scholarly journals Protective Effects of Vitamin C against Nicotine-Induced Oxidative Damage of Rat Liver and Kidney

2014 ◽  
Vol 8 (12) ◽  
pp. 50-63 ◽  
Author(s):  
Ghada S Mahmoud ◽  
Keyword(s):  
Vitamin C ◽  
Oxidative Damage ◽  
Rat Liver ◽  
Protective Effects ◽  
Liver And Kidney

scholarly journals Amelioration of Cadmium-induced Oxidative Damage in Wistar Rats by Vitamin C, Zinc and N-Acetylcysteine

2021 ◽  
Author(s):  
Venkataramanaiah Poli ◽  
Renuka Madduru ◽  
Srinivasulu Reddy Motireddy
Keyword(s):  
Antioxidant Enzymes ◽  
Vitamin C ◽  
Oxidative Damage ◽  
Wistar Rats ◽  
Tissue Respiration ◽  
Protective Effects ◽  
Cd Toxicity ◽  
Lipid Oxidation Products ◽  
Liver And Kidney ◽  
The Impact

Abstract The present study was performed to determine the protective effects of Vitamin C, Zinc and N-Acetylcysteine individually or in combinations with Cd, to monitor amelioration capability against Cd-induced oxidative damage in Wistar rats. Nine groups of rats were studied as experimental group. The present experiment was conducted for 45 days. Liver and kidneys were excised for biochemical determinations through assaying of antioxidant enzymes and lipid oxidation products to assess the impact of Cd-toxicity and its amelioration by co-administration of Vitamin C, Zinc and NAC along with Cd. Basal Metabolic rates, Tissue Respiration rates of liver and kidney were found to be significantly decreased (p < 0.05) during Cd toxicity. Serum biochemical parameters were also found to be significantly altered to cope up with Cd toxicity. All the antioxidant enzymes and products were significantly inhibited (p < 0.05) or elevated in rat liver and kidney tissues during Cd-induced toxicity. Whereas with co-administration of Vitamin C, Zinc and NAC, into rats clearly demonstrates the amelioration of oxidative damage induced by Cd-toxicity. From the results obtained in the present study all the agents tested had protective effects against Cd-induced oxidative damage.

Protective effects of ethyl acetate fraction ofLawsonia inermisfruits extract against carbon tetrachloride-induced oxidative damage in rat liver

2013 ◽  
Vol 32 (4) ◽  
pp. 694-706 ◽  
Author(s):  
Anis Ben Hsouna ◽  
Saoudi Mongi ◽  
Gérald Culioli ◽  
Yves Blache ◽  
Zohra Ghlissi ◽  
...  
Keyword(s):  
Carbon Tetrachloride ◽  
Oxidative Damage ◽  
Ethyl Acetate ◽  
Rat Liver ◽  
Ethyl Acetate Fraction ◽  
Protective Effects

Acute effects of methiocarb on oxidative damage and the protective effects of vitamin E and taurine in the liver and kidney of Wistar rats

2012 ◽  
Vol 29 (1) ◽  
pp. 60-71 ◽  
Author(s):  
Sibel Ozden ◽  
Betul Catalgol ◽  
Selda Gezginci-Oktayoglu ◽  
Ayse Karatug ◽  
Sehnaz Bolkent ◽  
...  
Keyword(s):  
Vitamin E ◽  
Oxidative Damage ◽  
Wistar Rats ◽  
Protective Effects ◽  
Acute Effects ◽  
Liver And Kidney

Oxidative Damage to Nuclear DNA in Hyperthyroid Rat Liver: Inability of Vitamin C to Prevent the Damage

2004 ◽  
Vol 67 (5) ◽  
pp. 413-420 ◽  
Author(s):  
Gülnur Andican ◽  
Remise Gelişgen ◽  
Sabiha Civelek ◽  
Arzu Seven ◽  
Oktay Seymen ◽  
...  
Keyword(s):  
Vitamin C ◽  
Oxidative Damage ◽  
Rat Liver ◽  
Nuclear Dna
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