scholarly journals Evaluation of Antifungal and Antioxidant Effects of Qutran (Wood Tar) from Olea europaea Subsp. Cuspidate

Author(s):  
Nehad M. Gumgumjee

Qutran oil (Olea europaea) extracted as medicinal plants extracted has a great activity against four fungistrains. Aspergillus (flavus, fumigatus, niger) and Candida albicans throughout using agar well diffusion in our investgation. Results showed that, tar oilhas antifungal effects against studied strains. Inhibition growth rate was from 16.33 to 46.00 mm. and also has positive activities against investagated organisms more than traditional antibiotics either amphoteracin B or Nystatin. A. fumigatus was mainly susceptible fungi followed by A. niger while A.  flavus has the  most resistant fungi with inhibition zone (16.33 mm). Wood tar oil, Olea europaea, given a high DPPH radical scavenging activity 79.10% compared to ascorbic acid.

2018 ◽  
Vol 44 (4) ◽  
pp. 515-520
Author(s):  
M Kazemi

Carum copticum L. comprises several relevant species for food, cosmetic, perfumery and pharmaceutical industries. GC/MS analysis of the enential oil of C. copticum revealed γ- terpinene as a major component of C. copticum, with its contribution of 33.85%. Essential oils (EOs) exhibited a significant antimicrobial activity against all tested microbial strains. In addition, the C. copticum oil demonstrated the highest DPPH radical scavenging activity. These results clearly show the antimicrobial and antioxidant effects of the plant essential oil.


2020 ◽  
Vol 16 (2) ◽  
pp. 174-180 ◽  
Author(s):  
Nacera Baali ◽  
Baali Samiya ◽  
Bentamen Ali ◽  
Benayache Samir ◽  
Benayache Fadila ◽  
...  

Background: The ability of Centaurea maroccana (C. maroccana) and Centaurea acaulis (C. acaulis) to protect the kidney against CCl4-induced renal toxicity in male rats was investigated. Moreover, the total polyphenols and flavonoids amount and DPPH radical scavenging activity were estimated. Materials and Methods: Rats were pre-treated orally with C. maroccana and C. acaulis (200 mg/kg, daily for 2 weeks) along with CCl4 (1.5 ml/kg, three times a week for 2 weeks). At the end of the treatment procedure, all rats were sacrificed and renal protective effect of C. maroccana and C. acaulis was evaluated. Results: Administration of CCl4 alone significantly elevated kidney malondialdehyde, as well as serum creatinine, urea and uric acid. While kidney level of glutathione and catalase were reduced. These were accompanied by glomerular and tubular degenerations and necrosis. Pre-treatment with C. maroccana and C. acaulis ameliorated the above mentioned biochemical parameters and histological changes associated with nephrotoxicity induced by CCl4. Moreover, both studied extracts showed a noticeable total polyphenols and flavonoids amount and antioxidant activity in DPPH assays. Conclusion: From the results, it is suggested that C. maroccana and C. acaulis extract has the ability to protect kidney against oxidative damages, possibly through the antioxidant effects of their bioactive compounds.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Cassia Sacchet ◽  
Ricieri Mocelin ◽  
Adrieli Sachett ◽  
Fernanda Bevilaqua ◽  
Rafael Chitolina ◽  
...  

The jaboticaba tree,Plinia trunciflora(O. Berg) Kausel, is popularly named “jabuticabeira” in Brazil and is used in folk medicine to treat diabetes and chronic inflammation of the tonsils, but studies evaluating the central effects of this species are limited. This study evaluated the antidepressant-like and antioxidant effects ofP. trunciflora(PT) aqueous extract, in which five different anthocyanins were identified. PT showed significant ferric-reduction power and DPPH radical scavenging activityin vitroand reduced lipid peroxidation bothin vitroandex vivo. At the behavioural level, PT (400 and 800 mg/kg, i.p.) dose-dependently reduced immobility time in the tail suspension test in Swiss male mice. The identification of bioactive compounds accompanied by thein vitroandex vivoantioxidant activity of PT suggests that these activities might be related to the antidepressant-like activity ofP. trunciflora.


2021 ◽  
Vol 11 (4) ◽  
pp. 8065-8070
Author(s):  
Himabindu K ◽  
Vijayalakshmi A

Ficus dalhousie and Melissa parviflora Benth both plants have been used as Tranquiliser, Relaxants, Nervine tonic and Calming aids throughout the world. The present study was aimed to identify the antioxidant potential of the Ethyl acetate and Hydro alcoholic extract of these plants by in vitro methods. Anti-Alzheimer activity of the plant extract were screened by Acetylcholinesterase (AChE) inhibition and antioxidant by DPPH and Hydrogen oxide. The results of the assays were calculated by the percentage inhibition of these free radicals. In Acetylcholinesterase (AChE) assay inhibitory potentials of Ficus dalhousie exhibited 73.34 ± 1.12%, whereas in Melissa  arviflora it was 86.88± 2.12%. In DPPH radical scavenging assay the percentage inhibition was 77.87 ± 2.02% in Ficus dalhousie and 76.92± 1.32% in Melissa  arviflora. Hydrogen peroxide scavenging assay the percentage inhibition was 86.56 ± 1.05% in Ficus dalhousie and 80.75± 1.92% was in Melissa arviflora. In all the research assays, the extract showed a concentration dependent increase in free radical scavenging activity. The results revealed that the antioxidant effects of the plant extract might be due to the presence of phenol and flavonoid compounds. 


2019 ◽  
Vol 31 (7) ◽  
pp. 1558-1564
Author(s):  
Aisha M. Turkustani ◽  
Nehad M. Gumgumji ◽  
Abdulrahman S. Al Hajar

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Anindya Sundar Ray ◽  
Suman Kalyan Mandal ◽  
Chowdhury Habibur Rahaman

Solanum glaucophyllum Desf. (Solanaceae) is traditionally used for curing several health conditions in both human and domesticated animals. There is no data available regarding pharmacognostic standardization and pharmacological activity of this less known medicinal plant. Therefore, the aim of the present work is to prepare pharmacognostic fingerprints of crude drugs obtained from the leaf and stem parts of S. glaucophyllum. Apart from this detailed phytochemical analysis, antioxidant and antimicrobial studies have also been carried out. Pharmacognostic study revealed that the leaves are amphistomatic and stomata are strictly of anisocytic type. Values of stomatal index, palisade ratio, ash content of the investigated parts are found distinct and can be used as pharmacognostic standards for evaluation of crude drugs of this medicinal plant. Phytochemical studies of the leaf and stem parts indicated that phenolics, flavonoids, tannins and alkaloids are present in quite impressible amount. Curcumin content in stem was found very high through HPLC analysis. In DPPH radical scavenging assay, the stem part showed significant antioxidant potential. Ethanol extract of stem produced maximum inhibition zone (11mm) against Pseudomonas aeruginosa at the concentration of 50 mg/ml among five test microorganisms. Some pharmacognostic features recorded in this study as diagnostic ones will help in proper identification of this ethnomedicinal plant in its fresh as well as dried form. On the other hand preliminary phytochemical, antioxidant and antimicrobial studies highlight the S. glaucophyllum as a promising candidate for bioprospecting.


2020 ◽  
Vol 2020 ◽  
pp. 1-16
Author(s):  
Nur Sumirah Mohd Dom ◽  
Nurshieren Yahaya ◽  
Zainah Adam ◽  
Nik Mohd Afizan Nik Abd. Rahman ◽  
Muhajir Hamid

The present study aimed to evaluate the potential of standardized methanolic extracts from seven Ficus deltoidea varieties in inhibiting the formation of AGEs, protein oxidation, and their antioxidant effects. The antiglycation activity was analyzed based on the inhibition of AGEs, fructosamine, and thiol groups level followed by the inhibition of protein carbonyl formation. The antioxidant activity (DPPH radical scavenging activity and reducing power assay) and total phenolic contents were evaluated. After 28 days of induction, all varieties of Ficus deltoidea extracts significantly restrained the formation of fluorescence AGEs by 4.55–5.14 fold. The extracts also reduced the fructosamine levels by 47.0–86.5%, increased the thiol group levels by 64.3–83.7%, and inhibited the formation of protein carbonyl by 1.36–1.76 fold. DPPH radical scavenging activity showed an IC50 value of 66.81–288.04 μg/ml and reducing power activity depicted at 0.02–0.24 μg/ml. The extent of phenolic compounds present in the extracts ranged from 70.90 to 299.78 mg·GAE/g. Apart from that, correlation studies between the activities were observed. This study revealed that seven varieties of Ficus deltoidea have the potential to inhibit AGEs formation and possess antioxidant activity that might be attributed to the presence of phenolic compounds.


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