Why do U.S. Attorneys leave office, and what do they do when they finish their tenure? Federal prosecutors serve at the pleasure of the president and can be dismissed using a president’s removal power. Analyzing data on U.S. Attorneys since the Reagan Administration, we demonstrate that, aside from a routine turnover of U.S. Attorney positions at the beginning of a new administration, presidents rarely fire U.S. Attorneys. When presidents remove chief federal prosecutors in the middle of their term, they typically pay great political costs to do so. We further follow these U.S. Attorneys’ careers—to Congress, the bench, and the governor’s mansion—after they leave office, illustrating that U.S. Attorney positions serve as a springboard for many ambitious politicians to seek higher office. In this way, presidential selections of federal prosecutors have long-lasting effects on American politics.