Emerging Internet of Things driven carbon nanotubes-based devices

Carbon nanotubes (CNTs) have attracted great attentions in the field of electronics, sensors, healthcare, and energy conversion. Such emerging applications have driven the carbon nanotube research in a rapid fashion. Indeed, the structure control over CNTs has inspired an intensive research vortex due to the high promises in electronic and optical device applications. Here, this in-depth review is anticipated to provide insights into the controllable synthesis and applications of high-quality CNTs. First, the general synthesis and post-purification of CNTs are briefly discussed. Then, the state-of-the-art electronic device applications are discussed, including field-effect transistors, gas sensors, DNA biosensors, and pressure gauges. Besides, the optical sensors are delivered based on the photoluminescence. In addition, energy applications of CNTs are discussed such as thermoelectric energy generators. Eventually, future opportunities are proposed for the Internet of Things (IoT) oriented sensors, data processing, and artificial intelligence.

Strategies for the preparation of non-amplified and amplified genomic dengue gene samples for electrochemical DNA biosensing applications

The application of electrochemical DNA biosensors in real genomic sample detection is challenging due to the existence of complex structures and low genomic concentrations, resulting in inconsistent and low current signals.

Construction of Photoelectrochemical DNA Biosensors Based on TiO2@Carbon Dots@Black Phosphorous Quantum Dots

In this work, carbon dots (CDs) and black phosphorus quantum dots (BPQDs) were used to decorate titanium dioxide to enhance the photoelectrochemical (PEC) properties of the nanocomposites (TiO2@CDs@BPQDs), and the modified nanocomposites were used to sensitively detect DNA. We used the hydrothermal method and citric acid as a raw material to prepare CDs with good dispersion and strong fluorescence properties. BPQDs with a uniform particle size were prepared from black phosphorus crystals. The nanocomposites were characterized by fluorescence spectroscopy, UV-Vis absorption spectroscopy, Fourier transform infrared spectroscopy (FTIR) and transmission electron microscopy (TEM). The preparation method of the working electrode was explored, the detection conditions were optimized, and the sensitive detection of target DNA was achieved. The results demonstrate that CDs and BPQDs with good optical properties were successfully prepared, and they were successfully combined with TiO2 to improve the PEC performance of TiO2@CDs@BPQDs. The TiO2-based PEC DNA detection method was constructed with a detection limit of 8.39 nM. The constructed detection method has many advantages, including good sensitivity, a wide detection range, and good specificity. This work provides a promising PEC strategy for the detection of other biomolecules.

Progress of Wearable and Flexible Electrochemical Biosensors With the Aid of Conductive Nanomaterials

Conductive nanomaterials have recently gained a lot of interest due to their excellent physical, chemical, and electrical properties, as well as their numerous nanoscale morphologies, which enable them to be fabricated into a wide range of modern chemical and biological sensors. This study focuses mainly on current applications based on conductive nanostructured materials. They are the key elements in preparing wearable electrochemical Biosensors, including electrochemical immunosensors and DNA biosensors. Conductive nanomaterials such as carbon (Carbon Nanotubes, Graphene), metals and conductive polymers, which provide a large effective surface area, fast electron transfer rate and high electrical conductivity, are summarized in detail. Conductive polymer nanocomposites in combination with carbon and metal nanoparticles have also been addressed to increase sensor performance. In conclusion, a section on current challenges and opportunities in this growing field is forecasted at the end.

Construction of DNA Biosensors for Mercury (II) Ion Detection Based on Enzyme-Driven Signal Amplification Strategy

Mercury ion (Hg2+) is a well-known toxic heavy metal ion. It is harmful for human health even at low concentrations in the environment. Therefore, it is very important to measure the level of Hg2+. Many methods, reviewed in several papers, have been established on DNA biosensors for detecting Hg2+. However, few reviews on the strategy of enzyme-driven signal amplification have been reported. In this paper, we reviewed this topic by dividing the enzymes into nucleases and DNAzymes according to their chemical nature. Initially, we introduce the nucleases including Exo III, Exo I, Nickase, DSN, and DNase I. In this section, the Exo III-driven signal amplification strategy was described in detail. Because Hg2+ can help ssDNA fold into dsDNA by T-Hg-T, and the substrate of Exo III is dsDNA, Exo III can be used to design Hg2+ biosensor very flexibly. Then, the DNAzyme-assisted signal amplification strategies were reviewed in three categories, including UO22+-specific DNAzymes, Cu2+-specific DNAzymes and Mg2+-specific DNAzymes. In this section, the Mg2+-specific DNAzyme was introduced in detail, because this DNAzyme has highly catalytic activity, and Mg2+ is very common ion which is not harmful to the environment. Finally, the challenges and future perspectives were discussed.