This anthology challenges the notion that Latinas/os are newcomers to the Midwest by emphasizing that Latinas/os have resided in the region for over a century, and have contributed to the social, cultural, and economic dimensions of rural and urban Midwestern communities. Its eighteen interdisciplinary chapters and introduction essays explore issues of history, education, literature, art, and politics defining today’s Latina/o Midwest. Some contributors delve into the Latina/o revitalization of rural areas, where communities have launched bold experiments in dual-language immersion education while seeing integrated neighborhoods, churches, and sports teams become the norm. Others reveal metro areas as laboratories for emerging Latino subjectivities, places where for some, the term Latina/o itself corresponds to a new type of lived identity as different Latina/o groups interact in shared neighborhoods, schools, and workplace.