This chapter presents the methodological and conceptual approach, which informed the research design for the study. It is pertinent to reiterate here that the design of this study sought to discern the positive psychological forces that shape subjective wellbeing of informal caregivers. This desire prompted the adoption of a mixed methods research. The rationale for this methodological preference is presented. In addition, advantages of mixed methods approach are elaborated upon. Furthermore, other issues are addressed, including sample size, instrumentation, and research procedures. This chapter also explains, with much detail, the parameters and boundary conditions that constituted the guiding assumptions, limitations, as well as delimitations of the study. It should be noted that the chapter also explains the essential approach to data analysis.