scholarly journals Inflammatory Arthritis and the Effect of Physical Activity on Quality of Life and Self‐reported Function: A Systematic Review and Meta‐analysis – The ENHANCE Study

2021 ◽  
Author(s):  
Mathilda Björk ◽  
Elena Dragioti ◽  
Helene Alexandersson ◽  
Bente Appel Esbensen ◽  
Carina Boström ◽  
...  
BMJ Open ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. e031374 ◽  
Author(s):  
Esther Ubago-Guisado ◽  
Luis Gracia-Marco ◽  
Iván Cavero-Redondo ◽  
Vicente Martinez-Vizcaino ◽  
Blanca Notario-Pacheco ◽  
...  

IntroductionCancer (and survival) is known to affect the quality of life. Strategies as physical activity and exercise during and after cancer may improve health-related qualify of life (HRQOL) outcomes and are, therefore, of clinical and public health importance. To the best of our knowledge, comparative evidence of the effect of the different types of exercise on improving HRQOL in cancer patients has not been synthesised thus far. We aim to conduct a systematic review and network meta-analysis in order to synthesise all available evidence regarding the effect of different types of exercise interventions on HRQOL during and after cancer treatment.Methods and analysisMEDLINE (via PubMed), Web of Science, Embase, The Cochrane Library and SPORTDiscus will be searched from inception to December 2018 for relevant randomised controlled trials (RCTs) and non-RCTs. Studies assessing physical activity and exercise interventions in cancer patients (during treatment) and survivors (after treatment) will be selected. Two independent reviewers will identify eligible studies. After quality appraisal and data extraction, we will conduct meta-analyses for outcomes of interest, including data from mental and physical dimensions of cancer-specific and/or generic HRQOL questionnaires. Risk of bias assessments will be completed using the Quality Assessment Tool for Quantitative Studies. Study heterogeneity will be measured by the I2 statistic. Bayesian (and traditional approach) network meta-analysis will be performed when possible to determine the comparative effect of the different physical activity or exercise interventions.Ethics and disseminationThis systematic review and network meta-analysis will synthesise evidence on the effect of different types of exercise interventions on HRQOL during and after cancer treatment. The results will be disseminated by publication in a peer-reviewed journal and through scientific conferences and symposia. Ethical approval will not be required because the data used for this work will be exclusively extracted from published studies.PROSPERO registration numberCRD42019125028.


2014 ◽  
Vol 23 (5) ◽  
pp. 1237-1250 ◽  
Author(s):  
S. J. Otto ◽  
I. J. Korfage ◽  
S. Polinder ◽  
A. van der Heide ◽  
E. de Vries ◽  
...  

Author(s):  
Lívia Carvalho Sette Abrantes ◽  
Núbia de Souza de Morais ◽  
Vivian Siqueira Santos Gonçalves ◽  
Sarah Aparecida Vieira Ribeiro ◽  
Catarina Maria Nogueira de Oliveira Sediyama ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Merete Kolberg Tennfjord ◽  
Rakel Gabrielsen ◽  
Tina Tellum

Abstract Background Endometriosis is a common benign gynecological disease that has the potential to debilitate due to pain and reduced quality of life. Treatment modalities such as hormones and surgery have limitations and do not treat all dimensions of the problems caused by endometriosis, and physical activity (PA) and exercise have been suggested as alternative treatments. Aim of this study was to perform a systematic review and meta-analysis to assess the effect of PA and exercise on endometriosis-associated symptoms. Methods Eleven databases were searched systematically. Study selection, quality assessment, and data extraction were carried out by two independent researchers in accordance with PRISMA guidelines. Eligibility criteria were women with diagnosed endometriosis receiving an intervention (PA and/or exercise). The primary outcome was pain intensity, but all outcomes were accepted. Results This study screened 1045 citations for eligibility. Four interventional studies were identified, of which one showed fatal design flaws and so was excluded. Three studies, two randomized controlled trials (RCT) and one pre-post study with no control group, involving 109 patients were included in a descriptive synthesis. The interventions included flexibility and strength training, cardiovascular fitness, and yoga, and were performed from one to four times per week for a total duration of 8–24 weeks, with or without supervision. Only one study found improvements in pain intensity. One study showed decreases in stress levels. Due to the heterogeneity of the study outcomes and measures, as well as confounding factors, a quantitative meta-analysis could not be performed. Conclusion The effect of PA and exercise as treatments for endometrioses-associated symptoms could not be determined due to significant limitations of the included studies. Future research should be based on RCTs of high methodological quality, measuring and reporting relevant core outcomes such as pain, improvements in symptoms and quality of life, and acceptability and satisfaction from the perspectives of patients. Furthermore, these outcomes need to be measured using reliable and validated tools. Trial registration number CRD42021233138.


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