Sport as a practice and cognitive event is largely action-oriented: there is thought in action, even if it is not particularly conscious thought. Habits codified in the motor regions of the brain underlie action. Muscle memory is fundamental; it is a metaphor for the organization of action. Importantly, neurotransmitters such dopamine are tied to the organization of action, salience, cognition, and, perhaps, the prediction of events. Diverse regions of the brain (e.g., the amygdala) and neuropeptides (oxytocin) are linked to social contact and play-related behaviors, and these same regions are crucial to a broad-based assessment of social context and meaning.