A Self-Powered Flexible Biosensor for Human Exercise Intensity Monitoring

We report a flexible and portable biosensor for real-time monitoring body exercise intensity without power supply. The biosensor consists of ZnO NWs and flexible PDMS substrate. The flexible and portable biosensor can be attached to tester’s skin surface. Through piezoelectric signal, exercise intensity can be real-time monitored in sport process. After sweating, the sweat on the skin can flow to the modified ZnO NWs according to the set route through the guide channel of PDMS substrate. It also can monitor the variations of lactic acid concentration in sweat, and the output piezoelectric voltage depends on the sweat concentration, so as to judge the exercise intensity of sport. The biosensor can charge miniature capacitor and the capacitor can charge other small electronic equipment. This multidisciplinary study point out a new development direction of human exercise intensity monitoring and sport big data transmission in the field of sport science, and promote the development of self-powered flexible multifunctional nano-system.

Biosensing with DNAzymes

This article provides a comprehensive review of biosensing with DNAzymes, providing an overview of different sensing applications while highlighting major progress and seminal contributions to the field of portable biosensor devices and point-of-care diagnostics.

Electrochemical Biosensors for Point of care Applications

Biosensor refers to powerful and innovative analytical tool involving biological sensing element and transducer with broad range of applications, such as diagnosis, drug discovery, biomedicine, food safety and processing, environmental monitoring, security and defense. Recent advances in the field of biotechnology, microelectronics, and nanotechnology have improved the development of biosensors. Glucometers utilizing the electrochemical determination of oxygen or hydrogen peroxide employing immobilised glucose oxidase electrode seeded the discovery and development of biosensors. Molecular recognition based on geometry and forces of interaction play an important role in the biosensor development. The advent of nanotechnology led to highly efficient and sensitive biosensors. They also provide an effective immobilisation matrix for the various bioreceptors. Enzymatic and their mimetic (metalloporphyrin)-based biosensors for reactive oxygen, nitrogen species and cytochrome c will also be discussed. The role of antibodies and their applications in immunosensors development for cytochrome c and superoxide dismutase will be highlighted. The electrochemical biosensors are less expensive, miniaturised and used for point-of-care applications. Further, the fabrication of labVIEW based virtual biosensor instrumentation and microcontroller based portable biosensor for wide variety of applications also devices will be presented.