EXPRESS: Consonant and vowel transpositions effects during reading development: a study on Italian children and adults

Recently, Colombo, Spinelli, and Lupker (2020), using a masked transposed letter (TL) priming paradigm, investigated whether consonant/vowel (CV) status is important early in orthographic processing. In four experiments with Italian and English adults, they found equivalent TL priming effects for CC, CV, and VC transpositions. Here, we investigated that question with younger readers (age 7 to 10) and adults, as well as whether masked TL priming effects might have a phonological basis. That is, because young children are likely to use phonological recoding in reading, the question was whether they would show TL priming that is affected by CV status. In Experiment 1, target words were preceded by primes in which two letters (either CV, VC, or CC) were transposed versus substituted (SL). We found significant TL priming effects, with an increasing developmental trend, but, again, no letter type by priming interaction. In Experiment 2 the transpositions/substitutions involved only pairs of vowels with those vowels having either diphthong or hiatus status. The difference between these vowel clusters is only phonological, thus the question was would TL priming interact with this factor. TL priming was again found with an increasing trend with age, but there was no vowel cluster by priming interaction. There was, however, an overall vowel cluster effect (slower responding to words with hiatuses) which decreased with age. The results suggest that TL priming only taps the orthographic level, and that CV status only becomes important at a later phonological level.

An Empirical Analysis on the Volatility of Return of CSI 300 Index

In order to better observe the trend of the stock market, this paper selects the daily closing price data of CSI 300 index from April 12, 2016 to September 30, 2021, and makes an empirical analysis on the logarithmic return of CSI 300 index. It is found that: (1) the return series of the CSI 300 index shows the statistical characteristics of peak, thick tail, bias, asymmetry and persistence. The ARMA (2,3) model can effectively fit the yield series and predict the future trend to a certain extent. (2) The residuals of ARMA model show obvious cluster effect and ARCH effect (conditional heteroscedasticity). GARCH (1,1) model can better fit the conditional heteroscedasticity, so as to eliminate the ARCH effect. (3) By constructing GARCH (1,1) model, it is found that the sum of ARCH term coefficient and GARCH term coefficient is very close to 1, indicating that GARCH process is wide and stable, the impact on conditional variance is lasting, and the market risk is large, that is, the impact plays an important role in all future forecasts.

“To be or not to be” located in a cluster?—A descriptive meta-analysis of the firm-specific cluster effect

In the twenty-first century, clusters can be observed in most developed economies. However, the scientific results regarding the effect of clusters on firm performance are highly contradictive. The inconsistencies in the empirical results make it difficult to infer general conclusions about the firm-specific cluster effect, or in other words, the effect from being located in a cluster on firm performance (e.g. derived through the externalities within clusters). Therefore, this paper aims to reconcile the contradictory empirical findings. It investigates whether the prevalent assumption that clusters are a beneficial location for firms is unconditionally true or whether doubts about the alleged positive effect of clusters on firm performance are justified. By conducting a descriptive meta-analysis of the empirical literature, based on four different performance variables from four separate publication databases, the study investigates the direction of the effect as well as possible moderating influences. We find evidence for a rather positive firm-specific cluster effect. However, we identify several variables from the micro-, meso- and macro-level that directly or interactively moderate the relationship between clusters and firm success. For example, the results demonstrate that a negative firm-specific cluster effect occurs more frequently in low-tech industries than in high-tech industries. “To be or not to be” located in a cluster is therefore not the question, but it rather depends on the specific conditions.

Understanding variations and influencing factors on length of stay for T2DM patients based on a multilevel model

Aim Shortening the length of stay (LOS) is a potential and sustainable way to relieve the pressure that type 2 diabetes mellitus (T2DM) patients placed on the public health system. Method Multi-stage random sampling was used to obtain qualified hospitals and electronic medical records for patients discharged with T2DM in 2018. A box-cox transformation was adopted to normalize LOS. Multilevel model was used to verify hospital cluster effect on LOS variations and screen potential factors for LOS variations from both individual and hospital levels. Result 50 hospitals and a total of 12,888 T2DM patients were included. Significant differences in LOS variations between hospitals, and a hospital cluster effect on LOS variations (t = 92.188, P<0.001) was detected. The results showed that female patients, patients with new rural cooperative’ medical insurance, hospitals with more beds, and hospitals with faster bed turnovers had shorter LOS. Conversely, elderly patients, patients with urban workers’ medical insurance, patients requiring surgery, patients with the International Classification of Diseases coded complication types E11.1, E11.2, E11.4, E11.5, and other complications cardiovascular diseases, grade III hospitals, hospitals with a lower doctor-to-nurse ratio, and hospitals with more daily visits per doctor had longer LOS. Conclusions The evidence proved that hospital cluster effect on LOS variation did exist. Complications and patients features at individual level, as well as organization and resource characteristics at hospital level, had impacted LOS variations to varying degrees. To shorten LOS and better meet the medical demand for T2DM patients, limited health resources must be allocated and utilized rationally at hospital level, and the patients with the characteristics of longer LOS risk must be identified in time. More influencing factors on LOS variations at different levels are still worth of comprehensive exploration in the future.

Surface plasmon resonance study for a reliable determination of the affinity constant of multivalent grafted beads

Thermodynamic and kinetic parameters of the multivalent galactose beads are determined via SPR. The results show that the glycoside cluster effect influences the affinity toward the lectin and it is crucial for mimicking the biological samples.

Prevalence and Associated Lifestyle Factors of Suboptimal Health Status among Chinese Children Using a Multi-Level Model

Chinese children are facing health challenges brought by chronic non-communicable diseases, such as physical problems and psychological related health problems. Childhood represents a critical life period when the long-term dietary and lifestyle behaviors are formed. It is necessary to survey the prevalence of suboptimal health status (SHS) among Chinese children and to research the relationship between SHS and lifestyles. This study aimed to examine the prevalence of SHS among Chinese children using a large-scale population survey sample covering school students and nonstudent children, and clarified the relationships between SHS and lifestyle factors using multi-level models controlled for the cluster effect of location and the confounding effect of demographics. Multi-level generalized estimating equation models were used to examine the relationships between SHS and lifestyle factors. Prevalence ratios (PR) and 95% confidence intervals (CI) were used to assess the strength of these relationships. Of the 29,560 children, 14,393 reported one or more SHS symptoms, giving a SHS prevalence of 48.69%. The prevalence of SHS for boys (46.07%) was lower than that for girls (51.05%). After controlling for the cluster effect of living areas and confounding effect of demographic characteristics, lifestyle factors associated with SHS were: less sleep duration, current smokers (PR = 1.085, 95%CI: 1.027–1.147), current drinkers (PR = 1.072, 95%CI: 1.016–1.131), children’ parents suffering from chronic diseases (PR = 1.294, 95%CI: 1.179–1.421), poor sleep quality (PR = 1.470, 95%CI: 1.394–1.550), stress (PR = 1.545, 95%CI: 1.398–1.707), negative life events (PR = 1.237, 95%CI: 1.088–1.406), hypertension (PR = 1.046, 95%CI: 1.009–1.084), unhealthy diet choice (PR = 1.091, 95%CI: 1.051–1.133) and irregular meal time (PR = 1.210, 95%CI: 1.163–1.259). Children who could exercise regularly (PR = 0.897, 95%CI: 0.868–0.927) and those with regular medical checkup (PR = 0.891, 95%CI: 0.854–0.929) were associated with lower prevalence probability of SHS. SHS has become a serious public health challenge for Chinese children. Unhealthy lifestyles were closely associated with SHS. Implementation of preventative strategies are needed to reduce the potential SHS burden associated with these widespread high-risk unhealthy lifestyle behaviors.