Drug Utilization Pattern of Psychotropic Drugs Prescribed in the Psychiatric Department of a Tertiary Care Government Hospital, Rajasthan

ABSTRACTObjective: The growing concern over the burden of psychiatric illnesses in health statistics elicit the importance of rational prescribing of psychotropicdrugs. Due to the minimal number of studies conducted in this area, the present study was carried out to assess the morbidity pattern and prescribingtrend of drugs used in psychiatric outpatients.Methods: This prospective observational study was conducted for a period of 6-month in a psychiatric outpatient department. The medical recordsof 202 patients were reviewed for analyzing the prescription pattern using the World Health Organization drug indicators, wherein patients werecategorized according to the International Classification of Diseases-10 criteria.Results: In the present study, 129 (63.9%) of the 202 patients were males. The majority of the patients (36.63%) were in the age group of 25-35 years.Substance-related disorders (28.71%) were the most common psychiatric disorders followed by schizophrenia and other psychotic disorders(22.77%). Anxiolytics and hypnotics (31.99%) were the most commonly prescribed psychotropic drug class followed by antipsychotics (20.2%) andantidepressants (18.18%) with clonazepam (47.89%), risperidone (42.5%), and escitalopram (57.4%) being the most common drugs, respectively.Polypharmacy was found in 93.56% of the prescriptions with an average of 3.396 drugs/prescription. Generic drug usage (39.94%) was found to below when compared to the brand drug usage (60.05%).Conclusion: Benzodiazepines were the most commonly used psychotropic drugs. Polypharmacy, although practiced as a treatment strategy tomanage psychiatric illnesses, predisposes patients to adverse events and adherence issues.Keywords: Drug utilization pattern, Psychotropic drugs, Polypharmacy, Psychiatric outpatients.

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DRUG UTILIZATION PATTERN OF ANTIHYPERTENSIVES IN GERIATRIC AND NON GERIATRIC POPULATION IN A TERTIARY CARE GOVERNMENT HOSPITAL SRIKAKULUM, A . P .

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2015/302 ◽

2015 ◽

Vol 04 (13) ◽

pp. 2101-2106 ◽

Cited By ~ 1

Author(s):

Sujatha Patta

Keyword(s):

Drug Utilization ◽

Tertiary Care ◽

Government Hospital ◽

Utilization Pattern ◽

Geriatric Population

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Study of drug utilization pattern and adverse drug reactions of psychotropic drugs in psychiatric inpatient department of tertiary care hospital

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20180095 ◽

2018 ◽

Vol 7 (2) ◽

pp. 259

Author(s):

Aruna Gurung ◽

Jugalkishore B. Jaju ◽

Ganesh R. Pawar ◽

Shrikant C. Dharmadhikari ◽

Rajvardhan R. Solunke

Keyword(s):

Drug Utilization ◽

Adverse Drug Reactions ◽

Psychotropic Drugs ◽

Tertiary Care ◽

Psychiatric Inpatient ◽

Defined Daily Dose ◽

Care Hospital ◽

Drug Reactions ◽

Utilization Pattern ◽

Inpatient Department

Background: Mental disorders are now widely recognized as a major contributor to the global burden of disease. The drug use in psychiatric illness is a complex process and because of this the optimal benefits of drug therapy in patient care is not achieved. This often leads to increased cost of medical care, drug resistance, adverse effects and patient mortality. Hence, this study is undertaken to study the drug utilization pattern and adverse drug reactions of psychotropic drugs in psychiatric inpatient department of a tertiary care hospital.Methods: A prospective, observational study was undertaken from 1st February 2015 to 31st July 2016. A total of 250 prescriptions were analysed. Defined daily dose of the drugs were calculated. ADR’s were recorded in the format of the National Pharmacovigilance Programme of India (PvPI).Results: In 250 prescriptions most, common drug prescribed was antipsychotics (48.5%). Total drug utilization in terms of DDD/100 bed days was 669. The total number of adverse drug reactions observed was 8%. Antipsychotics were the most common class of psychotropic drugs causing ADR’s.Conclusions: In conclusion, it has been found that the psychotropic drugs used in our psychiatry department was rational and was based on clinical knowledge, expertise and the guidelines available in the field of psychiatric practice.

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DRUG UTILIZATION PATTERN IN OPTHALMOLOGY DEPARTMENT AT A TERTIARY CARE HOSPITAL

International Research Journal of Pharmacy ◽

10.7897/2230-8407.04840 ◽

2013 ◽

Vol 4 (8) ◽

pp. 205-210

Author(s):

Pooja Prajwal ◽

Mohandas Rai ◽

Sharath K Kumar ◽

Srinivas U Bhat ◽

Floyd Vernon Dsouza

Keyword(s):

Drug Utilization ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Utilization Pattern

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Drug utilization pattern in outdoor patients of pediatric tertiary care hospital: a cross sectional study

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20204502 ◽

2020 ◽

Vol 9 (11) ◽

pp. 1725

Author(s):

Sonal M. Parekar ◽

Girish K. Maindarkar ◽

Vishal V. Maindarkar

Keyword(s):

Drug Utilization ◽

Tertiary Care ◽

Cross Sectional Study ◽

Drug Formulation ◽

Oral Drug ◽

Care Hospital ◽

Pediatric Hospital ◽

Sectional Study ◽

Utilization Pattern ◽

Cross Sectional

Background: Drug utilization study is essential, as safe and effective therapeutic regimen in paediatric population is challenging. Pattern of use of drugs in pediatrics vary as compared to adults, also there is limited data available. The objective of this study was to study drug utilization pattern in pediatric patients attending pediatric outpatient department of Maindarkar pediatric hospital, Latur.Methods: A cross sectional study was carried out for a period of six months from September 2019 to February 2020, by analysing a total 1000 prescriptions of patients who had visited the OPD of Maindarkar pediatric hospital. Prescriptions were selected by simple random sampling method.Results: In our study, out of the total of 1000 prescriptions, 244 (24.4%) were of neonates, 556 (55.6%) were of infants (1 month to 1 year) and 200 (20%) were of children above 1 year. 547 (54.7%) prescriptions were of male patients and 453 (45.3%) were of female patients. The most frequent classes of drugs prescribed were nonsteroidal anti-inflammatory drugs 704 (70.4%), followed by drugs used for respiratory disorders 655 (65.5%) and supplements (60%). Antimicrobials were prescribed in 498 (49.8%) prescriptions. The average number of drugs per prescription was 2.45. About two third of all the prescribed drugs (74.41%) were from national essential medicine list. Most of the prescriptions had oral drug formulation 825 (82.5%) followed by inhalational 208 (20.8%) followed by injectables 150 (15%). All the drugs were prescribed by brand names.Conclusions: Our study helps health-care system to understand, interpret and improve prescribing, administration, to minimize adverse events and promote rational use of medicines.

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Drug utilization pattern of antimicrobials in intensive care unit of a tertiary care teaching hospital

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20204103 ◽

2020 ◽

Vol 9 (10) ◽

pp. 1594

Author(s):

Saswat Satapathy ◽

Yajnesh P. Sahu ◽

Ashok K. Panigrahi ◽

Bhabagrahi Rath ◽

Ananta N. Patra

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Drug Utilization ◽

Drug Prescription ◽

Tertiary Care ◽

Quality Of Healthcare ◽

Cross Sectional Study ◽

Utilization Pattern ◽

Prescribing Practices ◽

Cross Sectional

Background: The intensive care unit is a setting where the multiple medications are prescribed to patients. Antimicrobials are heavily prescribed in the ICUs, which in turn enhance the risk of antimicrobial resistance, increase the side effects and increases the cost of treatment. Drug utilization study is a component of medical auditing that aims to monitor and evaluate the drug prescription patterns and to suggest necessary modifications in the prescribing practices to achieve rational therapeutic practice.Methods: A cross-sectional study was conducted in which data of patients admitted to ICU during the period from June 2019 to August 2019 was collected from the Medical Record Section of the hospital. Drug utilization pattern of antimicrobials in ICU was analyzed.Results: Out of 90 patients, 60 were males and 30 were females. The average duration of stay in ICU was 7.53 days. The most common antibiotic prescribed was ceftriaxone followed by piperacillin and tazobactam with DDD/100 bed days of 24.2 and 17.3 respectively.Conclusions: In this study, the results appeared to be similar to those reported in previous studies. However, prescription protocols need to be addressed to guide appropriate use of antimicrobials in the ICU setting. Therefore, it is necessary to conduct drug utilization research to understand the drug consumption and for implementation of protocols to improve the quality of healthcare.

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Drug utilization pattern and appropriateness of prescription in IPD geriatric patients in a tertiary care teaching hospital

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20205538 ◽

2020 ◽

Vol 10 (1) ◽

pp. 55

Author(s):

Shuchisuta P. Pathy ◽

Sachchidanand Pandey ◽

Bhabagrahi Rath ◽

Rinu Rani Dash

Keyword(s):

Drug Use ◽

Drug Utilization ◽

Geriatric Patients ◽

Tertiary Care ◽

World Health ◽

Potentially Inappropriate Medications ◽

Utilization Pattern ◽

Geriatric Population ◽

Prescribing Indicators ◽

Inappropriate Medications

Background: Drug utilization research provides insights into different aspects of drug use and drug prescribing such as pattern, quality, determinants and outcomes of drug use. Polypharmacy is considered to be hazardous for the elderly, because of their greater vulnerability to drugs and multiple drug use. Prescription of potentially inappropriate medications (PIMs) has been found to be a common cause of morbidity and mortality among the geriatric population and has necessitated the creation of criteria for the safe use of medicines among them. Objectives of the study were to assess the drug utilization pattern in geriatric patients and analyse their prescriptions as per the World Health Organization (WHO) core prescribing indicators and STOPP and START criteria.Methods: An observational, cross-sectional study was conducted from May 2019 to August 2019 in inpatient department of general medicine of VIMSAR, Burla. Prescriptions of ≥65 year patients were collected and documented by active surveillance from the medicine ward.Results: Majority of the patients were in age group of 65-75. Stroke is the more common comorbidities among geriatric population. Average number of medication per prescription is 5.42. About 78.74% of drugs are injectable. The percentage of antibiotics prescribed to patient is 27.75%. Based on STOPP criteria potentially inappropriate medications PIM is 7% and START criteria PIM is 29%.Conclusions: Our study suggests that prevalence of polypharmacy was high which is usually unavoidable in geriatric patients and less PIM is suggestive of adherence to WHO core prescribing indicators, and prescription of drugs as per STOPP and START guidelines are indicative of scope for improvement.

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