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2022 ◽  
Vol 1048 ◽  
pp. 279-290
Author(s):  
Paolo Minetola ◽  
Vinicius de Freitas Pacheco ◽  
Marcelo Massarani ◽  
Flaviana Calignano ◽  
Giovanni Marchiandi

In recent years, the diffusion of additive manufacturing (AM) or 3D printing (3DP) techniques for polymers have been boosted by the expiration of earlier patents from the last century and the development of low-cost machines. Since these technologies become more widespread, there is a need to assess the capability and accuracy of low-cost machines in terms of dimensional and geometric tolerance. To this aim, this work proposes an innovative reference part for benchmarking layerwise processes that involve the curing of photopolymers. The geometry of the part is conceived to include several classical shapes that are easily measurable for defining the part accuracy in terms of ISO IT grades and GD&T values. Two replicas of the reference part were fabricated by stereolithography (SLA) and digital light processing (DLP) using two machines and related proprietary materials by Sharebot Company. The replicas were printed with a layer thickness of 50 μm for the DLP process and 100 μm for the SLA one. The results of dimensional measurements of the replicas, that were carried out using a Coordinate Measuring Machine (CMM), show that the geometric accuracy of the time-consuming DLP process is slightly better than that of stereolithography.


Author(s):  
Mingxing Chen ◽  
Simeng Qin ◽  
Sitao Yang ◽  
Huaping Chen ◽  
Liuyi Lu ◽  
...  

Summary Background. The values of biomarkers play a central role in routine clinical decision-making. Whereas, the performances of different automated chemical analyzers remain unclear. To determine the performances of different platforms, we evaluated the capability between Roche Cobas 8000 and Mindray BS2000M.  Methods. A total of 1869 remaining serum samples were collected. CK, LDH-1, RBP, Cys-c, IgA, IgM and IgG were assessed by using paired-t test, Passing-Bablok regression analysis and Bland Altman analysis according to CLSI EP5-A3. Results. There were significant in average bias of all items between two machines (P < 0.001). Due to the 95% confidence interval of intercept A included 0, CK, LDH-1, Cys-c and IgG were not show systemic error in Passing-Bablok regression analysis. Except for IgA, the r values and correlation coefficient of all items were higher than 0.91, which showed that the correlation and consistency is good. The Bland-Altman analysis showed that two instruments had more than 95% of the points apart from CK, LDH-1, and IgA. Conclusions. It can be considered that the two instruments have good correlation and consistency in CK, LDH-1, RBP, Cys-c, IgM and IgG, and the two instruments are interchangeable and can replace each other.


2021 ◽  
Vol 13 (2) ◽  
pp. 62-79
Author(s):  
Юлия Васильевна Чиркова ◽  
Julia Chirkova

The Machine Load Balancing Game with linear externalities is considered. A set of jobs is to be assigned to a set of machines with different latencies depending on their own loads and also loads on other machines. Jobs choose machines to minimize their own latencies. The social cost of a schedule is the maximum delay among all machines, i.e. {\it makespan. For the case of two machines in this model an Nash equilibrium existence is proven and of the expression for the Price of Anarchy is obtained.


mBio ◽  
2021 ◽  
Author(s):  
Patricia L. Foster ◽  
Brittany A. Niccum ◽  
Heewook Lee

Because DNA replication and transcription occur on the same DNA template, encounters between the two machines occur frequently. When these encounters are head-to-head, genomic disruption can occur.


2021 ◽  
Vol 16 ◽  
Author(s):  
Umberto Vincenzi

Often, in supporting patients suffering from severe respiratory diseases with mechanical ventilation, obstacles are encountered due to pulmonary and/or thoracic alterations, reductions in the ventilable lung parenchyma, increases in airway resistance, alterations in thoraco-pulmonary compliance, advanced age of the subjects. All this involves difficulties in finding the right ventilation parameters and an adequate driving pressure to guarantee sufficient ventilation. Therefrom, new mechanical ventilation techniques were sought that could help overcome the aforementioned obstacles. A new mode of mechanical ventilation is being presented, i.e., a Positive + Negative Synchronized Ventilation (PNSV), characterized by the association and integration of two pulmonary ventilators; one acting inside the chest with positive pressures and one externally with negative pressure. The peculiarity of this combination is the complete synchronization, which takes place with specific electronic modifications. The PNSV can be applied both in a completely non-invasive and invasive way and, therefore, be used both in acute care wards and in ICU. The most relevant effect found, due to the compensation of opposing pressures acting on the chest, is that, during the entire inspiratory act created by the ventilators, the pressure at the alveolar level is equal to zero even if adding together the two ventilators’ pressures; thus, the transpulmonary pressure is doubled. The application of this pressure for 1 hour on elderly patients suffering from severe acute respiratory failure, resulted in a significant improvement in blood gas analytical and clinical parameters without any side effects. An increased pulmonary recruitment, including posterior lung areas, and a reduction in spontaneous ventilatory rate have also been demonstrated with PNSV. This also paves the way to the search for the best ventilatory treatment in critically ill or ARDS patients. The compensation of intrathoracic pressures should also lead, although not yet proven, to an improvement in venous return, systolic and cardiac output. In the analysis of the study in which this method was applied, the total transpulmonary pressure delivered was the sum of the individual pressures applied by the two ventilators. However, this does not exclude the possibility of reducing the pressures of the two machines to modulate a lower but balanced total transpulmonary pressure within the chest.


2021 ◽  
Vol 15 (5) ◽  
pp. 661-668
Author(s):  
Ryo Yonemoto ◽  
◽  
Haruhiko Suwa

Manufacturing systems are affected by uncertainties, such as machine failure or tool breakage, which result in system downtime and productivity deterioration. In machining processes, system downtime must be reduces. This study aims to establish an automated scheduling technique that flexibly responds to unforeseen events, such as machine failure, based on adaptive operations of the handling manipulator instead of an operation schedule for the machine tools. We propose an “adaptive manipulation” procedure for establishing a reactive revision policy. The reactive revision policy modifies a portion of the manipulator operation sequence, followed by the machine operation sequence. We conduct a physical scheduling simulation on a material-handling manipulator system imitating a job-shop manufacturing system. Through simulations involving machine breakdown scenarios, the applicability of the reactive revision policy based on adaptive manipulation is demonstrated.


2021 ◽  
Vol 19 ◽  
pp. 282-286
Author(s):  
M.B.S. Pinto ◽  
◽  
G.P. Viajante ◽  
E.N. Chaves ◽  
M.A.A. Freitas ◽  
...  

This paper presents a comparative study between the Switched Reluctance Machine (SRM) 8x6 and 6x4 operating as a motor with both 60kW of power. The computer simulation was performed in Matlab™ / Simulink® environment and allowed the machine behavior under various operating conditions to be verified. This work made it possible to evaluate: phase voltage and current, speed, torque and efficiency. Comparative results between the two machines will be presented and discussed.


2021 ◽  
Vol 53 (4) ◽  
pp. 673-695
Author(s):  
Colin Danby

James Meade played an important role in the 1951 development of the “Mark II” Newlyn-Phillips machine, including making it fit for connection to a mirror-image machine so that policy interactions between two countries could be demonstrated. In 1952 Phillips built, for Meade, a “foreign exchange market” to link two machines. This article reconstructs the linking device from archival evidence, and places the resulting two- country model in the context of Meade’s thought.


Author(s):  
Edwin M. Graycochea Jr. ◽  
Rennier S. Rodriguez ◽  
Frederick Ray I. Gomez

Theta rotation on die during diebond process is one of the critical machine responses especially for land grid array (LGA) device with tight tolerances requirement. The paper focuses on the die theta rotation tolerance capability with critical design for LGA device evaluated on two different diebond machine platforms. The evaluation was narrowed down into two main diebond machines with the objective of attaining the best performance in terms of die theta rotation tolerance capability. The study used a side-by-side comparison analysis in terms of theta rotation on the two machines and presented the effect of machine selection on the theta rotation response. Theta rotation was monitored and both machines satisfied the specification of 1 degree of maximum rotation, though diebond Machine 1 was able to produce a more stable diebonding with only around less than 0.15 degree of theta rotation variation. For future works, the selected diebond machine could be used for devices with critical requirement.


Author(s):  
Shaopeng Wang ◽  
Jinguang Ma ◽  
Chengcheng Liu ◽  
Youhua Wang ◽  
Gang Lei ◽  
...  

This paper proposes a novel permanent magnet assisted synchronous reluctance (PMAREL) machine, the main structure of this machine is quite similar to that of traditional PMAREL machine, and the main difference is that the grain-oriented silicon steel is used to replace some part of the stator teeth. The rolling direction of the grain-oriented silicon steel is along the radial direction of the machine, thus the advantage of higher permeability and higher kneel point in this material can be used to release the flux saturation problem of the traditional non-grain-oriented steel used in the PMAREL machine when the applied current density is high. Firstly, the structure of both proposed novel and traditional PMAREL machines are optimized and the design parameters are determined. Secondly the electromagnetic and mechanical performance are compared in these two machines which includes the demagnetization analysis, mechanical stress analysis when the rotor at the maximum speed, torque ability, efficiency by using the finite element method (FEM). It can be seen that the problem of stator teeth saturation in the novel PMAREL has been alleviated, and compared with the traditional PMAREL machine, the novel PMAREL has higher efficiency, wider speed range and 7% higher torque ability.


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