Current approaches to fate mapping and lineage tracing using image data

ABSTRACT Visualizing, tracking and reconstructing cell lineages in developing embryos has been an ongoing effort for well over a century. Recent advances in light microscopy, labelling strategies and computational methods to analyse complex image datasets have enabled detailed investigations into the fates of cells. Combined with powerful new advances in genomics and single-cell transcriptomics, the field of developmental biology is able to describe the formation of the embryo like never before. In this Review, we discuss some of the different strategies and applications to lineage tracing in live-imaging data and outline software methodologies that can be applied to various cell-tracking challenges.

Digital strategies for the valorisation of archival heritage

<p>20^th century pre-digital architectural archives are a current topic of interest for scholars involved in historical studies as well as those studying conservation, valorisation and communication. These vast archival heritages could be enhanced by the methodologies, techniques and tools offered by the digital revolution. The present proposal demonstrates this potential through the application of structure from motion techniques to a physical scale model that represents the Turin Horse Racing designed by Carlo Mollino. Moreover, the paper presents a comparison of different software, methodologies and modelling tools and suggests a design for virtual and on-site communication strategies. These strategies fuel new interrelations of knowledge and ideas, through which an archive can become a place of convergence between the real and the virtual.</p>

Structured Education for Sustainable Employment: Technology Enabled Queueing Theory Applications

Unemployment is a serious challenge that has been rising day by day. Skill development and creation of employment opportunities are key factors to address youth unemployment. This study emphasizes on the need for job-oriented education and to link education to employment. This study derives a mathematical model and tests the same using live university hiring data and attempts to integrate the three stakeholders, employers, education providers, and the young, each of whom have a unique approach, expectation, and understanding of the paradigm. Novel methodology inclusive of empirical evidence-based integration of objective fulfillment drafted into institutional pedagogy can help increase the success rate of education to employment from an Indian context especially Indian girls and women. The study outlines specific aspects of analytical intervention in this regard and focus-es on systematic training programs exclusively for vocational and skills amelioration executed to ad-dress this multidimensional challenge by adopting easily implementable software methodologies that are more easily implementable over a wide area network or an Internet-based application engine powered by information communication technology.