In the current phase of global geopolitical transition, Ukraine finds itself – now more than ever – dependent on the macro-dimension dynamics, on the global dynamics and on the fast-changing balance of power of the international chessboard. A less cohesive Euro-Atlantic front, the return of a classic Machtpolitik of both regional and international powers – such as Russia, Turkey and China – and the return of sovereign-nationalist approaches in various central-western states, stand out on the future of the Slavic country, augmenting risks and uncertainties. A country placed on the sound binary of a democratic path and going towards an approximation to the European Union, although marked by internal crises, risks for its state-territorial cohesion, and continuous hardships in the implementation of the age-old structural reforms so badly needed. The only certainty left, in this delicate phase of the international system transition and (the relative) weakening of the unipolar western-led order – seems, however, the continuation of the process of integration into the Euro-Atlantic structures.