Cell Transplantation for Neurological Disorders: Toward Reconstruction of the Human Nervous System

1999 ◽  
Vol 56 (5) ◽  
pp. 631
Author(s):  
Ben Zion Roitberg
Keyword(s):  
Nervous System ◽  
Cell Transplantation ◽  
Neurological Disorders ◽  
Human Nervous System

Neurological disorders associated with Covid-19 (literature review)

2020 ◽  
Vol 21 (4) ◽  
pp. 140-144
Author(s):  
M. A. Ahmet’yanov ◽  
◽  
O. A. Kicherova ◽  
L. I. Reikhert ◽  
M. V. Deeva ◽  
...  
Keyword(s):  
Nervous System ◽  
Literature Review ◽  
Healthcare System ◽  
Neurological Disorders ◽  
Neurological Complications ◽  
Pathological Conditions ◽  
Prevention And Treatment ◽  
Coronavirus Infection ◽  
Human Nervous System

The pandemic of the new SARS-CoV2, that started at the beginning of 2020, caused a catastrophic increase in morbidity and mortality in early 2020 and posed a number of challenges for healthcare system. Primarily, this concerns the study of the effect on different organs and systems, that new virus can exhibit. This knowledge further can serve as a key to the development of effective methods for the prevention and treatment of COVID-19 associated pathological conditions. The objectives of this review include the analysis of neurological complications caused by the new coronavirus infection and the determination of the possible mechanisms of the virus’s effect on the human nervous system.

scholarly journals Aconitine Neurotoxicity According to Administration Methods

2021 ◽  
Vol 10 (10) ◽  
pp. 2149
Author(s):  
Ji Yeon Chung ◽  
Seung Jae Lee ◽  
Hyuck Jin Lee ◽  
Jeong Bin Bong ◽  
Chan-Hyuk Lee ◽  
...  
Keyword(s):  
Nervous System ◽  
Pain Control ◽  
Associated Factors ◽  
Clinical Characteristics ◽  
Processing Method ◽  
Neurological Symptoms ◽  
Administration Method ◽  
Accompanying Symptoms ◽  
Administration Methods ◽  
Human Nervous System

We evaluated the toxic effects of aconitine on the human nervous system and its associated factors, and the general clinical characteristics of patients who visited the emergency room due to aconitine intoxication between 2008 and 2017. We also analyzed the differences related to aconitine processing and administration methods (oral pill, boiled in water, and alcohol-soaked), and the clinical characteristics of consciousness deterioration and neurological symptoms. Of the 41 patients who visited the hospital due to aconitine intoxication, 23 (56.1%) were female, and most were older. Aconitine was mainly used for pain control (28 patients, 68.3%) and taken as oral pills (19 patients, 46%). The patients showed a single symptom or a combination of symptoms; neurological symptoms were the most common (21 patients). All patients who took aconitine after processing with alcohol showed neurological symptoms and a higher prevalence of consciousness deterioration. Neurological symptoms occurred most frequently in patients with aconitine intoxication. Although aconitine intoxication presents with various symptoms, its prognosis may vary with the processing method and prevalence of consciousness deterioration during the early stages. Therefore, the administration method and accompanying symptoms should be comprehensively investigated in patients who have taken aconitine to facilitate prompt and effective treatment and better prognoses.

scholarly journals Current Knowledge of Endolysosomal and Autophagy Defects in Hereditary Spastic Paraplegia

Cells ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1678
Author(s):  
Liriopé Toupenet Marchesi ◽  
Marion Leblanc ◽  
Giovanni Stevanin
Keyword(s):  
Nervous System ◽  
Motor Neurons ◽  
Neurological Disorders ◽  
Hereditary Spastic Paraplegia ◽  
Current Knowledge ◽  
Spastic Paraplegia ◽  
Functional Convergence ◽  
The Common ◽  
Hsp Genes

Hereditary spastic paraplegia (HSP) refers to a group of neurological disorders involving the degeneration of motor neurons. Due to their clinical and genetic heterogeneity, finding common effective therapeutics is difficult. Therefore, a better understanding of the common pathological mechanisms is necessary. The role of several HSP genes/proteins is linked to the endolysosomal and autophagic pathways, suggesting a functional convergence. Furthermore, impairment of these pathways is particularly interesting since it has been linked to other neurodegenerative diseases, which would suggest that the nervous system is particularly sensitive to the disruption of the endolysosomal and autophagic systems. In this review, we will summarize the involvement of HSP proteins in the endolysosomal and autophagic pathways in order to clarify their functioning and decipher some of the pathological mechanisms leading to HSP.

scholarly journals Meningitis Caused by Salmonella Newport in a Five-Year-Old Child

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Ana De Malet ◽  
Sheila Ingerto ◽  
Israel Gañán
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurological Disorders ◽  
Invasive Disease ◽  
Salmonella Typhi ◽  
Gram Negative ◽  
Negative Bacillus ◽  
Salmonella Newport ◽  
Gram Negative Bacillus ◽  
The Central Nervous System

Salmonella Newport is a Gram-negative bacillus belonging to the Enterobacteria family and the nontyphi Salmonella (NTS), usually related to gastroenteritis. Main difference between NTS and Salmonella typhi is that the last one evolves to an invasive disease easier than NTS. These can progress to bacteremias in around 5% of cases and secondary focuses can appear occasionally, as in meningitis. An infection of the central nervous system is uncommon, considering its incidence in 0.6–8% of the cases; most of them are described in developing countries and mainly in childhood, especially neonates. Bacterial meningitis by NTS mostly affects immunosuppressed people in Europe. Prognosis is adverse, with a 50% mortality rate, mainly due to complications of infection: hydrocephalus, ventriculitis, abscesses, subdural empyema, or stroke. Choice antibiotic treatments are cefotaxime, ceftriaxone, or ceftazidime. The aim of this paper is to present a case of meningitis caused by Salmonella Newport diagnosed in a five-year-old girl living in a rural area of the province of Ourense (Spain), with favorable evolution and without neurological disorders.

An X-ray diffraction comparison of myelins from the human nervous system

1978 ◽  
Vol 177 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Ronald J. Chandross ◽  
Richard S. Bear ◽  
Royce L. Montgomery
Keyword(s):  
Nervous System ◽  
X Ray Diffraction ◽  
X Ray ◽  
Human Nervous System
Sign in / Sign up

Export Citation Format

Share Document