pullulan acetate
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2018 ◽  
Vol Volume 13 ◽  
pp. 4073-4082 ◽  
Author(s):  
Hongbo Tang ◽  
Ziwen Jiang ◽  
Haibo He ◽  
Xiaoqin Li ◽  
Haipeng Hu ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Kwang Sik Yu ◽  
Jun Young Oh ◽  
Min Cheol Kim ◽  
Seong Hee Kang ◽  
Nam Seob Lee ◽  
...  

The neuroprotective effects of the ursodeoxycholic acid- (UDCA-) loaded pullulan acetate (PA) (UDCA-PA) nanospheres stabilized by poly(vinyl alcohol) (PVA) were identified by in vitro study. The UDCA-PA nanospheres were constructed by nanoemulsion process. The UDCA-PA nanospheres were analyzed using Fourier transform-infrared spectroscopy (FT-IR) and transmission electron microscopy (TEM). Then, the UDCA-PA nanospheres were used to treat PC-12 neuronal cells, which were formerly triggered by glutamate-induced excitotoxicity. As a result, the cells treated with the UDCA-PA nanospheres showed higher survival rate against glutamate-induced excitotoxicity. Furthermore, the UDCA-PA nanospheres decreased immunoreactivity of Annexin V, a membrane marker for apoptotic cells, in PC-12 with glutamate-induced injury. Particularly, the UDCA-PA nanospheres decreased the level of apoptosis-related proteins such as caspase-3. Taken together, the UDCA-PA nanospheres increased neuroprotective effects against glutamate-induced neuronal damage via inhibition of apoptosis at low concentration.


2017 ◽  
Vol 13 (9) ◽  
pp. 1134-1146 ◽  
Author(s):  
Hongli Chen ◽  
Xiangjuan Wei ◽  
Jingwen Qin ◽  
Hongyang Chen ◽  
Zijing Shen ◽  
...  

2016 ◽  
Vol 8 (11) ◽  
pp. 2029-2036 ◽  
Author(s):  
Hongli Chen ◽  
Yajing Jia ◽  
Wenbin Nan ◽  
Hongbo Tang ◽  
Zhimin Zhou ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (7) ◽  
pp. 5599-5610 ◽  
Author(s):  
Moorthy Ganeshkumar ◽  
Thangavel Ponrasu ◽  
Muthaiya Kannappan Subamekala ◽  
Murthy Janani ◽  
Lonchin Suguna
Keyword(s):  

Curcumin loaded nanoparticles protect liver from damage induced by DEN.


2015 ◽  
Vol 10 ◽  
pp. 2-9 ◽  
Author(s):  
D. Saranya ◽  
Reshma Rajan ◽  
V. Suganthan ◽  
A. Murugeswari ◽  
N. Arunai Nambi Raj

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