Lembosia mimusopis sp. nov. from Thailand

A novel species Lembosia mimusopis is introduced with evidence from morpho-molecular characterization. It was collected from the leaves of Mimusops elengi in Chiang Rai Province, Thailand. The new species is unique in having a mucilaginous sheath surrounding its immature ascospores. LSU sequence analyses phylogenetically support separation of this species from other Lembosia species.

Extraction yield, antioxidant activity and total phenolic content of Mimusops elengi L. fruit

Mimusops elengi L. fruit or known as Bakul fruit is believed to have a lot of benefit due to its flavonoid group compound that can have antioxidant effects. This study aimed to determine the effect of temperature and ratio between material and solvent in the extraction process on the antioxidant activity and content of phenolic compounds in Mimusops elengi L. fruit extract. This research used factorial completely randomized design with 2 factors : extraction temperature (45¼C, 60¼C, and 75¼C) and ratio of the material and solvent (1:4, 1:6, and 1:8) with 3 replications. The extraction yield, total phenolic contents and antioxidant activity of Mimusops elengi L. fruit extract were examined. Furthermore, the application of extraction temperature in 75¼C with ratio 1:8 material to solvent (w/v) has the highest extraction yield, total phenolic contents and antioxidant activity compared to others treatments.

Hepatoprotective Potential of Mimusops elengi L leaf Extracts against Paracetamol Induced Hepatotoxicity in Rats

Many traditional systems of medicines employ herbal drugs for the hepatoprotection. The aim of the study is to investigate the hepatoprotective activity of Mimusopselengi L leaf extracts extracts against paracetamol induced hepatotoxicity. However, herbal plants are the windfall for the humankind providing solution for most of the wellness breakdowns. Mimusopselengi L is one of such plants with enormous therapeutic and nutraceutical potencies. The main aspiration of the current investigation is to evaluate the hepatoprotective ability of methanolic and aqueous extract of Mimusopselengi L leaves against paracetamol induced hepatotoxicity using wistar rats through biochemical parameters and histopathological findings. The phytochemical screening was carried on the leaves extracts of Mimusopselengi L revealed the presence of some active ingredients such as Alkaloids, Tannins, Sponginess, Phenols, glycosides, steroids, terpenoids and flavonoids. Leaves of Mimusopselengi L was successively ethylacetate fraction with methanolic and aqueous extract against paracetamol (2 ml/kg.p.o) induced hepatotoxicity using Standard drug Liv 52 (5 ml/kg). There was a significant changes in biochemical parameters (increases in serum glutamate pyruvate transaminase (SGPT), Serum glutamate oxaloacetate transaminase (SGOT), alanine phosphatase (ALP), serum bilirubin in paracetamol treated rats, which were restored towards normalization in Mimusopselengi L methanolic and aqueous extract (200 mg/kg and 200 mg/kg) treated animals. Thus, the present study ascertains that the leaf extract of Mimusopselengi L possesses significant hepatoprotective activity.

Study on the Implementation of the Green City Development Program (PK2H) through Optimizing Green Open Space (RTH) in Ilir Barat I District, Palembang City

This study aims to analyze the development, utilization, supervision, and control of the green open space program in Ilir Barat I Sub-District, Palembang. This study was conducted in, Ilir Barat I Sub-District, Palembang city.October 2019 to December 2019. On this research used descriptive qualitative methods and analysis of vegetation (Anveg) by using and purposive sampling. Based on the analysis,The Sub-District of Ilir Barat I has a Green Open Space (RTH) covering an area of 101,389 m2 with a percentage of 0.51%. The area of it does not meet the minimum area of green space based on Law No. 26 of 2007 in article 29 paragraph (2) of 30% and has met the requirements of article 29 paragraph (3) of 20%. With the distribution of green open space is the Puncak Sekuning TPU with an area of 40,000 m² with a percentage of 0.20%.The green space location with the smallest area in the stadium of Bumi Sriwijaya has a green space of 1,627 m² with a percentage of 0.01%. The area of green space in the District of Ilir Barat I Palembang based on the results of the study was 101,389 m², while the area of it based on Palembang PRKP data in the Sub-District of Ilir Barat I of Palembang City was 96,166 m². Researcher measurement data has a difference of 5,223 m² with data from the Palembang City PRKP Service. Angsana tree (Pterocarpus indicus), The highest number of tree in green line (road side) is Trembesi (Albizia saman) while in median road is Tanjung (Mimusops elengi).

Phytochemical Assessment of Mimusops elengi Linn. Unripe fruits Methanol extracts using Modern Analytical Technique

Mimusops elengi Linn. is a plant with high medicinal and commercial value. Although several secondary metabolites have been reported from different species of this plant, there has been not much information available on the complete profile of phytochemical constituents in Mimusops elengi Linn. The HPTLC fingerprinting of methanol extract showed 6 peaks having maximum Rf values 0.10, 0.27, 0.34, 0.51, 0.72, and 0.80 at 254nm. The same extract showed 3 peaks having maximum Rf value 0.25, 0.29 and 0.49 at 366 nm. This study applies Gas chromatography-Mass spectrometry technique to determine the possible chemical components in the methanol extract of Mimusops elengi Linn. Unripened fruits reports for the first time most extensive profile of the plant. The determination and identification of bioactive chemical compounds is established and based on the peak area, retention time molecular weight, and molecular formula. GC-MS analysis of Mimusops elengi Linn. revealed the existence of the 2,2’ Methylenebis [3,4,6-trichloroanisole] which was found to be major component followed by Z-1,9-Hexadecadiene, Cyclopentaneundecanoic-acid, 4-Methyloctanoic acid and E-10-Dodecen-1-ol propionate. The results obtained may be helpful to the further study of pharmacological action for their promising utilization as therapeutic agents.

Investigating the Antioxidant and Cytocompatibility of Mimusops elengi Linn Extract over Human Gingival Fibroblast Cells

Background—chlorhexidine (CHX) is most commonly used as a chemical plaque control agent. Nevertheless, its adverse effects, including teeth discoloration, taste alteration and calculus build-up, limit its use and divert us to medicinal herbs. The purpose of the study was to evaluate the phytochemical composition, antioxidant potential, and cytotoxic effects of Mimusops elengi Linn extract (ME) over normal human cultured adult gingival fibroblasts (HGFs). Methods—in vitro phytochemical screening, total flavonoid content, antioxidant potential by DPPH and Nitric Oxide (NO) radical scavenging activity, and cytotoxic effects of ME extracts over HGF were explored. The viability of HGF cells was determined using 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide (MTT), neutral red uptake, and trypan blue assay after treatment with different concentrations of CHX and ME (0.3125 to 10 µg/mL). Results—ME showed some alkaloids, glycosides, saponins and flavonoids exhibited relatively moderate-to-good antioxidant potential. Increasing the concentration of CHX and ME from 0.3125 to 10 µg/mL reduced cell viability from 29.71% to 1.07% and 96.12% to 56.02%, respectively. At higher concentrations, CHX reduced the viability of cells by 52.36-fold compared to ME, revealed by MTT assay. At 10 µg/mL concentration, the mean cell viability of CHX and ME-treated cells was 2.24% and 57.45%, respectively, revealed by a neutral red assay. The viability of CHX- and ME-treated HGF cells estimated at higher concentrations (10 µg/mL) using trypan blue assay was found to be 2.18% and 47.36%, respectively. A paired t-test showed significance (p < 0.05), and one-way ANOVA difference between the mean cell viability of CHX- and ME-treated cells at different concentrations. One-way ANOVA confirmed the significant difference between the viability of CHX- and ME-treated cells. Conclusions—The cytoprotective and antioxidant effects of ME emphasize its potential benefits. Therefore, it could emerge as a herbal alternative and adjunct to conventional oral hygiene methods, that can diminish periodontal tissue destruction.

Evaluation of plant species diversity in the road dividers of Dhaka City

The present study aims to evaluate the present status of plant species diversity in the road dividers of Dhaka city. A total of 90 plant species under 73 genera and 42 families have been recorded from the road dividers of Dhaka city. Analysis showed that among the 90 species, the most abundant plant species in the road divider are Mimusops elengi (Bakul) Polyalthia longifolia (Debdaru), Leucaena leucocephala (Epil-epil), Tabernaemontana divaricata (Togor) and Swietenia mahagoni (Mahagoni). In case of dominant analysis based important value index showed that Mimusops elengi is the top dominant plant species followed by Polyalthia longifolia, Leucaena leucocephala, Tabernaemontana divaricata and Swietenia mahagoni respectively. These plant species have also showed the higher relative density, relative frequency and relative abundance. The percentage of native and exotic species was found here 44% and 56%, respectively. Most abundant and dominant plant species in the road dividers are exotics including Mimusops elengi,Polyalthia longifolia, Leucaena leucocephala and Swietenia mahagoni. Species diversity value was found higher in Hatirjeel site whereas lowest in Baridhara- Badda site. A number of recommendations are made based on the present results for the management of plant species diversity in the road dividers of Dhaka city. Some recommended native plant species for plantation according to the width and soil depth in the road dividers are Cassia fistula, Holarrhena pubescens, Firmiana colorata, Shorea robusta, Miliusa valutina, Butea monosperma, Alstonia scholaris, Toona ciliata, Ficus racemosa, Bombax ceiba, Woodfordia fruticosa, Melastoma malabathricum, Sterculia villosa, Grewia microcos, Syzygium cumini, Tabernaemontana divaricata, Ixora coccinea, Terminalia bellirica, Terminalia arjuna and also native seasonal flowers. Bangladesh J. Plant Taxon. 28(1): 141-154, 2021 (June)