Personalized Image-Guided Therapies for Local Malignencies: Interdisciplinary Options for Interventional Radiology and Interventional Radiotherapy

Minimal-invasive interventions considerably extend the therapeutic spectrum in oncology and open new dimensions in terms of survival, tolerability and patient-friendliness. Through the influence of image-guided interventions, many interdisciplinary therapy concepts have significantly evolved, and this process is by far not yet over. The rapid progression of minimal-invasive technologies offers hope for new therapeutic concepts in the short, medium and long term. Image-guided hybrid-technologies complement and even replace in selected cases classic surgery. In this newly begun era of immune-oncology, interdisciplinary collaboration and the focus on individualized and patient-friendly therapies are crucial.

INSIDE INDUSTRY

Gilead enters new agreement with Medicines Patent Pool for access to medicines in developing world countries. Research alliance established to investigate new therapeutic concepts in the field of ubiquitin signaling biology. AstraZeneca and Kyowa Hakko Kirin partner on immune-oncology clinical study. AstraZeneca and Almirall enter strategic agreement in respiratory disease. Mundipharma appoints new President and Representative Director for its operations in Japan. A*STAR and Sumitomo Mitsui Banking Corporation sign MOU to support Japanese R&D collaborations with Singapore. Food Security summit on agricultural and nutrition challenges and solutions in Asia Pacific.

Disseminated intravascular coagulation in meningococcal sepsis

SummaryWe report on a man (age: 49 years), who died from severe meningococcal sepsis with disseminated intravascular coagulation (DIC), multiple organ dysfunction syndrome and extended skin necrosis. We discuss in detail the pathophysiology of the activation of coagulation and fibrinolysis during sepsis. The article discusses new therapeutic concepts in the treatment of disseminated intravascular coagulation in meningococcal sepsis, too.