Market access of Chinese patent medicine products to healthcare security system in China: implications for international integration of traditional medicine into health systems

Background China has introduced a series of polices and practice to manage the market access of Chinese patent medicine (CPM) products into its healthcare security system, which is less analyzed and reported in current literature. Therefore, this paper aimed to investigate the mechanisms managing market access of CPM products into healthcare security system in China, expecting to provide implications for international integration of traditional medicine products into health systems. Method This paper used a documentary analysis approach as a qualitative research method. Data were collected from four sources and analyzed in a thematic way. Results Four mechanisms to manage entry, price adjustment, and exit of innovative brand and generic CPM products are identified, including: (1) price negotiation, mechanism of new entry of innovative brand CPM products into the national reimbursement list; (2) price re-negotiation, mechanism of price adjustment of innovative brand CPM products within the national reimbursement list; (3) mass procurement, mechanism of generic CPM products to healthcare security system; and (4) direct removal, mechanism of removal from the national reimbursement list. Conclusions China has established market access framework of CPM products by focusing on price negotiation for innovative brand CPM products and mass procurement for generic CPM products. Further studies of CPM products based real-world data are needed to provide clinical and pharmacoeconomic evidence to support market access of CPM products into healthcare security systems.

Cheers! Selling Health and Happiness: Advertising Alcohol in New Zealand, c.1900-1945.

<p>Abstract At the turn of the 20th century New Zealand’s newspapers were filled with advertising material offering information on a wide variety of products. Among these advertisements were those for alcohol, a commodity which the advertisements claimed to have multiple benefits, including those of a restorative and curative nature. This thesis will examine how two product groups, alcoholic beverages claiming medicinal value, and patent medicines containing alcohol, were advertised in selected New Zealand newspapers and magazines during the years 1900-1945. The advertising of these two groups was, in many ways, similar. Both used evocative text and images, with the images changing from drawn illustrations to photographs, and both targeted groups, linking these to specific drinks. For example, tonic wine advertising was aimed at women suffering from psychological distress, while beer and spirit advertisements targeted men and sporting codes, and patent medicine advertisements were designed to attract mothers and those suffering from respiratory illnesses. While both alcohol and patent medicines were subject to legislation this was not always effective. The Quackery Act 1908, which should have impacted on both alcohol and patent medicine advertising had no effect on either group. Patent medicine advertisers however, responded to the Physical Welfare Recreation Act 1937, and the Social Welfare Act 1938 with images of active, healthy children. The Medical Advertisements Act 1942 impacted immediately on alcohol advertising. but was not as successful with patent medicines. Both groups had significant changes affecting their advertising. For example, patent medicine advertising was dramatically altered by the discovery of vitamins. This, to a large extent, moved the impetus of many of these advertisements from illness to health. Two factors influenced alcohol advertising: the first being Prohibition Referenda which saw the emergence of advertising focused on placing alcohol in the household medicine chest. This highlighted the use of alcohol as a commodity commonly used in the home for medical and other emergencies and these advertisements informed readers of what could be lost if prohibition were passed. The second, and most significant change came about with the Medical Advertisements Act 1942 when any mention of cure or relief became unlawful.</p>

Cheers! Selling Health and Happiness: Advertising Alcohol in New Zealand, c.1900-1945.

<p>Abstract At the turn of the 20th century New Zealand’s newspapers were filled with advertising material offering information on a wide variety of products. Among these advertisements were those for alcohol, a commodity which the advertisements claimed to have multiple benefits, including those of a restorative and curative nature. This thesis will examine how two product groups, alcoholic beverages claiming medicinal value, and patent medicines containing alcohol, were advertised in selected New Zealand newspapers and magazines during the years 1900-1945. The advertising of these two groups was, in many ways, similar. Both used evocative text and images, with the images changing from drawn illustrations to photographs, and both targeted groups, linking these to specific drinks. For example, tonic wine advertising was aimed at women suffering from psychological distress, while beer and spirit advertisements targeted men and sporting codes, and patent medicine advertisements were designed to attract mothers and those suffering from respiratory illnesses. While both alcohol and patent medicines were subject to legislation this was not always effective. The Quackery Act 1908, which should have impacted on both alcohol and patent medicine advertising had no effect on either group. Patent medicine advertisers however, responded to the Physical Welfare Recreation Act 1937, and the Social Welfare Act 1938 with images of active, healthy children. The Medical Advertisements Act 1942 impacted immediately on alcohol advertising. but was not as successful with patent medicines. Both groups had significant changes affecting their advertising. For example, patent medicine advertising was dramatically altered by the discovery of vitamins. This, to a large extent, moved the impetus of many of these advertisements from illness to health. Two factors influenced alcohol advertising: the first being Prohibition Referenda which saw the emergence of advertising focused on placing alcohol in the household medicine chest. This highlighted the use of alcohol as a commodity commonly used in the home for medical and other emergencies and these advertisements informed readers of what could be lost if prohibition were passed. The second, and most significant change came about with the Medical Advertisements Act 1942 when any mention of cure or relief became unlawful.</p>

Efficacy and Safety of the Chinese Patent Medicine Yuquan Pill on Type 2 Diabetes Mellitus Patients: A Systematic Review and Meta-Analysis

Background. Yuquan Pill (YQP), a Chinese patent medicine for the treatment of diabetes, is widely used in the treatment of diabetes and its complications in China. However, the efficacy of YQP on type 2 diabetes mellitus (T2DM) has not been completely assessed. The aim of this study is to evaluate the efficacy and safety of YQP in the treatment of T2DM. Materials and Methods. We systematically searched 9 databases for specific keywords from inception to Oct 2021. We included randomized controlled trials (RCTs) involving YQP in the treatment of T2DM without language limitation. The study conformed to the Cochrane Handbook and Review Manager software was used for data analysis. The weighted mean differences (WMDs) and 95% confidence intervals (CIs) were used to measure treatment effects. Results. The final analysis included 10 publications. Analysis showed that the combination of YQP and conventional treatment was more effective than conventional treatment alone with regard to the levels of fasting blood glucose (WMD = −0.83; 95% CI [−1.01,−0.66]; p < 0.00001 ), two-hour postprandial glucose (WMD = −1.40; 95% CI [−1.49,−1.31]; p < 0.00001 ), glycosylated hemoglobin (WMD = −0.87; 95% CI [−1.26, −0.49]; p < 0.00001 ), total cholesterol (WMD = −0.50; 95% CI [−0.61, −0.39]; p < 0.00001 ), c-reactive protein (WMD = −0.58; 95%CI [−0.88, −0.28]; p = 0.0002 ), and overall effective rate (RR = 1.21; 95% CI [1.12, 1.31]; p < 0.00001 ). Conclusion. Evidence suggested that YQP might improve glucose and lipid metabolism and inflammation in patients with T2DM. Serious adverse events were not reported. The quality of the evidence analyzed was low and therefore our results should be interpreted with caution. More high-quality RCTs are now needed to verify these findings.

Angus Fletcher’s Other Literary Darwinism

Angus Fletcher pitches his book to general readers. Though it consists of literary criticism, it is designed as a psychological self-help manual-literature as therapy. Fletcher's thera­peutic program is presented as an alternative to the kind of literary Darwinism that iden­tifies human nature as the basis for literature. He acknowledges the existence of human nature but aims at transcending it by promoting an Aquarian ethos of harmony and un­derstanding. He has some gifts of style, but the dominant voice in his stylistic blend is that of the shill hawking a patent medicine. He presents himself as a modern sage who reveals an ancient but long-lost technique for using literature to boost happiness and well-being. Each of his 25 chapters identifies a distinct literary technique and uses popularized neuro­science to describe its supposedly beneficial psychological effects. Fletcher’s chains of rea­soning are habitually tenuous, and his exposition is littered with factual errors that betray ignorance of the books, genres, and periods he discusses. Despite its shortcomings, Fletch­er’s book has received encomiums from prestigious researchers, including the psychologist Martin Seligman and the neuroscientist Antonio Damasio. In evaluating Fletcher’s rhetor­ical style, analytic categories, Aquarian ethos, historical self-narrative, pattern of reasoning, and literary scholarship, this review essay reaches a more negative judgment about the value of his book. As an alternative to Fletcher’s book, I recommend a few evolutionary literary works for general readers.