Modelling and Optimisation of UHF band EW Based WTA Problem within the Scope of Threat Assessment

The classical weapon target allocation (WTA) problem has been evaluated within the scope of electronic warfare (EW) threat assessment with an electromagnetic effect-based jammer- tactical radio engagement approach. As different from the literature, optimum allocation of non-directional jammers operating at different operating UHF frequencies under constraints to RF emitters is aimed in this study. The values of the targets are modelled using an original threat assessment algorithm developed that takes into account operating frequencies, jamming distance, and weather conditions. The computed jammer-target effect matrix has been solved under different scenarios according to the efficiency and cost constraints. It is seen at the end of the simulations that the allocation results for EW applications largely depend on the effect ratio used. The better results are taken in the case of under 0.5 effect ratio. Finally, jammer-radio allocation problem specified at the suggested model is solved successfully and effectively.

Differential Effects of Acute and Chronic Antagonist And An Irreversible Antagonist Treatment On Cocaine Self-Administration Behavior in Rats

According to pharmacological theory, the magnitude of an agonist-induced response is related to the number of receptors occupied. If there is a receptor reserve, when the number of receptors is altered the fractional occupancy required to maintain this set number of receptors will change. Therefore, any change in dopamine receptor number will result in a change in the concentration of cocaine required to induce the satiety response. Rats that self-administered cocaine were treated with the irreversible monoamine receptor antagonist, EEDQ, or were infused continuously for 14 days with the D1-like antagonist, SCH23390, treatments known to decrease or increase, respectively, the number of dopamine receptors with a concomitant decrease or increase in response to dopaminergic agonists. The rate of maintained cocaine self-administration increased or decreased in rats treated with EEDQ or withdrawn from chronic SCH23390 infusion, respectively. After EEDQ treatment, the effect ratio of a single dose of SCH23390 or eticlopride were unchanged, indicating that the same dopamine receptor populations mediated the accelerated cocaine self-administration. The satiety threshold likely corresponds to a specific number of activated dopamine receptors. Changing the receptor reserve is a key determinant of the rate of cocaine self-administration because the resulting increased or decreased concentration of cocaine results in an accelerated or decelerated rate of cocaine elimination as dictated by first-order kinetics. Changes in dopamine receptor number that may occur after continuous treatment with antagonists may account for the apparent lack of efficacy of these antagonists in clinical trials for cocaine use disorder.

Thundercloud Electrostatic Field Measurements during the Inflight EXAEDRE Campaign and during Lightning Strike to the Aircraft

The AMPERA (Atmospheric Measurement of Potential and ElectRic field on Aircraft) electric field network was integrated on the Falcon 20 (F20) of SAFIRE (the French facility for airborne research) in the framework of EXAEDRE (EXploiting new Atmospheric Electricity Data for Research and the Environment) project. From September 2018, an in-flight campaign was performed over Corsica (France) to investigate the electrical activity in thunderstorms. During this campaign, eight scientific flights were done inside or in the vicinity of a thunderstorm. The purpose of this paper is to present the AMPERA system and the atmospheric electrostatic field recorded during the flights, and particularly during the pass inside electrified clouds, in which the aircraft was struck by lightning. The highest value of atmospheric electrostatic field recorded during these flights was around 79 kV·m−1 at 8400 m of altitude. A normalization of these fields is done by computing the reduced atmospheric electrostatic field to take into account the altitude effect (ratio between the atmospheric electrostatic field and the air density). Most of the significant values of reduced atmospheric electrostatic field magnitude retrieved during this campaign occur between around 5.5 and 9.5 km and are included between 50 and 100 kV·m−1. The highest value measured of the reduced atmospheric electrostatic field is 194 kV·m−1 during the lightning strike of the F20. The merging of these results with data from former campaigns suggests that there is a threshold (depending of the aircraft size) for the striking of an aircraft.

Air-Sea CO2 Exchange in the Strait of Gibraltar

The seasonal and spatial variability of the CO2 system and air-sea fluxes were studied in surface waters of the Strait of Gibraltar between February 2019 and March 2021. High-resolution data was collected by a surface ocean observation platform aboard a volunteer observing ship. The CO2 system was strongly influenced by temperature and salinity fluctuations forced by the seasonal and spatial variability in the depth of the Atlantic–Mediterranean Interface layer and by the tidal and wind-induced upwelling. The changes in seawater CO2 fugacity (fCO2,sw) and fluxes were mainly driven by temperature despite the significant influence of non-thermal processes in the southernmost part. The thermal to non-thermal effect ratio (T/B) reached maximum values in the northern section (>1.8) and minimum values in the southern section (<1.30). The fCO2,sw increased with temperature by 9.02 ± 1.99 μatm °C–1 (r2 = 0.86 and ρ = 0.93) and 4.51 ± 1.66 μatm °C–1 (r2 = 0.48 and ρ = 0.69) in the northern and southern sections, respectively. The annual cycle of total inorganic carbon normalized to a constant salinity of 36.7 (NCT) was assessed. Net community production processes described 93.5–95.6% of the total NCT change, while air-sea exchange and horizontal and vertical advection accounted for <4.6%. The fCO2,sw in the Strait of Gibraltar since 1999 has been fitted to an equation with an interannual trend of 2.35 ± 0.06 μatm year–1 and a standard error of estimate of ±12.8 μatm. The seasonality of the air-sea CO2 fluxes reported the behavior as a strong CO2 sink during the cold months and as a weak CO2 source during the warm months. Both the northern and the southern sections acted as a net CO2 sink of −0.82 and −1.01 mol C m–2 year–1, respectively. The calculated average CO2 flux for the entire area was −7.12 Gg CO2 year–1 (−1.94 Gg C year–1).

Relationship Between Medical Students’ Empathy and Occupation Expectation: Mediating Roles of Resilience and Subjective Well-Being

Background: The occupation expectation of medical students can predict the possibility of their future employment in the medical industry, and empathy is the special ability of medical students in their study and career, which affects the development of their occupation expectation.Objective: To explore the relationship between resilience and subjective well-being between medical students’ empathy and occupation expectation and their internal mechanisms.Design: Data were collected from October 2020 to March 2021 using a paper questionnaire survey.Subjective: 586 medical students at a key medical university in Yunnan Province were invited to complete the survey.Main Measures: The Basic Empathy Scale, Connor-Davidson Resilience Scale, Subjective Well-Being Questionnaire, and Occupation Expectation Scale.Key Results: The empathy is intended to affect the occupation expectation of medical students through four paths. The direct path effect value is 0.073 (95% CI: 0.007∼0.217), the indirect path 1 effect value is 0.078 (95% CI: 0.022∼0.134), indirect path 2 effect value is 0.010 (95% CI: 0.005∼0.022), indirect path 3 effect value is 0.022 (95% CI: 0.0604∼0.039), all the confidence intervals do not contain 0, and the mediated effect ratio is 60.109%.Conclusion: Empathy has an impact on occupation expectation of medical students through the sequential mediating effects of resilience and subjective well-being. Medical colleges should fully consider the role of protective factors when cultivating and enhancing the occupation expectation of clinical medical students. Strengthening the intervention of emotional factors (empathy), self-regulating ability (psychological toughness) and cognitive factors (subjective well-being) is an important way to effectively establish professional values, improve occupation expectation of medical students and reduce the turnover rate of medical students.

Metabolomic Identification of Alpha-Ketoglutaric Acid Elevation in Pediatric Chronic Graft-versus-Host Disease

Chronic graft versus host disease (cGvHD) is the most common cause for non-relapse mortality post allogenic hematopoietic stem cell transplant (HSCT). However, there are no well-defined biomarkers for cGvHD or late acute GvHD (aGvHD). This study is a longitudinal evaluation of metabolomic patterns of cGvHD and late aGvHD in pediatric HSCT recipients. A quantitative analysis of plasma metabolites was performed on 222 evaluable pediatric subjects from the ABLE/PBMTC1202 study. We performed a risk-assignment analysis at day+100 on subjects who later developed either cGvHD or late aGvHD after day 114 to non-cGvHD controls. A second analysis at diagnosis used fixed and mixed multiple regression to compare cGvHD at onset to time matched non-cGvHD controls. A metabolomic biomarker was considered biologically relevant only if it met all three selection criteria: a) p value ≤0.05, b) effect ratio of ≥1.3 or ≤0.75, and c) receiver operator characteristic AUC ≥0.60. We found a consistent elevation in plasma alpha-ketoglutaric acid before (Day + 100) and at the onset of cGvHD, not impacted by cGvHD severity, pubertal status, or previous aGvHD. In addition, late aGvHD had a unique metabolomic pattern at day+100 compared to cGvHD. Additional metabolomic correlation patterns were seen with the clinical presentation of pulmonary, de novo, and progressive cGvHD. Alpha-ketoglutaric acid emerged as the single most significant metabolite associated with cGvHD, both in the day +100 risk-assignment and later diagnostic onset analysis. These distinctive metabolic patterns may lead to improved subclassification of cGvHD. Future validation of these exploratory results are needed.

Synthesis of margarine fat from sesame oil and palm stearin by chemical interesterification

The production of margarine fat is not only intended to be free from Trans Fatty Acid (TFA) but is also expected to have a higher quality from a nutritional aspect. In this research, margarine fat from sesame oil (SO) and palm stearin (PS) by a chemical interesterification was synthesized. Chemical interesterification is one of the processes used to modify the physico-chemical characteristics of oils and fats. An attempt to chemical-restructure palm stearin and sesame oil to form margarine fat which is suitable for margarine was investigated using sodium methoxide as a catalyst. The effect ratio of PS/SO in color, slip melting point, solid fat index, texture and triacylglycerols (TAGS) profile of margarine fat were studied in research. This research was conducted by three major stages; characterization of sesame oil and palm stearin, synthesis of margarine fat by physical blending and chemical interesterification, and characterization of margarine fat. This study used a Completely Randomized Design (CRD) with one factor, namely the ratio of sesame oil and palm stearin. Margarine fat produced with different variations of the raw material concentration (% w/w SO:PS = 30:70; 40: 60; 50:50, 60:40, and 70:30). Chemical interesterification caused: rearrangement of triacylglycerols, reduction of S3 and U3 and increase in S2U and U2S type TAGs content of all blend, resulting in lowering of melting point, solid fat index and increase texture. Margarine fat in the % ratio of SO:PS = 60:40, has a similar characteristic (texture, slip melting point, solid fat index, and TAGS profiles) which margarine commercial, so has the potential to be developed in the manufacture margarine industry

Exploring the Role of Social Support between Discharge Teaching and Readiness for Discharge in Ocular Fundus Disease Patients: A Cross-Sectional Study

Background. This study aims to evaluate the quality of discharge teaching and readiness for discharge of fundus disease patients treated with day surgery and understand the role of social support between them. Methods. This was a cross-sectional descriptive correlational survey. Through convenient sampling, fundus disease patients treated with day surgery from Zhongshan Ophthalmic Center, China, were recruited. Data were collected using demographic and disease-related information, quality of discharge teaching scale, readiness for hospital discharge scale, and social support scale. Results. 255 fundus disease patients treated with day surgery were recruited at last. The mean total score of readiness for discharge, quality of discharge teaching, and social support in patients with fundus disease were 157.91 (SD = 26.68), 122.97 (SD = 21.55), and 36.32 (SD = 7.60), respectively. Participants with stronger social support had better discharge teaching and then had higher readiness for discharge. Social support played a partial mediator role in the relationship between discharge teaching and readiness for discharge. The mediation effect ratio was 5.5%. Conclusions. The quality of discharge teaching and social support among fundus disease patients who underwent day surgery was relatively high, and readiness for discharge was good. Social support is essential for the quality of discharge teaching and the improvement of discharge readiness. Clinical nurses need to provide appropriate guidelines to help patients seek effective support and improve quality of discharge teaching to enhance the readiness for discharge of fundus disease patients treated with day surgery.

Decomposition Factors Household Energy Subsidy Consumption in Indonesia: Kaya Identity and LMDI Approach

For decades, the subsidy had prompted excessive and wasteful while offering little motivation to boost energy efficiency or reduce domestic greenhouse gas emissions. This paper aimed to measure household subsidy energy by examining the relationship between the other ten variables. The Logarithmic Mean Divisia Index (LMDI) and decomposition index were deployed to recognize the determinant effects that drive household's subsidy energy consumption. This study also presented an ARDL model applied. The robustness of the Granger Causality, Long-run, and Short-run causality during 1990-2017 was assessed. Based on LMDI, we found out that Population, Income Per Capita, Ratio National Renewal Energy over Fuel Fossil, Gross Capital Stock, Urban Household Consumption, and Ratio Household Subsidy were the positive factors that aggravate the change in household energy subsidy. The negative sign of Ratio National Energy Intensity effect, Ratio Fossil Renewal Energy effect, Ratio Capital Labour substitution, and Ratio Household over Labour Force signified the decreasing significance of less household energy subsidy. On the panel ARD-ECM, we identified a negative sign speed-of-adjustment and significant at 1%. It implied that all the ten variable effects were converging in the long run after an experience shocks. The equation parameters were considered stable since the CUSUM gets inside the two critical lines. Additional RESET test of the stability to ascertain whether the estimated model was linear or correctly specified has been performed.