scholarly journals Low Plasma Iron Levels Associated to Drug Treatment in Polymedicated Patients: A Case-Control Study

2020 ◽  
pp. 23-28
Author(s):  
R. Lozano ◽  
A. Frutos ◽  
A. Apesteguía ◽  
A Martinez ◽  
M. E. Franco ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Case Control Study ◽  
Case Control ◽  
Duration Of Treatment ◽  
Retrospective Case ◽  
Major Health Problem ◽  
Major Health ◽  
Plasma Iron ◽  
Medicine Service ◽  
Control Study

Aim: To identify the drug class and/or duration of treatments causing hyposideremia. Study Design: Retrospective case-control study. Place and Duration of Study: Departments of Internal Medicine and Pharmacy, Aragón Health Services Services Hospital Real de Nuestra Señora de Gracia, between January 2019 and December 2019. Methodology: The records of prescripted medicines of all patients admitted to Internal Medicine  service, for various indications, along a 1-year period (2019), which were  ultimately analized according to association with hyposideremia. Results: It was identified several drugs associated with low plasma iron levels: acetylcysteine and apixaban, which would increase the risk of hyposideremia. On the contrary, we found that allopurinol, duloxetine and simvastatin would protect against the appearance of hyposideremia. Conclusion: Acetylcysteine and apixaban, alone or in combination with different pathologies, would be capable of inducing, and on dependence of the duration of treatment and/or of the concomitant pathology, hyposideremia, iron deficiency and, in certain cases, anemia constituting a major health problem.

scholarly journals Hyposideremia Associated to Drug Treatment in Polymedicated Patients: a Case-Control Study

2019 ◽  
Author(s):  
Roberto Lozano ◽  
Alberto Frutos ◽  
Alberto Apesteguia ◽  
Alejandro Martinez ◽  
Esther Franco ◽  
...  
Keyword(s):  
Serum Iron ◽  
Drug Class ◽  
Case Control Study ◽  
Case Control ◽  
Duration Of Treatment ◽  
Major Health Problem ◽  
Major Health ◽  
Medicine Service ◽  
Prescription Medicines ◽  
Control Study

A case-control pharmaco-epidemiological study, aimed to identify the drug class and/or duration of treatments causing hyposideremia, was carried out. For this, the prescription medicines of all patients addmited to a Internal Medicine service, for various indications, along a 1-year period (2019), were recorded and, ultimately, its association to hyposideremia analyzed. As a result, it was identified several drugs associated with alterations in serum iron levels: acetylcysteine, apixaban and edoxaban, which would increase the risk of hyposideremia. On the contrary, we found that allopurinol, duloxetine and simvastatin would protect against the appearance of hyposideremia. These drugs, alone or in combination with different pathologies, would be capable of inducing, and on dependence of the duration of treatment and/or of the concomitant pathology, hyposideremia, iron deficiency and, in certain cases, anemia constituting a major health problem.

scholarly journals HUBUNGAN ANTARA KEPRIBADIAN DENGAN KEJADIAN RELAPS PADA PASIEN KANKER PAYUDARA DI POLI ONKOLOGI RSUD DR. SOETOMO SURABAYA

2020 ◽  
Vol 5 (2) ◽  
pp. 45
Author(s):  
Danang Nur Adiwibawa
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Big Five ◽  
Case Control Study ◽  
Case Control ◽  
Personality Factors ◽  
Breast Cancer Patients ◽  
Major Health Problem ◽  
Major Health ◽  
Control Study

Background. Breast cancer is a major health problem that affects the lives of millions of women. Some patients have treatment but still found relapse.Suggest personality factors influence relapse breast cancer.But until now it is still controversy. Methods. Analytic research observational case control study to find relationship between personality with the incidence of relapse in breast cancer patients and comparing personality relapse and non relapse. Research in Poli Onkologi RSUD Dr.Soetomo with 56 patients,28 patients relapse and 28 non relapse.Use Instrument OCEAN-Big Five Inventory 44 Quessioner and Demogarfi Quessioner. Result. There is no relationship between personality with incidence of relapse (p>0,05). neuroticism personality (29%) in relapse, openness personality (32%) and extraversion personality (36%) in non relapse. Conclusion. The incidence of relapse breast cancer is not simply due to personality but maybe other factors.

Assessment of Craniofacial Morphology in Mouth Breathing Children. A retrospective case-control study

2019 ◽  
Vol 70 (10) ◽  
pp. 3649-3653
Author(s):  
David Angelescu ◽  
Teodora Angelescu ◽  
Meda Romana Simu ◽  
Alexandrina Muntean ◽  
Anca Stefania Mesaros ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Craniofacial Morphology ◽  
Respiratory Pattern ◽  
Control Group ◽  
Upper Lip ◽  
Retrospective Case ◽  
Oral Breathing ◽  
Facial Height ◽  
Control Study

The aim of this retrospective case-control study is to determine a possible correlation between breathing mode and craniofacial morphology. The study was carried out in the Department of Pedodontics,Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. The sample comprised 80 patients, age between 6 and 13 years, which were divided in two groups based on respiratory pattern: control group composed of 38 nasal breathing children and case group composed of 42 oral breathing children. Three quantitative craniofacial parameters were measured from the frontal and lateral photos: facial index, lower facial height ratio and upper lip ratio. The statistical analysis showed a significant higher facial index (p=0.006*) and an increase lower facial height (p=0.033*) for the oral breathers group. No differences in facial morphology were found between genders and age groups, when comparing the data between the same type of respiratory pattern children. Spearman�s rho Correlation show a significant positive correlation (p=0.002*) between facial index and lower facial height and a significant negative correlation between facial index and upper lip (p=0,005*). Long faces children are more likely to develop oral breathing in certain conditions, which subsequently have a negative effect on increasing the lower facial height by altering the postural behavior of mandible and tongue.

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