Tunable luminescence and cytotoxicity of Samarium-doped calcium–strontium–hydroxyapatite for cell imaging

Samarium (Sm)-doped calcium–strontium–hydroxyapatite (Ca–Sr–HA:Sm) materials were designed and prepared, and the influence of Sr-introduction on the structure, photoluminescence (PL) and cytotoxicity of samples was revealed. The Sr-doping deduces the shift of some diffraction peaks to smaller angles and enlarges the particle size of samples. The typical red– orange emissions and corresponding luminescence quenching of Sm[Formula: see text] were observed, and the optimal luminescence performance appeared when [Formula: see text](Sr) = 7(Sr/Ca = 7/3) and quenching concentration closes to [Formula: see text](Sm) = 0.8 mol.%. The non-radiative transitions and energy transfers due to the dipole–dipole interactions between ions with different symmetry are essential to the luminescence and quenching of Sm[Formula: see text]. Furthermore, the viability values of human HepG2 cells are calculated larger than 90%, and the red–orange color emission was observed when the particles are incubated with cells.

Influence of Li+ ions on the physicochemical properties of nanocrystalline calcium–strontium hydroxyapatite doped with Eu3+ ions

In the present study, nanocrystalline Ca–Sr hydroxyapatites structurally modified with Li+ ions as well as co-doped with Eu3+ ions were prepared as biomaterials showing both regenerative and therapeutic functions.

Self-assembly pore-forming mechanism of foam boundary templates and the preparation of porous strontium hydroxyapatite microspheres by homogeneous precipitation

The preparation of porous SrHAp microspheres, and the self-assembly pore-forming process and mechanism of a foam boundary template were systematically presented.