piecewise exponential model
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Author(s):  
Caroline Neuber-Pohl

AbstractGerman establishments heavily rely on the apprenticeship system for skill supply. With one in four apprenticeship contracts ending before successful completion, it is in the interest of establishments and policy-makers to determine factors, which reduce non-completion. This paper investigates the role of apprenticeship wages and income prospects after completion for apprenticeship non-completion in Germany. For this purpose, this study identifies incidences of apprenticeship non-completion in a large sample of administrative data on employment biographies and estimates a piecewise exponential model of the non-completion hazard with shared frailties by occupations. The results suggest a robust and significant association with both apprenticeship wages and skilled worker wages. All else at means, apprenticeships which are paid 5% more than the mean apprenticeship wage, on average have a 0.8 percentage points higher estimated survival rate. In turn, an apprenticeship expected to lead to a skilled job that is paid 5% above average, has an estimated survival rate, which is 3.1 percentage points higher on average. These findings highlight the importance of income prospects for apprenticeship non-completion.


2021 ◽  
Author(s):  
Erdachew Yitagesu Tesema ◽  
Enyiew Alemnew

Abstract Non-parametric survival analysis and piecewise exponential model (PEM) was used to estimate prevalence and incidence of goat mortality, to identify major clinical causes of morbidity and mortality related disease, and to investigate animal and environmental related risk factors affecting goat mortality at Ataye boer goat breeding and evaluation research site. A total of 671 kids and 347 adult (yearling) age goats were used for the analysis of non-parametric survival and piecewise exponential model for survival, mortality incidence rate and causes of morbidity and mortality analysis. The mortality incidence rate of kids and adult goats were 0.638 and 0.302 per animal year respectively. The 25th, 50th and 75th percentile of survival time of kids were 5, 157 and 1,274 days respectively and of adult goats were 280, 828 and 1,557 days respectively. The present mortality rate is relatively larger than reports of boer cross breeding and evaluation research sites in Ethiopia as well as goat mortality prevalence abroad. Gastro-intestinal related diseases, pneumonia, weak kid, agalactia, mismothering and hear water (cowdriosis) were most important causes of mortality. Constant piecewise exponential regression analysis of risk factors indicates that breed, kid birth weight (BWT), doe post-partum weight (PPWT), birth type, birth year and precipitation variables were associated with (p-value < 0.05) kid mortality rate. Pure boer kids compared with CHG cross boer goat, are 2.505 times at higher probability of mortality (p ≤ 0.001). A 1 kilo gram increase of kid birth weight and dam PPWT reduces mortality probability by 32.5% (p-value ≤ 0.001) and 6.4% (p-value ≤ 0.001) respectively. Twin birth kids are1.512 times higher rate of mortality (p-value = 0.001) compared with single born kids. A one-millilitre increment of 15 days average precipitation significantly reduces kid mortality by 7.8% (p-value ≤ 0.001). Fleshing of does during early meeting to improve the post-partum weight of does and kids is also important to reduce both kid and doe mortality at and after kidding. Immunization of new introduced and kids to common endemic diseases in the area, extensive control of ticks to breakdown heart water transmission and use of proper comfortable housing to reduce stress of goats is recommended. Improving nutrition particularly during scarce grazing and browsing feed availability is important to improving the health and reducing mortality of goats in intensively managed goat farms.


Neurology ◽  
2019 ◽  
Vol 94 (2) ◽  
pp. e190-e199 ◽  
Author(s):  
Jonathan Graff-Radford ◽  
Timothy Lesnick ◽  
Alejandro A. Rabinstein ◽  
Jeff Gunter ◽  
Jeremiah Aakre ◽  
...  

ObjectiveTo determine the incidence of cerebral microbleeds (CMBs) and the association of amyloid PET burden with incident CMBs.MethodsA total of 651 participants, age ≥50 years (55% male), underwent 3T MRI scans with ≥2 separate T2*-weighted gradient recalled echo sequences from October 2011 to August 2017. Eighty-seven percent underwent 11C Pittsburgh compound B (PiB) PET scans. Age-specific CMB incidence rates were calculated by using the piecewise exponential model. Using structural equation models (SEMs), we assessed the effect of amyloid load and baseline CMBs on future CMBs after considering the direct and indirect age, sex, vascular risk factors, and APOE effects.ResultsParticipants' mean age (SD) was 69.8 (10.0) years at baseline MRI, and 111 participants (17%) had ≥1 baseline CMB. The mean (SD) of the time interval between scans was 2.7 (1.0) years. The overall population incidence rate for CMBs was 3.6/100 person-years and increased with age: from 1.5/100 new CMBs at age 50 to 11.6/100 person-years at age 90. Using the piecewise exponential model regression, the incidence rates increased with age and the presence of baseline CMBs. The SEMs showed that (1) increasing age at MRI or carrying an APOE4 allele was associated with more amyloid at baseline, and higher amyloid, particularly occipital amyloid load, in turn increased the risk of a new lobar CMB; and (2) the presence of CMBs at baseline increased the risk of a lobar CMB and had a larger effect size than amyloid load.ConclusionsAge and APOE4 carrier status act through amyloid load to increase the risk of subsequent lobar CMBs, but the presence of baseline CMBs is the most important risk factor for future CMBs.


2018 ◽  
Vol 471 ◽  
pp. 193-200
Author(s):  
Filip WOLNY ◽  
Mariusz JAMRÓZ ◽  
Jerzy GASIŃSKI ◽  
Marek Marciniak ◽  
Mariusz KACZMAREK

Piezometric tests such as the slug test or PARAMEX test usually result in observing damped oscillations or exponential movement of the water level. However, during some tests, a bi-exponential response of the water table has been recorded. Bi-exponential movement may indicate the presence of a dual-permeability medium around the piezometer screen. Such medium is composed of two subdomains, each characterized by different hydraulic properties (including transmissivity, T). The paper aims to present two mathematical models – the piecewise exponential model and the bi-exponential model – which were applied in order to interpret the results of slug test conducted in heterogeneous sediments of the Bełchatów Lignite Mine. Theoretical background, interpretation algorithms and examples of dual transmissivity estimation for several chosen piezometers are presented. All necessary calculations were performed using Paramex 4 and MATLAB software. Furthermore, the limitations of the interpretation algorithms are discussed.


2017 ◽  
Vol 88 (5) ◽  
pp. 825-840 ◽  
Author(s):  
Yolanda M. Gómez ◽  
Diego I. Gallardo ◽  
Barry C. Arnold

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