scholarly journals Mystery of Mesenteric Lymph Adenitis

2021 ◽  
pp. 153-158
Author(s):  
R. Prathap ◽  
D. Ramachandra Reddy
Keyword(s):  
Bacterial Infections ◽  
Histoplasma Capsulatum ◽  
Fungal Infections ◽  
Ac Machines ◽  
Barr Virus ◽  
Mesenteric Lymph ◽  
Causative Factors ◽  
The Face ◽  
Epstein Barr ◽  
Aerosol Infection

The etiological factors are confusing for provisional diagnosis and the differential diagnosis of mesenteric lymph adenitis; it may be virus like Dengue, Herpes and Epstein - Barr virus. Bacterial infections like Tuberculosis of the intestine through contaminated unpasteurized cattle milk or Mycobacterium tuberculosis through infected swallowed sputum. T. Gondii, Yesinia enterocolitica, pseudo tuberculosis infection. Lupus vulgaris in the face at the mucocutaneous junctions is a reactivation of already existing tuberculosis facilitates clinical diagnosis. Fungal infections like mucor mycosis, aspergillus, Fusarium producing neutropenia, Histoplasma capsulatum, Cryptococcus aerosol infection from droppings of pigeons on the AC machines. Kikuchi-Fujimoto’s disease (KFD) .  Autoimmune causative factors. A study to reveal the mystery on patients with above symptoms and signs to rule out infections or a complication of follicular lymphoma.

scholarly journals Quantification of Torque Teno Virus and Epstein-Barr Virus Is of Limited Value for Predicting the Net State of Immunosuppression After Lung Transplantation

2018 ◽  
Vol 5 (4) ◽  
Author(s):  
Rickard Nordén ◽  
Jesper Magnusson ◽  
Anna Lundin ◽  
Ka-Wei Tang ◽  
Staffan Nilsson ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Immune Suppression ◽  
Bacterial Infections ◽  
Epstein Barr Virus ◽  
Respiratory Infections ◽  
Fungal Infections ◽  
Immunosuppressive Treatment ◽  
Torque Teno Virus ◽  
Barr Virus ◽  
Epstein Barr

Abstract Background Major hurdles for survival after lung transplantation are rejections and infectious complications. Adequate methods for monitoring immune suppression status are lacking. Here, we evaluated quantification of torque teno virus (TTV) and Epstein-Barr virus (EBV) as biomarkers for defining the net state of immunosuppression in lung-transplanted patients. Methods This prospective single-center study included 98 patients followed for 2 years after transplantation. Bacterial infections, fungal infections, viral respiratory infections (VRTI), cytomegalovirus (CMV) viremia, and acute rejections, as well as TTV and EBV levels, were monitored. Results The levels of torque teno virus DNA increased rapidly after transplantation, likely due to immunosuppressive treatment. A modest increase in levels of Epstein-Barr virus DNA was also observed after transplantation. There were no associations between either TTV or EBV and infectious events or acute rejection, respectively, during follow-up. When Tacrolimus was the main immunosuppressive treatment, TTV DNA levels were significantly elevated 6–24 months after transplantation as compared with Cyclosporine treatment. Conclusions Although replication of TTV, but not EBV, appears to reflect the functionality of the immune system, depending on the type of immunosuppressive treatment, quantification of TTV or EBV as biomarkers has limited potential for defining the net state of immune suppression.

scholarly journals Epstein-Barr Virus Versus Novel Coronavirus-Induced Hemophagocytic Lymphohistocytosis: The Uncharted Waters

2020 ◽  
Vol 8 ◽  
pp. 232470962095010 ◽  
Author(s):  
Rawan Amir ◽  
Asim Kichloo ◽  
Jagmeet Singh ◽  
Ravinder Bhanot ◽  
Michael Aljadah ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Epstein Barr Virus ◽  
Genetic Mutations ◽  
High Grade ◽  
The Novel ◽  
Barr Virus ◽  
First Case ◽  
Epstein Barr ◽  
Virus Versus ◽  
Novel Coronavirus

Hemophagocytic lymphohistocytosis (HLH) is a hyperinflammatory syndrome characterized by fever, hepatosplenomegaly, and pancytopenia. It may be associated with genetic mutations or viral/bacterial infections, most commonly Epstein-Barr virus (EBV) and cytomegalovirus. As for the novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), also known as COVID-19 (coronavirus disease-2019), the cytokine storm it triggers can theoretically lead to syndromes similar to HLH. In this article, we report a case of a 28-year-old female who presented with high-grade fevers, found to have both SARS-CoV-2 and EBV infections, and eventually began to show signs of early HLH. To our knowledge, this is the first case reported in literature that raises the possibility of SARS-CoV-2–related HLH development.

An Epstein-Barr virus-associated lymphoproliferative lesion of the skin presenting as recurrent necrotic papulovesicles of the face

1996 ◽  
Vol 134 (4) ◽  
pp. 791-796 ◽  
Author(s):  
K.H. CHO ◽  
C.W. KIM ◽  
D.Y. LEE ◽  
S.J. SOHN ◽  
D.W. KIM ◽  
...  
Keyword(s):  
Epstein Barr Virus ◽  
Barr Virus ◽  
The Face ◽  
Epstein Barr

Detection of lymphocytes productively infected with Epstein–Barr virus in non-neoplastic tonsils

Microbiology ◽  
2000 ◽  
Vol 81 (5) ◽  
pp. 1211-1216 ◽  
Author(s):  
Tetsuya Ikeda ◽  
Ryo Kobayashi ◽  
Manabu Horiuchi ◽  
Yoshifumi Nagata ◽  
Makoto Hasegawa ◽  
...  
Keyword(s):  
Epstein Barr Virus ◽  
Immune Surveillance ◽  
Lymphoid Tissues ◽  
Healthy Individuals ◽  
Barr Virus ◽  
Multiple Copies ◽  
The Face ◽  
Infected Cells ◽  
Epstein Barr

Epstein–Barr virus (EBV) persists for life in the infected host. Little is known about EBV reactivation and regulation of virus persistence in healthy individuals. We examined tonsils of chronic tonsillitis patients to detect EBV transcripts, EBV genomes and lytic proteins. LMP1 transcripts were observed in 11 of 15 specimens and BZLF1 transcripts were detected in six. Multiple copies of EBV genome equivalents per cell, and ZEBRA- and viral capsid antigen-positive cells were also detected in tonsillar lymphocytes. These results indicate that EBV productively infected cells may survive in the face of immune surveillance in the tonsils. Thus, EBV replication may occur in tonsillar lymphocytes, and tonsillar lymphoid tissues may play a role in the maintenance of EBV load in vivo.

An Epstein-Barr virus-associated lymphoproliferative lesion of the skin presenting as recurrent necrotic papulovesicles of the face

1996 ◽  
Vol 134 (4) ◽  
pp. 791-796 ◽  
Author(s):  
K.H. CHO ◽  
C.W. KIM ◽  
D.Y. LEE ◽  
S.J. SOHN ◽  
D.W. KIM ◽  
...  
Keyword(s):  
Epstein Barr Virus ◽  
Barr Virus ◽  
The Face ◽  
Epstein Barr

scholarly journals Treatment of Infectious Mononucleosis with High Dose Vitamin D3 in Three Cases

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Schwalfenberg GK ◽  
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Infectious Mononucleosis ◽  
Epstein Barr Virus ◽  
Fungal Infections ◽  
High Dose ◽  
Significant Morbidity ◽  
Barr Virus ◽  
Epstein Barr ◽  
High Dose Vitamin

Infectious mononucleosis often results in significant morbidity and disability lasting up to six months. It is known that vitamin D induces cathelicidin production that can rapidly responds to some viral, bacterial and fungal infections. The Epstein Barr virus is able to block the vitamin D receptor thus blocking the ability to fight this infection. This article presents three cases, which responded quickly to loading doses of vitamin D (150,000-200,000 IU) followed by a month of 10,000IU daily.

scholarly journals Methylation of the Epstein-Barr Virus Genome in Normal Lymphocytes

Blood ◽  
1997 ◽  
Vol 90 (11) ◽  
pp. 4480-4484 ◽  
Author(s):  
Keith D. Robertson ◽  
Richard F. Ambinder
Keyword(s):  
B Cells ◽  
Epstein Barr Virus ◽  
Defense Mechanism ◽  
Immune Surveillance ◽  
Virus Genome ◽  
Barr Virus ◽  
The Face ◽  
Ebv Dna ◽  
Epstein Barr

Abstract Epstein-Barr virus (EBV) latent infection in B cells persists over years or decades despite a sustained cytotoxic immune response to viral antigens. We present data that methylated EBV DNA can be detected in the normal lymphocytes of healthy volunteers. Whereas methylation of foreign DNA has been recognized as a potential cellular defense mechanism, methylation of EBV DNA may be an essential part of the virus life cycle in vivo, explaining the persistence of virus-infected B cells in the face of immune surveillance. Methylation of the C promoter helps to prevent expression of the immunodominant antigens expressed from this promoter. First recognized in tumors, methylation-associated evasion of immune surveillance is not an aberration restricted to tumor tissue but is detected in normal EBV-infected lymphocytes. Methylation of the viral genome in latency also provides an explanation for the CpG suppression associated with EBV but not other large DNA viruses.

Epstein-Barr Virus-Associated Lymphoproliferative Skin Lesion with Recurrent Necrotic Papulovesicles of the Face

1999 ◽  
Vol 26 (7) ◽  
pp. 448-451 ◽  
Author(s):  
Doo Yeoul Jung ◽  
Ji Won Kim ◽  
Sook Kyung Lee ◽  
Won Woo Lee
Keyword(s):  
Skin Lesion ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
The Face ◽  
Epstein Barr

Human X-linked variable immunodeficiency caused by a hypomorphic mutation in XIAP in association with a rare polymorphism in CD40LG

Blood ◽  
2011 ◽  
Vol 118 (2) ◽  
pp. 252-261 ◽  
Author(s):  
Stéphanie Rigaud ◽  
Eduardo Lopez-Granados ◽  
Sophie Sibéril ◽  
Geoffrey Gloire ◽  
Nathalie Lambert ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Clinical Manifestations ◽  
Large Family ◽  
Genetic Determinants ◽  
Hypomorphic Mutation ◽  
Barr Virus ◽  
Epstein Barr ◽  
Rare Polymorphism

Abstract The present study focuses on a large family with an X-linked immunodeficiency in which there are variable clinical and laboratory phenotypes, including recurrent viral and bacterial infections, hypogammaglobulinemia, Epstein-Barr virus–driven lymphoproliferation, splenomegaly, colitis, and liver disease. Molecular and genetic analyses revealed that affected males were carriers of a hypomorphic hemizygous mutation in XIAP (XIAPG466X) that cosegregated with a rare polymorphism in CD40LG (CD40 ligandG219R). These genes are involved in the X-linked lymphoproliferative syndrome 2 and the X-linked hyper-IgM syndrome, respectively. Single expression of XIAPG466X or CD40LG219R had no or minimal effect in vivo, although in vitro, they lead to altered functional activities of their gene products, which suggests that the combination of XIAP and CD40LG mutations contributed to the expression of clinical manifestations observed in affected individuals. Our report of a primary X-linked immunodeficiency of oligogenic origin emphasizes that primary immunodeficiencies are not caused by a single defective gene, which leads to restricted manifestations, but are likely to be the result of an interplay between several genetic determinants, which leads to more variable clinical phenotypes.

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