Development and Validity of Questionnaire for Healthy Adult Human Participants of Early Phase Bioequivalence Pharmacokinetic Endpoint Study

Participation of humans in clinical research is always remained questionable. Hence evaluation of such doubt helps to conclude the perception about such participation. This research presents the process for development and validation of questionnaire for Healthy Adult Human Participants of Early Phase Bioequivalence Pharmacokinetic Endpoint Study. For development of questionnaire, literature search, experts’ discussion and authors’ experience was used for domain identification and its segregation for different variables. For validity of questionnaire, face validity and content validity was performed. Modification was done based on response from experts during non-quantitative face validity. % of overall agreement was 94.55 for question asked in face validity. While, Content Validity Ratio and Content Validity Index was calculated using the process mentioned by Lawshe and Lynn respectively. Initially 83 items were identified but based on validation 84 items were finalized after removal of three and addition of four questions. Deleted three items had Content Validity Ratio of 0.00, 0.67 and 0.67 and which were below accepted level of 0.99. While, I-CVI was observed from range of 0.83 to 1.00 and S-CVI values were above acceptable level of 0.90 for S-CVI (S-CVI/ Ave) and 0.80 for S-CVI (S-CVI/UA) for whole questionnaire and each part.

MEASURE OF GOVERNMENT EMPLOYEES’ CAREER INTENTIONS: DESIGN AND VALIDATION OF QUESTIONNAIRE

Career intentions of employees reflect the organizational effectiveness and dynamism within the organization. To address the gap on the measure of career intentions, a questionnaire was developed and psychometrically tested. The items were generated based on the literature and interview with HR Heads and officers from the target organization. The content validity was established through the review of experts. While the internal reliability, construct and convergent validity was assessed using the confirmatory factor analysis. The statistical analysis showed that the developed questionnaire was found to be valid and reliable and may be utilized to gather and conduct future studies on career development. <p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0892/a.php" alt="Hit counter" /></p>

Development and Validation of Questionnaire Measuring Registered Nurses' Competencies, Beliefs, Facilitators, Barriers, and Implementation of Evidence-Based Practice (EBP-CBFRI)

BackgroundConsideration needs to be given to a variety of factors that influence the implementation of evidence-based nursing practice (EBNP).AimThis study aimed to develop and validate a questionnaire that measures registered nurses' competencies, beliefs, facilitators, barriers, and implementation of EBNP.MethodsMethodological cross-sectional study in which 612 registered nurses were selected by convenient sampling. A panel of six experts evaluated the content validity of the first draft of the EBPCBFRI questionnaire. The final questionnaire was made up of 55 items. Reliability was determined by means of internal consistency. Construct, convergent, discriminant, and predictive validity was assessed.ResultsThe questionnaire has proven acceptable reliability and validity when used with registered nurses. The scale-level content validity index was .92. Cronbach's α coefficient for the total questionnaire was .87. Exploratory factor analysis supported five significant factors that explained 64.8% of the variance.

Development and Psychometric Attributes of a Theory-Based Physical Activity Assessment Questionnaire for the Pregnant Women (PA2Q-PW)

Background This study's goal was to design and validate questionnaires for using to distinguish PEN-3 cultural model determinant factors of exercise in pregnant women. A questionnaire of physical activity theory-based was performed in 400 pregnant women with the first pregnancy. The validation of questionnaire design was used to develop the measures, including validity, reliability, and factor analysis by correlating scores to be an exercise of pregnant women during pregnancy. MethodsThe perception scale contained two factors: Knowledge and attitudes The Nurtures scale contained one element: Support was sought. The Enabling level included one element: barriers. Coefficients of reliability ranged from within 0.99. Among the four scores, significant correlations were achieved in this study. Four scales to measure PEN-3 cultural model determinants factors of being active during pregnancy were reformed for utilization with country, mostly Tehran-Iran, pregnant women, and shown to be validity and reliability. ResultsFactor analysis resulted in interpretable subclass that may be used as variables. These preliminary results provide support; for using the scales to measure the influences on pregnant women's physical activity. ConclusionsThe Physical Activity Questionnaire for pregnant women Patients (PA2Q-PW) is the first instrument that uses the PEN-3 cultural model within its constructs. The results indicated that PA2Q-PW is a valid and reliable instrument for assessing physical activity perceptions and is now existing and can be used in future studies.