A Review on Nutritional and Dietary Intervention for Autism Spectrum Disorder

In this review we will be looking at nutritional intervention that can be used to achieve better results in management and treatment of autism spectrum disorder. Eating disorders are widespread in children with autism and autism spectrum disorders (ASDs). Their penchant for high-energy, low-nutrient foods can change their metabolism, creating an accumulation of reactive radicals and mental and physical deterioration. Probiotics, which are live microorganisms that provide a health benefit to the host when given in sufficient amounts, are gaining popularity as a potential treatment option for ASD. Studies shows that using of special and alternative nutritional diets can achieve better results for children with autism however some of these studies shows that the true effectiveness of such approaches is minimal if not lacking at all. It is recommended that there are many factors that play role in outcomes of theses treatment therefor more research is must in order to draw clear conclusion weather or not using of alternative diet is effective enough and if so, what’s the best guidelines for it.

Oxidized LDLs as Signaling Molecules

Levels of oxidized low-density lipoproteins (oxLDLs) are usually low in vivo but can increase whenever the balance between formation and scavenging of free radicals is impaired. Under normal conditions, uptake and degradation represent the physiological cellular response to oxLDL exposure. The uptake of oxLDLs is mediated by cell surface scavenger receptors that may also act as signaling molecules. Under conditions of atherosclerosis, monocytes/macrophages and vascular smooth muscle cells highly exposed to oxLDLs tend to convert to foam cells due to the intracellular accumulation of lipids. Moreover, the atherogenic process is accelerated by the increased expression of the scavenger receptors CD36, SR-BI, LOX-1, and SRA in response to high levels of oxLDL and oxidized lipids. In some respects, the effects of oxLDLs, involving cell proliferation, inflammation, apoptosis, adhesion, migration, senescence, and gene expression, can be seen as an adaptive response to the rise of free radicals in the vascular system. Unlike highly reactive radicals, circulating oxLDLs may signal to cells at more distant sites and possibly trigger a systemic antioxidant defense, thus elevating the role of oxLDLs to that of signaling molecules with physiological relevance.

Enhanced Photo–Fenton Removal Efficiency with Core-Shell Magnetic Resin Catalyst for Textile Dyeing Wastewater Treatment

Heterogeneous photo–Fenton reactions have been regarded as important technologies for the treatment of textile dyeing wastewaters. In this work, an efficient core-shell magnetic anion exchange resin (MAER) was prepared through in situ polymerization and used to remove reactive brilliant red (X-3B) in a UV–Fenton system. The MAER exhibited satisfactory removal efficiency for X-3B because of its highly effective catalytic activity. More than 99% of the X-3B (50 mg/L) was removed within 20 min in the UV–Fenton reaction. This is because the uniformly dispersed core-shell magnetic microsphere resin could suppress the aggregation of Fe3O4 nanoparticles and, thus, enhance the exposure of Fe reaction sites for catalytic reaction with H2O2. The good adsorption capacity of MAER also played an important role in promoting contact between X-3B and reactive radicals during the reaction. Mechanism research showed that hydroxyl radical (•OH) was the main reactive radicals for the removal of X-3B in the MAER UV–Fenton system. The MAER can be easily separated by a magnet after catalytic reactions. Moreover, the matrix effects of different substrates (Cl−, NO3−, SO42−, and humic acid) were investigated. The results showed that SO42− could be beneficial to improve the removal of X-3B but that the others decrease the removal. The MAER UV–Fenton also removed significant amounts of total organic carbon (TOC) for the X-3B solution and an actual textile dyeing industrial wastewater. The heterogeneous oxidation system established in this work may suggest prospects for practical applications in the treatment of textile dyeing wastewater.

Degradation of PFOS by a MnO2/H2O2 process

Degradation of PFOS by MnO2/H2O2 was systematically investigated and the role of reactive radicals on intermediate formation was characterized.