This study focuses upon the influence between banking internal factors and economic macro on the Islamic banking profitability in Indonesia and Malaysia of the last seven years researches to determine profitability predictor variables of them. Meta-analysis techniques developed by Hunter et al. (1982) were performed to some existing studies. Profit and loss sharing financing and interest rates of BI have a significant correlation to the Indonesia Islamic banking profitability, while the Capital Adequacy Ratio (CAR), Non Performing Financing (NPF), Financing to Deposit Ratio (FDR), and inflation have nosignificant correlation. Meta-analysis result of Islamic banking in Malaysia shows that total asset, loan to total asset, equity to total asset, expenses management, loan loss reserve to gross loan, and money supply (M2) have a significant correlation to the profitability of Malaysia Islamic Banking, whilst liquidity (liq) and GDP have no significant correlation.