Dynamics of Freezing and Warming of Soft Tissues with Short-Term Eff ect on Skin with Cryoapplicator

The paper presents the analysis of possibilities and limitations of using the thermal imaging to monitor the dynamics of temperature field caused by a short-term cryoablation of skin. It is shown that the method allows to remote and intraoperative control the dynamics of the freezing zone diameter as well as to estimate the current diameter of primary cryonecrosis zone. The diameter of primary cryonecrosis zone for this type of tissues reaches 13 mm, which makes it possible to destroy small morbid growth by low temperatures even with a short-term (30 s) croexposure. The using of this method to monitor the process of natural warming has shown the presence of long quasi-stable stage in dynamics of the freezing zone diameter with a slight change in the temperature field. This fact is likely due to structural changes in frozen tissues.

A COMPARATIVE CLINICAL STUDY OF KADALI KSHARA AND APAMARGA KSHARA IN THE MANAGEMENT OF CHARMAKEELA (WARTS)

Charmakeela is one of the Kshudraroga mentioned by Acharya Sushrutha and Vagbhata. Vyanavata combines with Kapha produces piles on the exterior of the skin resembling a nail which is static or immov-able and rough is called as Charmakeela. Based upon the clinical features explained in Ayurveda, Char-makeela can be correlated with that of warts. Objective: The present study was to evaluate the comparative effect of Kadalikshara and Apamargakshara in the management of Charmakeela. Methods: 40 patients were randomly selected and divided into 2 groups. Results: The statistical Analysis the study reveals there is no significant difference between found statistically between Kadalikshara and Apamargakshara, so both KadaliKshara and ApamargaKshara are having same Qualitative Equanimity effect of treatment on the disease. Conclusion: As observed from the results the total removal of Charmakeela was possible in all cases and it proves the authenticity of the classical ayurvedic reference which state that Charmakeela can be removed by the application of Prathisarneeyakshara. In this study the action of the drugs KadaliKshara and ApamargaKshara on the removal of Charmakeelais well established. The clearance may be faster in case of thin lesions and it may be slower in case of thicker lesion because of variations in the thickness of morbid growth in all patient, removal of lesion of Charmakeela there may be slight blackish brown discol-ouration occurs at the site of lesion was observed. This may be considered as Samyakdagdhalaxanas of Kshara Karma which will disappear gradually.

Case Report: Erythroblastosis and Leukemia

The authors report the case of a man, 29 years old, who presented initially a marked erythroblastosis (10,000 to 150,000 erythroblasts per mm.3) in the peripheral blood. Originally, a great hyperplasia of the red system in the bone marrow existed. Gradually this morbid growth of the "red" system was superseded by a proliferation of myeloblasts. After an illness of about one year’s duration the patient died in a myeloblastic "crisis." It is pointed out that owing to prolongation of life in this case through repeated blood transfusions and penicillin, the opportunity was presented to observe different hematologic syndromes in the same patient. With the common use of potent therapeutic procedures this situtation is now increasingly present. It may lead to the ultimate recognition that different hematologic syndromes are in reality different manifestations of the same disease. The various diseases in which an erythroblastosis may occur are discussed.

A theory of the action of rays on growing cells

The recent accessions to our knowledge of the nature of γ - and X-rays bring the treatment, by these rays, of malignant and morbid growths, into continuity with the treatment of lupus, etc., by the Finsen light or by other actinic radiation. The pathological effects of the shorter and more penetrating waves have been described by experienced observers as stimulative of the morbid growth when the administered radiation is feeble in intensity and as inhibitive of growth when the radiation is sufficiently intense. Here there is plainly an effect produced by the short waves upon the growing cell, and the question arises if from this and allied observations we cannot gain some insight into the nature of the activity which characterises the malignant and morbid cell.