Abstract
Background: Expanded local resection is suitable for recurrent breast cancer patients who have isolated local lesion and have not metastasized. The extend of chest wall resection must be overall radical resection of the tumors diagnosed by pathology. However, surgery often leads to huge defects, even full-thickness defects, and these defects are difficult to repair. Here, we reported our experience in chest wall resection and reconstruction of patients with locally recurrent breast cancer, and also did a comprehensive literature review.Case Presentation: We report five cases with locally recurrent breast cancer, followed by chest wall reconstruction with a pedicled rectus abdominis musculocutaneous flap or a pedicled latissimus dorsi musculocutaneous flap and, if necessary, a piece of titanium mesh. Chest wall resection and reconstruction were successfully achieved in all 5 patients. No complication and recurrence were observed, except one patient died of late lymphatic metastasis. Other patients reported good quality of life.Conclusion: For locally recurrent breast cancer, complete tumor resection is essential and ensures no recurrence. Appropriate material and the blood-rich flap or myocutaneous flap should be used to reconstruct the chest wall defect as an effective treatment for surgical procedure.