The Tiworo River Watershed, which covers a total area of 29,047.82 ha, has been a resource for agricultural development for the local people of Muna, Indonesia. The information regarding the land suitability for annual crops in this watershed was, however, still very limited. A survey-based study was, therefore, conducted to evaluate the land suitability in the watershed for six annual crops (i.e. paddy-rice, corn, peanut, soybean, cassava, and tomato). The evaluation was based on Djaenuddin’s criteria, that was by matching the respective crop growth requirements against soil characteristics (e.g. soil pH, organic-C content, total-N, P2O5, K2O, CEC, base saturation, soil texture and drainage, rock outcrops, effective soil depth, and slope) and climate (e.g. rainfall, and air temperature and humidity). Soil characteristics were collected from 87 land units. A ten-year climate data series was gathered from the Betoambari weather station. The results of the evaluation showed that the land in the watershed fell into class S3 (marginally suitable) and class N (not suitable) for all the six crops evaluated, and no land units belonged to S1 (highly suitable) and S2 (moderately suitable). The main limiting factors found were low water and nutrient availability, and high erosion hazard.