robust implementation
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Author(s):  
Andrew J. Rosenblum ◽  
Christopher M. Wend ◽  
Zohaib Akhtar ◽  
Lori Rosman ◽  
Jeffrey D. Freeman ◽  
...  

Abstract Objective: Disasters of all varieties have been steadily increasing in frequency. Simultaneously, “big data” has seen explosive growth as a tool in business and private industries while opportunities for robust implementation in disaster management remain nascent. To more explicitly ascertain the current status of big data as applied to disaster recovery, we conducted an integrative literature review. Methods: Eleven databases were searched using iteratively developed keywords to target big data in a disaster recovery context. All studies were dual-screened by title and abstract followed by dual full-text review to determine if they met inclusion criteria. Articles were included if they focused on big data in a disaster recovery setting and were published in the English-language peer-reviewed literature. Results: After removing duplicates, 25,417 articles were originally identified. Following dual title/abstract review and full-text review, 18 studies were included in the final analysis. Among those, 44% were United States-based and 39% focused on hurricane recovery. Qualitative themes emerged surrounding geographic information systems (GIS), social media, and mental health. Conclusions: Big data is an evolving tool for recovery from disasters. More research, particularly in real-time applied disaster recovery settings, is needed to further expand the knowledge base for future applications.


2021 ◽  
Vol 5 (ICFP) ◽  
pp. 1-30
Author(s):  
Sandro Stucki ◽  
Paolo G. Giarrusso

The calculus of Dependent Object Types (DOT) has enabled a more principled and robust implementation of Scala, but its support for type-level computation has proven insufficient. As a remedy, we propose F ·· ω , a rigorous theoretical foundation for Scala’s higher-kinded types. F ·· ω extends F <: ω with interval kinds , which afford a unified treatment of important type- and kind-level abstraction mechanisms found in Scala, such as bounded quantification, bounded operator abstractions, translucent type definitions and first-class subtyping constraints. The result is a flexible and general theory of higher-order subtyping. We prove type and kind safety of F ·· ω , as well as weak normalization of types and undecidability of subtyping. All our proofs are mechanized in Agda using a fully syntactic approach based on hereditary substitution.


2021 ◽  
Author(s):  
Timothee O'Donnell ◽  
Charles H. Robert ◽  
Frederic Cazals

Tripeptide loop closure (TLC) is a standard procedure to reconstruct protein backbone conformations, by solving a zero dimensional polynomial system yielding up to 16 solutions. In this work, we first show that multiprecision is required in a TLC solver to guarantee the existence and the accuracy of solutions. We then compare solutions yielded by the TLC solver against tripeptides from the Protein Data Bank. We show that these solutions are geometrically diverse (up to 3 Angstroms RMSD with respect to the data), and sound in terms of potential energy. Finally, we compare Ramachandran distributions of data and reconstructions for the three amino acids. The distribution of reconstructions in the second angular space (φ2 , ψ2) stands out, with a rather uniform distribution leaving a central void. We anticipate that these insights, coupled to our robust implementation in the Structural Bioinformatics Library (https://sbl.inria.fr/doc/Tripeptide_loop_closure-user-manual.html), will boost the interest of TLC for structural modeling in general, and the generation of conformations of flexible loops in particular.


2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Vicente Leyton-Ortega ◽  
Alejandro Perdomo-Ortiz ◽  
Oscar Perdomo

2021 ◽  
Vol 13 (9) ◽  
pp. 5041
Author(s):  
Ayyagari Ramani ◽  
Borja García de Soto

Multiple sustainability standards and rating systems have been developed to draw attention to constructing sustainable buildings. The Pearl Rating System (PRS) is a mandate for all new construction projects in Abu Dhabi. Hence, it is important to understand the main components, advantages, and limitations of the PRS. The feasibility and the practical relevance of the PRS are still being studied. This paper addresses this gap and critically evaluates the PRS against some of the well-established rating systems like LEED and BREEAM. The analysis suggests that the PRS considers the cultural aspect of sustainability, in addition to the environmental, societal, and economic aspects. It was also found that most rating systems, including the PRS, have a very superficial inclusion of life cycle assessment (LCA). The paper finally concludes with other observations and outlook for a more robust implementation of the PRS.


Materials ◽  
2021 ◽  
Vol 14 (8) ◽  
pp. 1913
Author(s):  
Yousef Navidtehrani ◽  
Covadonga Betegón ◽  
Emilio Martínez-Pañeda

We present a simple and robust implementation of the phase field fracture method in Abaqus. Unlike previous works, only a user material (UMAT) subroutine is used. This is achieved by exploiting the analogy between the phase field balance equation and heat transfer, which avoids the need for a user element mesh and enables taking advantage of Abaqus’ in-built features. A unified theoretical framework and its implementation are presented, suitable for any arbitrary choice of crack density function and fracture driving force. Specifically, the framework is exemplified with the so-called AT1, AT2 and phase field-cohesive zone models (PF-CZM). Both staggered and monolithic solution schemes are handled. We demonstrate the potential and robustness of this new implementation by addressing several paradigmatic 2D and 3D boundary value problems. The numerical examples show how the current implementation can be used to reproduce numerical and experimental results from the literature, and efficiently capture advanced features such as complex crack trajectories, crack nucleation from arbitrary sites and contact problems. The code developed is made freely available.


10.2196/24359 ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. e24359
Author(s):  
Katy E Trinkley ◽  
Miranda E Kroehl ◽  
Michael G Kahn ◽  
Larry A Allen ◽  
Tellen D Bennett ◽  
...  

Background Limited consideration of clinical decision support (CDS) design best practices, such as a user-centered design, is often cited as a key barrier to CDS adoption and effectiveness. The application of CDS best practices is resource intensive; thus, institutions often rely on commercially available CDS tools that are created to meet the generalized needs of many institutions and are not user centered. Beyond resource availability, insufficient guidance on how to address key aspects of implementation, such as contextual factors, may also limit the application of CDS best practices. An implementation science (IS) framework could provide needed guidance and increase the reproducibility of CDS implementations. Objective This study aims to compare the effectiveness of an enhanced CDS tool informed by CDS best practices and an IS framework with a generic, commercially available CDS tool. Methods We conducted an explanatory sequential mixed methods study. An IS-enhanced and commercial CDS alert were compared in a cluster randomized trial across 28 primary care clinics. Both alerts aimed to improve beta-blocker prescribing for heart failure. The enhanced alert was informed by CDS best practices and the Practical, Robust, Implementation, and Sustainability Model (PRISM) IS framework, whereas the commercial alert followed vendor-supplied specifications. Following PRISM, the enhanced alert was informed by iterative, multilevel stakeholder input and the dynamic interactions of the internal and external environment. Outcomes aligned with PRISM’s evaluation measures, including patient reach, clinician adoption, and changes in prescribing behavior. Clinicians exposed to each alert were interviewed to identify design features that might influence adoption. The interviews were analyzed using a thematic approach. Results Between March 15 and August 23, 2019, the enhanced alert fired for 61 patients (106 alerts, 87 clinicians) and the commercial alert fired for 26 patients (59 alerts, 31 clinicians). The adoption and effectiveness of the enhanced alert were significantly higher than those of the commercial alert (62% vs 29% alerts adopted, P<.001; 14% vs 0% changed prescribing, P=.006). Of the 21 clinicians interviewed, most stated that they preferred the enhanced alert. Conclusions The results of this study suggest that applying CDS best practices with an IS framework to create CDS tools improves implementation success compared with a commercially available tool. Trial Registration ClinicalTrials.gov NCT04028557; http://clinicaltrials.gov/ct2/show/NCT04028557


2021 ◽  
pp. 1-31
Author(s):  
David Roos Launchbury ◽  
Luca Mangani ◽  
Ernesto Casartelli ◽  
Francesco Del Citto

Abstract In the industrial simulation of flow phenomena, turbulence modeling is of prime importance. Due to their low computational cost, Reynolds-averaged methods (RANS) are predominantly used for this purpose. However, eddy viscosity RANS models are often unable to adequately capture important flow physics, specifically when strongly anisotropic turbulence and vortex structures are present. In such cases the more costly 7-equation Reynolds stress models often lead to significantly better results. Unfortunately, these models are not widely used in the industry. The reason for this is not mainly the increased computational cost, but the stability and convergence issues such models usually exhibit. In this paper we present a robust implementation of a Reynolds stress model that is solved in a coupled manner, increasing stability and convergence speed significantly compared to segregated implementations. In addition, the decoupling of the velocity and Reynolds stress fields is addressed for the coupled equation formulation. A special wall function is presented that conserves the anisotropic properties of the model near the walls on coarser meshes. The presented Reynolds stress model is validated on a series of semi-academic test cases and then applied to two industrially relevant situations, namely the tip vortex of a NACA0012 profile and the Aachen Radiver radial compressor case.


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