 10.4%) for the vehicle control, glibenclamide (positive control), and the 100, 200 & 400 mg/kg extract treatment groups respectively. The extract showed mild hypoglycemic effect in the results recorded, up to the 4th hour. Conclusion The results of this study elucidated that the aqueous methanolic extract of Andira inermis stem bark possessed potent antioxidant phyto-constituents with potential hypoglycaemic effects that could be explored for therapeutic use worldwide following isolation and characterization of the bioactive principles. And the results also authenticate the folklore use of the plant.

In vitro antioxidant activity and tannin content of Echium italicum L.

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
N Niciforovic ◽  
S Solujic ◽  
V Mihailovic ◽  
D Pavlovic-Muratspahic
Keyword(s):  
Antioxidant Activity ◽  
Tannin Content ◽  
In Vitro Antioxidant Activity
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