Analysis of Tear Fluid for Evaluation on the Concentration of the Generic Anti-Glaucoma Drug Betoptik using Multisensory Stripping Voltammetry and Multivariate Statistics

It is important to monitor the concentration of drugs after their instillation: this helps to find the right drug dosages. The proposed method is based on recognizing multidimensional images through the use of multidimensional statistics; the images are produced by multisensory electrochemical systems that provide reliable information about the tested objects. The measurements were carried out using a planar solid-state electrode. The test-system solution was a 0.05 М KCl solution, which contained the Zn2+, Cd2+, Рb2+, Cu2+ Со2+, and Hg2+ metal cations at the concentration of 5 10–5 M. A new electrochemical method for multisensory stripping voltammetry has been used to determine whether it is appropriate for determination of generic forms of the drug Betoptic, that is, Xonef, Betoftan, and Betalink EU in tear fluid. Measurements were carried out on a planar three-electrode interdigitated electrode. It has been shown that this method is effective for determination of the generics. The dynamics of changes in their concentrations over time were examined. After instillation of the generics in glaucoma patients, their concentrations in the Tear fluid remained unchanged within 12 h. The list of organic substances that can be determined by the method of multisensory stripping voltammetry has been extended.

MULTIDIMENSIONAL IMAGES OF SPACE: REVIEW OF THE VII INTERNATIONAL SCIENTIFIC CONFERENCE "GEOGRAPHY OF ART"

The international scientific conference «Geography of Art» has been considering the interaction of art and space for many years. The first conference was held in 2009. In 2021, the seventh conference was held in a hybrid format, which allowed scientists from remote places and other countries to be invited. The role of art in shaping the cultural landscape, cartographic, artistic, and literary images of the world, and concepts of space in art were discussed. Art creates the meanings of geographical objects of different levels, «sculpting» the semantic form of urban space. «Genius and Place» is a theme that reveals how artists, writers, and poets re-create the meanings of the places they are associated with. Literary geography and local texts are one of the dimensions of this problem. As usual, the conference was characterized by a broad interdisciplinary approach.

Image Segmentation by Image Foresting Transform with Boundary Polarity and Shape Constraints

Image segmentation, such as to extract an object from a background, is very useful for medical and biological image analysis. In this work, we propose new segmentation methods for interactive segmentation of multidimensional images, based on the Image Foresting Transform (IFT), by exploiting for the first time non-smooth connectivity functions (NSCF) with a strong theoretical background. The new algorithms provide global optimum solutions according to an energy function of graph cut, subject to high-level boundary constraints (polarity and shape). Our experimental results indicate substantial improvements in accuracy in relation to other state-of-the-art methods, using medical images by allowing the customization of the segmentation to a given target object.

LEGION BASED WEED EXTRACTION FROM UAV IMAGERY

Multispectral images are the types of images which consist of many different bands of data for further processing. Vegetation Indexing has Different bands which are combined in the multispectral images and are used to accentuate the vegetated areas. In this one combination is most commonly used LIKE Ratio Vegetation Indexing (RVI). But using UAV imagery this problem has been solved because in UAV the area covered or captured by the cameras would be very wide so that the whole plot or crop can be viewed or captured from the UAV imagery. Legion is a Model used to do Scene Analysis Task, Image Segmentation, Object Selection and Speech Segregation. In this Research work we used the Legion Network approach to Detect or Segregate the Unwanted Crops or Weed to increase the crop productivity by Detecting or Segregating the Unwanted Crops or Weed. We used UAVDJI Phantom 4 having RGB Sensor and Tetracam NIR Sensor to collect the data set. Then we used ImageJ and MATLAB for applying Legion Model algorithm to process and analyze the multidimensional images using linear differential equations which solves the correlation problem of synchronization and Segregation of UAV based crop images to Detect the Unwanted crops

Express Screening of Tear Fluid for Evaluation of the Concentration of Lanomax Using Multisensory Stripping Voltammetry and Multivariate Statistics

The drug concentrations monitoring is very important for finding the right dosage. The developed method is based on the recognition of multidimensional images, which are produced by multisensory electrochemical systems that provide reliable information on objects being tested, using multidimensional statistics. The measurements were carried out using a planar solid-state electrode. The test solution was a 0.05 M KCl solution, which contained the $ {\rm{Z}}{{\rm{n}}_2}^ + ,{\rm{C}}{{\rm{d}}_2}^ + ,{\rm{P}}{{\rm{b}}_2}^ + ,{\rm{C}}{{\rm{o}}_2}^ + $ and $ {\rm{H}}{{\rm{g}}_2}^ + $ metal cations in the concentration of 5 • 10−5 M. The efficiency of this method in determining lanosterol with accounting for changes in its concentration with over time has been demonstrated. In order to determine concentrations of Lanomax in tear fluid, a procedure for multisensory stripping voltammetry has been developed and tested. It has been shown that the effect of lacrimal fluid on metal dissolution currents in the test system lasts 12 hours after the Lanomax instillation.

Jefferson Lab Report

Jefferson Laboratory is finishing a major upgrade and has already started operations with the 12 GeV continuous electron beam. The main research direction is the study of the structure of hadrons, including a search for gluon excitations in the spectra of light mesons and baryons, and studies of multidimensional images of the nucleon. Studied of certain properties of atomic nuclei are also ongoing. There is also an active program of searching for effects beyond the Standard Model in parity-violating electron scattering, as well as a search for new particles.