Why, in some multi-level systems, does political competition preserve highly independent spheres of political life across the units and levels of a federation, while in other multi-level systems, political competition results in the emergence of a shared political space? This chapter argues that these patterns of independent or integrated politics in multi-level systems are shaped in important ways by the federal institutional structure, which shapes the incentives that parties and voters alike face. Surveying the literature that identifies how institutions impact party organization, party systems, and electoral behaviour, this chapter sets out a two-stage causal process whereby institutions shape aspects of integrated politics and aspects of integrated politics reinforce each other.