scholarly journals Nevirapine Induced Exfoliative Dermatitis: A Case Report

2014 ◽  
Vol 13 (4) ◽  
pp. 01-03
Author(s):  
Dr.Ramya. Rachamanti ◽  
◽  
Dr.Mattam Bheemesh Naidu ◽  
Dr.Keelu Raj kumar
1970 ◽  
Vol 6 (2) ◽  
pp. 64-66 ◽  
Author(s):  
Rajat Roy ◽  
Anil Bhattarai ◽  
Prativa Shrestha ◽  
Upama Paudel ◽  
Sudip Parajuli

One 11 year old female attended dermatology OPD of College of Medical Sciences, Bharatpur. She was undergoing treatment with Dapsone for one month for Borderline lepromatous leprosy. There was history of dry scales for 3 weeks over trunk, buttock, face, back and lower extremities suggestive of Exfoliative Dermatitis. The patient was treated with Prednisolone with supportive therapy for one month. Recovery is good. Key words: Dermatology; lepromatous leprosy; exfoliative dermatitis. DOI: 10.3126/jcmsn.v6i2.3621 Journal of college of Medical Sciences-Nepal, 2010, Vol.6, No-2, 64-66


Author(s):  
Chirag J. Vamja ◽  
Vasudha A. Belgaumkar ◽  
Nitika S. Deshmukh ◽  
Sunil N. Tolat

<p>Skin can provide a vital clue to diagnosis of internal disease. Exfoliative dermatitis (erythroderma) is an uncommon potentially serious inflammatory skin disorder characterized by an intense, widespread erythema and variable scaling. It results from aggravation of pre-existing skin disease, or may be caused by drugs or neoplasms. Although various paraneoplastic dermatoses may occur in association with carcinoma lung, erythroderma as the sole presenting feature is infrequently reported in literature. Herein we describe an elderly male in whom recalcitrant erythroderma led to the diagnosis of squamous cell carcinoma lung with fatal outcome.</p>


2013 ◽  
Vol 80 (07) ◽  
pp. 63-66 ◽  
Author(s):  
Yan Keqiang ◽  
Liu Cheng ◽  
Xu Zhonghua ◽  
Liu Zhaoxu ◽  
Wang Kun ◽  
...  

2015 ◽  
Vol 11 (2) ◽  
pp. 543-546 ◽  
Author(s):  
ZHIHONG QIU ◽  
HONGTAO LIU ◽  
LIEN HE ◽  
YINLING MA ◽  
HAOJING SONG ◽  
...  

1957 ◽  
Vol 17 (9) ◽  
pp. 1094-1098 ◽  
Author(s):  
A. HARELL-STEINBERG ◽  
L. ZIPRKOWSKI ◽  
S. HAIM ◽  
J. GAFNI ◽  
M. LEVIN

Author(s):  
Mila Nu Nu Htay ◽  
Wai Wai Myint ◽  
Htay Lwin ◽  
Win Htay

Erythroderma is a scaly, erythematous dermatitis of the skin, which occurs in drug allergy, malignancy and underlying skin disorders. The diagnosis is challenging because the extent of skin involvement does not always correlate with the extent of internal organ involvement. Therefore, early recognition of symptoms is vital to minimize morbidity and mortality. Case report: A 52 years old man had asymptomatic hyperuricemia and prescribed allopurinol 300mg, daily. One month later, the rashes started to appear on his trunk and then progressed to the face and upper limbs. Then it continued to spread to the lower extremities. Management involves prompt cessation of the culprit drug, administration of corticosteroids and supportive treatment. It is Concluded that Allopurinol is commonly used in clinical practice for the treatment of symptomatic hyperuricemia and gout. It has been associated with erythroderma especially when used indiscriminately.


2017 ◽  
Vol 7 (2) ◽  
pp. 168-171
Author(s):  
Farhana Afroz ◽  
Md Delwar Hossain ◽  
Jamal Uddin Ahmed ◽  
Wasim Md Mohosinul Haque

Rifampicin is one of the most effective antitubercular agents. Among its rare adverse effects, acute interstitial nephritis is noteworthy. Furthermore, exfoliative dermatitis caused by rifampicin is quite uncommon. Simultaneous occurrence of the both complications in the same patient has not been reported so far. Here we describe a case history of a 76-year-old male who developed rifampicin induced acute interstitial nephritis and exfoliative dermatitis at the same time.Birdem Med J 2017; 7(2): 168-171


2019 ◽  
Vol 14 (1) ◽  
pp. 37-39 ◽  
Author(s):  
Aashiq Ahamed Shukkoor ◽  
Saravanan Thangavelu ◽  
Nimmy Elizabeth George ◽  
Shanmuga Priya

Background: Dapsone is a sulfone derived drug used in the treatment of leprosy and several chronic inflammatory dermatological diseases. Dapsone Hypersensitivity Syndrome (DHS) is characterized by fever, hepatitis, generalized exfoliative dermatitis and lymphadenopathy. It is rare and potentially fatal. Case Report: We present a case report of a 52 years old female with a recent history of antecedent dapsone exposure of 100 mg daily for 2 weeks. She developed fever 10 days after exposure to dapsone therapy and was treated in various primary and tertiary centers for features of sepsis. When she presented to us, clinical features of multi-organ dysfunction and intractable sepsis was evident. She was successfully managed with intravenous corticosteroids and other supportive therapy. This case of DHS is unique due to pulmonary, hepatic and colonic involvement in addition to secondary bacterial and fungal infection, which is associated with an increased risk of mortality. Conclusion: As dapsone is mainstay in the treatment several infections and inflammatory conditions, further research is needed to characterize markers to diagnose DHS and to develop screening policies prior to initiation of dapsone therapy.


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