Transcriptomic Analysis Reveals Key Genes Involved in Oil and Linoleic Acid Biosynthesis during Artemisia sphaerocephala Seed Development

Artemisia sphaerocephala seeds are rich in polysaccharides and linoleic acid (C18:2), which have been widely used as traditional medicine and to improve food quality. The accumulation patterns and molecular regulatory mechanisms of polysaccharides during A. sphaerocephala seed development have been studied. However, the related research on seed oil and C18:2 remain unclear. For this study, A. sphaerocephala seeds at seven different development stages at 10, 20, 30, 40, 50, 60, and 70 days after flowering (designated as S1~S7), respectively, were employed as experimental samples, the accumulation patterns of oil and fatty acids (FA) and the underlying molecular regulatory mechanisms were analyzed. The results revealed that oil content increased from 10.1% to 20.0% in the early stages of seed development (S1~S2), and up to 32.0% in mature seeds, of which C18:2 accounted for 80.6% of the total FA. FA and triacylglycerol biosynthesis-related genes jointly involved in the rapid accumulation of oil in S1~S2. Weighted gene co-expression network analysis showed that transcription factors FUS3 and bHLH played a critical role in the seed oil biosynthesis. The perfect harmonization of the high expression of FAD2 with the extremely low expression of FAD3 regulated the accumulation of C18:2. This study uncovered the gene involved in oil biosynthesis and molecular regulatory mechanisms of high C18:2 accumulation in A. sphaerocephala seeds; thus, advancing research into unsaturated fatty acid metabolism in plants while generating valuable genetic resources for optimal C18:2 breeding.

Study on Allergic Rhinitis of Artemisia Sphaerocephala

Objective: To explore the cause and feasibility of Artemisia ordosica allergic rhinitis. Methods: The main allergic causes of allergic rhinitis patients in Chifeng City of inner Mongolia were analyzed by a control method. Results: According to the results, Artemisia ordosica is the most important cause of allergic rhinitis in inner Mongolia. In addition, allergic history, asthma and other diseases, or animal hair and other factors can also increase the risk of patients with allergic rhinitis. Conclusions: Artemisia sphaerocephala is the main cause of allergic rhinitis. In recent years, allergic rhinitis has attracted the attention of international organizations, and the medical community has also studied more methods for the treatment of rhinitis, such as putting forward relevant traditional Chinese medicine (TCM) treatment methods.

The role of Se content in improving anti-tumor activities and its potential mechanism for selenized Artemisia sphaerocephala polysaccharides

Potent Se content-dependent anti-tumor activities of selenized Artemisia sphaerocephala polysaccharides by inhibition of tumor cell growth, and induction of mitochondria and death receptor-mediated apoptosis.