scholarly journals Dapsone induced exfoliative dermatitis: A case report

1970 ◽  
Vol 6 (2) ◽  
pp. 64-66 ◽  
Author(s):  
Rajat Roy ◽  
Anil Bhattarai ◽  
Prativa Shrestha ◽  
Upama Paudel ◽  
Sudip Parajuli
Keyword(s):  
Case Report ◽  
Key Words ◽  
Supportive Therapy ◽  
Lower Extremities ◽  
Lepromatous Leprosy ◽  
Medical Sciences ◽  
Exfoliative Dermatitis ◽  
History Of

One 11 year old female attended dermatology OPD of College of Medical Sciences, Bharatpur. She was undergoing treatment with Dapsone for one month for Borderline lepromatous leprosy. There was history of dry scales for 3 weeks over trunk, buttock, face, back and lower extremities suggestive of Exfoliative Dermatitis. The patient was treated with Prednisolone with supportive therapy for one month. Recovery is good. Key words: Dermatology; lepromatous leprosy; exfoliative dermatitis. DOI: 10.3126/jcmsn.v6i2.3621 Journal of college of Medical Sciences-Nepal, 2010, Vol.6, No-2, 64-66

Dapsone Hypersensitivity Syndrome (DHS): A Detrimental Effect of Dapsone? A Case Report

2019 ◽  
Vol 14 (1) ◽  
pp. 37-39 ◽  
Author(s):  
Aashiq Ahamed Shukkoor ◽  
Saravanan Thangavelu ◽  
Nimmy Elizabeth George ◽  
Shanmuga Priya
Keyword(s):  
Case Report ◽  
Detrimental Effect ◽  
Supportive Therapy ◽  
Hypersensitivity Syndrome ◽  
Exfoliative Dermatitis ◽  
Colonic Involvement ◽  
Inflammatory Conditions ◽  
Risk Of Mortality ◽  
Increased Risk ◽  
History Of

Background: Dapsone is a sulfone derived drug used in the treatment of leprosy and several chronic inflammatory dermatological diseases. Dapsone Hypersensitivity Syndrome (DHS) is characterized by fever, hepatitis, generalized exfoliative dermatitis and lymphadenopathy. It is rare and potentially fatal. Case Report: We present a case report of a 52 years old female with a recent history of antecedent dapsone exposure of 100 mg daily for 2 weeks. She developed fever 10 days after exposure to dapsone therapy and was treated in various primary and tertiary centers for features of sepsis. When she presented to us, clinical features of multi-organ dysfunction and intractable sepsis was evident. She was successfully managed with intravenous corticosteroids and other supportive therapy. This case of DHS is unique due to pulmonary, hepatic and colonic involvement in addition to secondary bacterial and fungal infection, which is associated with an increased risk of mortality. Conclusion: As dapsone is mainstay in the treatment several infections and inflammatory conditions, further research is needed to characterize markers to diagnose DHS and to develop screening policies prior to initiation of dapsone therapy.

Spontaneous intramural duodenal hematoma in a young woman

2021 ◽  
Vol 75 (6) ◽  
pp. 535-539
Author(s):  
Petra Vrbová ◽  
Tomáš Koller
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Case Report ◽  
Key Words ◽  
Clinical Symptoms ◽  
Supportive Therapy ◽  
Gastrointestinal Obstruction ◽  
History Of ◽  
Duodenal Hematoma ◽  
Upper Abdominal

Summary: Non-traumatic spontaneous intramural duodenal hematoma is a rare cause of proximal gastrointestinal obstruction which may present with hemorrhage, jaundice and pancreatitis. In this case report we present a case of spontaneous duodenal hematoma in a 28-year-old female with a history of acute pancreatitis, admitted to hospital for convulsive upper abdominal pain with vomiting as suspected pancreatitis. An MRI examination of the abdomen confi rmed intraluminal bleeding into the duodenum. Following supportive therapy the clinical symptoms spontaneously subsided and laboratory parameters improved. Due to early dia gnosis and therapy the patient had a good outcome, without requiring surgery. Repeated imaging showed hematoma resorption. Key words: abdominal pain – vomitus – duodenal hematoma – hemorrhage

scholarly journals PROXIMAL BRACHIAL MONOMELIC AMYOTROPHY OR HIRAYAMA DISEASE: NO LONGER AN ALIAS? (case report)

2019 ◽  
Vol 5 (1) ◽  
pp. 5-9
Author(s):  
Akshay Rao
Keyword(s):  
Case Report ◽  
Cervical Spine ◽  
Upper Limb ◽  
Clinical Status ◽  
Supportive Therapy ◽  
Neutral Position ◽  
Mri Findings ◽  
Limb Weakness ◽  
Hirayama Disease ◽  
History Of

Background. Brachial Monomelic Amyotrophy (BMMA) has been called as Hirayama disease (HD) when it is characterized by unilateral distal upper limb weakness and atrophy that shows progression for a limited period and is associated with typical features on MRI of cervical spine in flexion. Objective was to explore the differences when BMMA affects the proximal upper limb muscles with the help of case report. Methods. A case report of BMMA in an adult Indian male is represented. Results. A 30-year-old man presented to us with a history of weakness in the proximal aspect of his left upper limb that began four years ago. The weakness was progressive up until 6 months prior to his presentation since when the weakness had neither worsened nor improved. Cervical spine contrast enhanced MRI revealed mild loss of cervical lordosis, but no features of HD like localized cord atrophy, loss of attachment of dura from subjacent lamina on neutral position axial T2WI MRI, nor any presence of posterior epidural crescentic enhancing mass on flexion contrast sagittal T1WI MRI. The patient was managed with supportive therapy and has been under regular follow up ever since. His clinical status has been stable. Conclusions. We support the suggestion to consider proximal Brachial Monomelic Amyotrophy to be a separate entity and to be distinguished from Hirayama disease that should be reserved for patients with distal upper limb involvement with cervical MRI findings on flexion studies.

scholarly journals Ureterocele – A case report

1970 ◽  
Vol 6 (2) ◽  
pp. 38-41 ◽  
Author(s):  
PK Chhetri ◽  
SK Malla
Keyword(s):  
Case Report ◽  
Urinary Tract ◽  
Key Words ◽  
Young Patient ◽  
Urinary Tract Obstruction ◽  
In Utero ◽  
Single System ◽  
Medical Sciences ◽  
Collection System ◽  
Ureteral Duplication

Congenital ureterocele is an uncommon cause of urinary tract obstruction in the young patient. Though they may be diagnosed in utero, some however present in the first few decades of life. Most are associated with a duplex collection system with complete ureteral duplication. Here we report a case of single system ureterocele associated with only a single ureter. Key words: ureterocele; urinary tract obstruction. DOI: 10.3126/jcmsn.v6i2.3615 Journal of college of Medical Sciences-Nepal, 2010, Vol.6, No-2, 38-41

scholarly journals Group a streptococcal cellulitis in the early puerperium

2011 ◽  
Vol 68 (7) ◽  
pp. 607-610
Author(s):  
Branka Nikolic ◽  
Ana Mitrovic ◽  
Svetlana Dragojevic-Dikic ◽  
Snezana Rakic ◽  
Zlatica Cakic ◽  
...  
Keyword(s):  
Case Report ◽  
Toxic Shock Syndrome ◽  
Early Recognition ◽  
Healthy Woman ◽  
Supportive Therapy ◽  
Streptococcal Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Short Period ◽  
History Of ◽  
Group A

Introduction. Infectious diseases caused by Streptococcus pyogenes, a member of the group A Streptococci (GAS) are among the most common life threatening ones. Patients with GAS infections have a poor survival rate. Cellulitis is a severe invasive GAS infection and the most common clinical presentation of the disease associated with more deaths than it can be seen in other GAS infections. According to the literature data, most cases of GAS toxic shock syndrome are developed in the puerperium. However, there are two main problems with GAS infection in early puerperium and this case report is aimed at reminding on them. The first problem is an absence of awareness that it can be postpartal invasive GAS infection before the microbiology laboratory confirms it, and the second one is that we have little knowledge about GAS infection, in general. Case report. A 32- year-old healthy woman, gravida 1, para 1, was hospitalized three days after vaginal delivery with a 38-hour history of fever, pain in the left leg (under the knee), and head injury after short period of conscious lost. Clinical picture of GAS infection was cellulites. Group A Streptoccocus pyogenes was isolated in vaginal culture. Rapid antibiotic and supportive treatment stopped development of streptococcal toxic shock syndrome (STSS) and potential multiorganic failure. Signs and symptoms of the infection lasted 25 days, and complete recovery of the patient almost 50 days. Conclusion. In all women in childbed with a history of fever early after delivery, vaginal and cervical culture specimens should be taken as soon as possible. Early recognition of GAS infection in early puerperium and prompt initiation of antimicrobial drug and supportive therapy can prevent development of STSS and lethal outcome.

scholarly journals N-ACETYLCYSTEINE, A BOON FOR YELLOW PHOSPHORUS-INDUCED ACUTE LIVER FAILURE? A CASE REPORT

2019 ◽  
pp. 1-3 ◽  
Author(s):  
AASHIQ AHAMED SHUKKOOR ◽  
NIMMY ELIZABETH GEORGE ◽  
SARAVANAN THANGAVELU
Keyword(s):  
Case Report ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Lethal Dose ◽  
Supportive Therapy ◽  
Phosphorus Poisoning ◽  
Yellow Phosphorus ◽  
Phosphorus Containing ◽  
History Of ◽  
Anti Oxidant

Rat killer, in the form of a paste, is a commonly used rodenticide in India. It contains 3% yellow phosphorus, which is a local and a systemic toxin that damages all tissues it contacts. The lethal dose of yellow phosphorus is about 1 mg/kg of body weight. We present a case report of a 30-year-old female patient with an alleged history of intake of 30 g rat killer paste mixed with one glass juice with suicidal intent. She presented with clinical features of acute liver failure (ALF) and was treated with N-acetylcysteine (NAC) infusion with other supportive therapy and recovered completely within 13 days. Poisoning with yellow phosphorus needs to be studied in the aspect of treatment, due to the lack of any specific antidote. The patient factors that help in the recovery also need to be investigated. Although highly lethal, the recovery of ALF due to yellow phosphorus-containing rodenticide is possible. Early intravenous administration of NAC, which acts as glutathione substitute, anti-inflammatory agent, and anti-oxidant could contribute to complete resolution of ALF in yellow phosphorus poisoning.

scholarly journals Successful Management of Spondylodescitis in a Three Years Old Girl: A Case Report

2020 ◽  
pp. 5-7
Author(s):  
Khadija Saleh ◽  
AL Zahraa Hamed ◽  
Ali AL Sharqi ◽  
Hilal Al Hashami
Keyword(s):  
Emergency Department ◽  
Back Pain ◽  
Case Report ◽  
Early Intervention ◽  
Rare Diseases ◽  
Lower Extremities ◽  
Complete Recovery ◽  
Successful Management ◽  
Lumbar Back Pain ◽  
History Of

Spondylodescitisis considered one of the rare diseases that cause back pain. The disease pathology is not yet been clearly known, however, in most patients the disease thought to be spreading hematogenously from a previously existing site of infection. We report two years and 11 months old child, previously healthy girl, presented to the emergency department with two weeks’ history of weakness of the lower extremities and lumbar back pain with slightly arched back. She had a complete recovery with early intervention and complete course of antibiotics.

scholarly journals Norwegian scabies- A case report

1970 ◽  
Vol 6 (2) ◽  
pp. 47-49
Author(s):  
Sima Kumari Kedia ◽  
Mahesh Mathur
Keyword(s):  
Case Report ◽  
Key Words ◽  
Health Workers ◽  
Point Of View ◽  
Social Health ◽  
Medical Sciences ◽  
Rare Form

Norwegian scabies is a rare form of a common ectoparasitic infestation of skin. Case report is of importance for the general practicerners point of view and for the information of preventive and social health workers. Key words: Norwegian scabies; ectoparisite. DOI: 10.3126/jcmsn.v6i2.3617 Journal of college of Medical Sciences-Nepal, 2010, Vol.6, No-2, 47-49

scholarly journals Carcinoma of Left Breast with Secondary Metastatic Cord Compression- A Case Report

1970 ◽  
Vol 18 (1) ◽  
pp. 51-52
Author(s):  
Md L Rahman ◽  
ASM Shawkat Ali ◽  
MI Alam
Keyword(s):  
Spinal Cord ◽  
Case Report ◽  
Lower Extremities ◽  
Large Mass ◽  
Cord Compression ◽  
Left Breast ◽  
Thoracic Level ◽  
Simple Mastectomy ◽  
History Of ◽  
One Year

A 45-year-old female presented with weakness of lower extremities with history of simple mastectomy one year back. On myelographic examination showed complete block at mid thoracic level which is extra-dural in nature. On operation extra-dural large mass compressing the spinal cord at T5 level was detected.   doi: 10.3329/taj.v18i1.3306 TAJ 2005; 18(1): 51-52

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