Contact Residue for Simultaneous Removal of Vehicle’s Frequency and Surface Roughness in Scanning Bridge Frequencies Using Two Connected Vehicles

Two factors are critical to the effectiveness of the vehicle scanning method for bridge frequencies. One is the frequency of the test vehicle itself. This can be eliminated by using the vehicle–bridge contact point response calculated from the vehicle response. The other is the surface roughness of the bridge, which can be removed by using the residual response of two connected vehicles. In this paper, it is demonstrated for the first time that both vehicle’s frequency and surface roughness can be simultaneously eliminated using the contact residue of two connected vehicles. Theoretically, a formulation is presented for both the contact response and residues. In the numerical study, the contact response is demonstrated to outperform the vehicle response as more bridge frequencies can be identified, while the contact residue is verified to work well for various surface roughnesses, vehicle spacings, and bridge damping ratios. For damped bridges with rough surfaces, the contact residue enables us to extract the first three bridge frequencies.

Computational Investigation Of Structural Interfaces Of Protein Complexes With Short Linear Motifs

Protein complexes with short linear motifs (SLiMs) are known to play important regulatory functions in eukaryotes. In this investigation, I have studied the structures deposited in PDB with SLiMs. The structures Were grouped into three broad categories of protein-protein, protein-peptide and the rest as others. Protein-peptide complexes Were found to be most highly represented. The interfaces Were evaluated for geometric features and conformational variables. It was observed that protein-protein and protein-peptide complexes show characteristic differences in residue pairings, which Were quantified by evaluating normalized contact residue pairing frequencies. Interface residues adopt characteristic canonical residue conformations in the Ramachandran space, with a pronounced preference for positive ϕ conformations. It was observed that phosphorylated residues have an unusual propensity to adopt the unusual positive ϕ conformations at the interface.