scholarly journals Evalution of Human Amniotic Membrane in Extraction Socket for Faster Wound Healing

Author(s):  
S. P. Indra Kumar ◽  
Afrose Fathima ◽  
S. Deepika ◽  
R. J. Aravind ◽  
T. Kavin ◽  
...  

Background: Preservation of extraction site with grafting shall always produce better healing results. Various materials have been used for this process and each material has its unique benefits and properties. Few such materials are Simvastatin, Bone ceramic, oxidized cellulose, bone allograft, etc. In this given study, 10 patients were placed Human amniotic membrane in their extracted socket and the results were reviewed after 7days, 14 days, 21 days, 1 month, 3 month and 6 month. Materials and Methods: The samples are voluntary and those patients with no clinical abnormalities were included. Human amniotic membrane is received from Tata Memorial Hospital, Mumbai. Ten patients who reported to Department of OMFS were selected for the augmentation procedure. After extraction, the Human amniotic membrane was placed in the extracted socket and secured with sutures. Post-operative visits scheduled after 7days, 14 days, 21 days, 1 month, 3 month and 6 month intervals for analyzing the he.0aling property of amnion in the augmented extraction sockets. Results: The results of this study have shown that Amniotic membrane has proven its effect, as it initiates faster wound healing of the extraction socket. Conclusion: This article shall reveal the effectiveness of the Human amniotic membrane in rapid wound healing of the augmented extraction socket.

2019 ◽  
Vol 6 (3) ◽  
pp. 347-357 ◽  
Author(s):  
Md. Liakat Hossain ◽  
Md. Arifur Rahman ◽  
Ayesha Siddika ◽  
M. H. Adnan ◽  
Hafizur Rahman ◽  
...  

2020 ◽  
Vol 9 ◽  
pp. 1759
Author(s):  
Nader Tanideh ◽  
Farideh Keshavarzi ◽  
Aida Hemat Zadeh ◽  
Sajad Daneshi ◽  
Omid Koohi-Hosseinabadi ◽  
...  

ackground: This study aimed to compare sheep burnt wool and human amniotic membrane (AM) on second-degree burn wound healing in rats. Materials and Methods: Seventy-two adult male rats of Sprague Dawley underwent general anesthesia, and a deep second-degree burn was created on their skin by a hot iron plate. Afterward, human AM, silver sulfadiazine ointment (SSD), and sheep burned wool were used on wound area for burn treatment. On days 7, 14, and 21 of the experiment, the rats were sacrificed, and histopathological assessments were done. Results: Human AM, in comparison with other groups, significantly (P<0.05) showed better improvement in all pathologic variables. Burned wool showed significant improvement compared to the control group on day 7 in the angiogenesis, on day 14 in granulation tissue formation and epithelial formation, and on day 21 in new epithelial formation (P<0.05). Burned wool compared with SSD ointment in granulation tissue formation improved significantly (P<0.05) on days 7 and 14. Also, SSD ointment in comparison with the control group significantly improved (P<0.05) granulation tissue formation and macrophage on day 7. Conclusion: Human AM has a significant effect on the treatment of second-degree burn. Burned wool has a better effect on wound healing than SSD ointment and negative control group without treatment in terms of granulation tissue and epithelium formation. [GMJ.2020;9:e1759]


Author(s):  
Md Shaifur Rahman ◽  
Rashedul Islam ◽  
Md Masud Rana ◽  
Lucas-Sebastian Spitzhorn ◽  
Mohammad Shahedur Rahman ◽  
...  

2020 ◽  
Vol 15 ◽  
Author(s):  
Ayesha Siddika ◽  
Md. Arifuzzaman ◽  
Liakat Hossain ◽  
Md. Hasib Adnan ◽  
Farzana Diba ◽  
...  

: Burn wound associated injury management is one of the major unresolved clinical concerns. Most of the drugs and dressing materials found in the market cause dose escalation and even exert side effects. Besides, a severe burn injury is susceptible to microbial infection that leads to prolonged hospital stay which ultimately causes a financial crisis to the victims. To get rid of this problem, researchers are being interested in developing such materials that are cost-effective, easily available and accelerate faster healing. Human amniotic membrane (AM) and various herbal extracts like curcumin are a potential source of burn wound healing. AM has various healing properties and is being used as a best burn wound dressing material for centuries. Similarly, curcumin has been proven as faster dressing material for the treatment of burn injury. Since both AM and curcumin are a potential source of burn and wound healing, if a gel/agent could be formulated by mixing these two things, this combination may be a potential therapeutic strategy to treat burn wound healing.


2020 ◽  
Vol 27 (06) ◽  
pp. 1249-1254
Author(s):  
Ibrahim Yamin ◽  
Ayesha ◽  
Ramla ◽  
Muhammad Ajmal

Objectives: The use of human amniotic membrane is essential new concept in wound healing which functions as a biodegradable scaffold on wound surface, as it is a rich hub of stem cells which play an important role in wound healing. Study Design: Randomized Control Trial. Setting: Department of Surgery THQ Hospital Gojra. Period: 1st January 2019 to 30 September 2019. Material & Methods: Experimental study using clinical trial. A case series of 50 patient cases were picked from surgical OPD. Who fall in criteria of chronic non-healing wound with at least three months duration comprising of diabetic, venous ulcers and traumatic non healing wound and neuropathic ulcers. All located on lower limbs. Results: All 50 patient were treated with standard protocol by applying freshly prepared amniotic membrane out of which 4 chronic wounds more than 4 year duration were not healed and 2 cases escaped from the study. HAM dressing was changed after every 7 days and its effect were studied by seeing measuring the reduction in wound size and improvement in pain, swelling and mental stress. Success rate was found about 90% with complete healing. Conclusion: There is a dire need in developing countries to promote the use of HAM, in chronic non healing wounds which is a biological membrane, readily available (free if fresh) with simple sterilization techniques, easy storage and easy application with ultimate goal in achieving speedy cost effective wound healing.


2021 ◽  
Vol 14 (5) ◽  
Author(s):  
Ramin Hamidi ◽  
Ebrahim Hazrati ◽  
Davood Abbasi Azar ◽  
Farzad Allameh ◽  
Babak Javanmard ◽  
...  

Background: Wound healing is a complex process and in some patients, it is a long process. Due to the presence of various underlying diseases in patients with cancer, this process is delayed, and as a result, the rate of complications increases. Therefore, some materials are needed to accelerate wound healing. Nowadays efficacy of dry human amniotic membrane in burn wounds and chronic wounds is proven; however, no studies have been performed on the effect of this tissue in the treatment of surgical wounds. Objectives: This study aimed at evaluating the efficacy of dry human amniotic membrane in the secondary repair of urological cancer surgery wounds. Methods: In this randomized clinical trial from January 2018 to June 2020, 40 patients who underwent urological cancer surgery and secondary intention wound healing were selected and randomly divided into 2 groups of 20 patients. In the case group, the dry human amniotic membrane was used for dressing wounds, and in the control group, normal dressing without an amniotic membrane was performed. Complications such as infection, sepsis, and reoperation, as well as the duration of wound healing and hospitalization of patients at intervals of 1 week, 1, and 3 months, were compared between the 2 groups. Results: The 2 groups matched in terms of gender, age, and wound location. The mean duration of hospitalization and wound healing was significantly lower in the case group (P < 0.05). The rate of complications was higher in the control group but was not significant. Conclusions: Dry human amniotic membranes due to the accelerated wound healing process and fewer complications could be a good choice for secondary healing of wounds after urological cancer surgery.


2005 ◽  
Vol 46 (2) ◽  
pp. 479 ◽  
Author(s):  
Lung-Kun Yeh ◽  
Wei-Li Chen ◽  
Wei Li ◽  
Edgar M. Espana ◽  
Jie Ouyang ◽  
...  

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